| Agent Name |
Chlorpromazine |
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| CAS Number |
50-53-3 |
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| Formula |
C17-H19-Cl-N2-S |
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| Major Category |
Other Chemicals |
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| Synonyms |
2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine; Chloropromazine; Ormazine; Thor-prom; Thorazine; Largactil; [ChemFinder] |
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| Category |
Pharmaceuticals |
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| Comments |
Allergic and photoallergic contact dermatitis reported in pharmaceutical, healthcare, and animal care workers; [Kanerva, p. 1138] Can cause contact urticaria; [Kanerva 2004, p. 102] As an oral medication, chlorpromazine is used to treat schizophrenia. Many side effects have been reported after ingestion of therapeutic doses, including drug-induced hepatitis. [HSDB] Chlorpromazine may induce photosensitivity in patients taking chlorpromazine systemically (photodrug reaction). [Marks, p. 201-3] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Explanatory Notes |
"Danger of sensitization of skin." [MAK] |
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| Adverse Effects |
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| Dermatotoxin |
Contact Dermatitis, Photoallergic |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CHLORPROMAZINE
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