| Agent Name |
3-Chloroaniline |
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| Alternative Name |
m-Chloroaniline |
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| CAS Number |
108-42-9 |
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| Formula |
C6-H6-Cl-N |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1-Amino-3-chlorobenzene; 3-Chlooranilinen [Dutch]; 3-Chloroaniline; 3-Chlorobenzenamine; 3-Chlorophenylamine; 3-Cloroaniline [Italian]; AI3-12126; Aniline, m-chloro-; Benzenamine, 3-chloro-; Fast Orange GC Base; Orange GC Base; m-Aminochlorobenzene; m-Chloraniline; m-Chloroaminobenzene; m-Chloroaniline; m-Chlorophenylamine; meta-Aminochlorobenzene; [ChemIDplus] UN2019 |
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| Category |
Amines, Aromatic |
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| Description |
Colorless to light amber, tends to darken during storage; [HSDB] |
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| Sources/Uses |
Used as an intermediate to produce herbicides, pharmaceuticals, azo dyes, and pigments; [HSDB] |
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| Comments |
"In the United Kingdom between 1961 and 1980, chloroaniline, p-toluidine, nitrobenzene, and nitrochlorobenzene were the most common industrial causes of methemoglobinemia. Dermal exposure was a more frequent route of toxicity than inhalation with these compounds." (Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988.) A skin and eye irritant; Can induce methemoglobinemia; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.05 mm Hg |
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| Lethal Concentration |
LC50 (mice) = 550 mg/m3/4h |
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| Explanatory Notes |
Flash point = 255 deg F; |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Primary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 3-CHLOROANILINE
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