| Agent Name |
4,6-Dinitro-o-sec-butyl phenol |
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| Alternative Name |
Dinoseb |
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| CAS Number |
88-85-7 |
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| Formula |
C10-H12-N2-O5 |
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| Major Category |
Pesticides |
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| Synonyms |
DNOSBP; F-ISO; Caldon; Vertac General and Selective Weed Killer; Basanite; Chemox General & PE; Chemsect; Dinitrax; Dinitro-3; Dinitro General; Drexel Dynamite 3; Dynamite; Elgetol 318; Hel-Fire; Kiloseb; Nitropone C; Subitex; Unicrop DNBP; Vertac Dinitro Weed Killer 5; Dynanap; Premerge Plus,with Dinitro; Klean Krop; 2-sec-Butyl-4,6-dinitrophenol; DNBP; WSX-8365; Chemox PE; Dow General; Premerge; Dinitrobutyl phenol; Dinoseb Phenol; Dinitro; DNPB; Vertac General Weed Killer; 2,4-Dinitro-6-sec-butylphenol; Butaphene; BNP 30; 4,6-Dinitro-2-(1-methyl-n-propyl)phenol; Nitropone; Phenotan; Sparic; Spurge; Unicorp DNBP; Vertac Dinitro Weed Killer; DNSBP; Dow General Weed Killer; Dow Selective Weed Killer; Dinitro-o-sec-butylphenol; Sinoxgeneral; Dinoseb; 4,6-Dinitro-2-sec-butylphenol; [ChemFinder] |
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| Category |
Herbicides, Nitroaromatic |
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| Sources/Uses |
Consumption patterns in 1986: 40% for soybeans; 16% for peanuts; 15% for potatoes; also used for alfalfa, snap beans, peas, grapes, and almonds; [HSDB] |
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| Comments |
The pathophysiology, like that of pentachlorophenol, involves the uncoupling of oxidative phosphorylation. Yellow stains appear on the skin after dermal contact with the nitroaromatic herbicides. Fatal poisoning can occur after dermal absorption. Cataracts have been reported in animal experiments and after occupational exposure. In severe poisoning, these herbicides can cause injury to the liver and kidneys. [EPA Pesticides, p. 104-5] |
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| Restricted |
All uses cancelled in the U.S. in 1986; [EXTOXNET] |
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| Reference Link |
EXTOXNET - Dinoseb |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Reference Link |
ATSDR - ToxFAQs - Dinitrophenols |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| Other Poison |
Uncoupler |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DINOSEB
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