Protocol Number: 99-C-0025

Title:

The Use of Radiofrequency Ablation to Treat Hepatic Neoplasms

Number:

99-C-0025

Summary:

The Radiofrequency Interstitial Tissue Ablation (RITA) unit and the Radionics CC-1 Cosman Coagulator system, and LeVeen electrodes and RF 2000 generator of the RadioTherapeutics RF Ablation System are FDA approved devices for the treatment of soft tissue. They use a modification of the standard surgical electrocautery that uses heat to destroy tissue. They have incorporated several improvements including multi-tipped cautery needles for the treatment of a larger volume of tissue as well as thermistors built into the tips which allow for accurate control of tissue temperature. There is already a large experience with these devices for the treatment of hepatic neoplasms. This protocol is designed to allow us to gain experience using these devices as well as to evaluate the use of various imaging modalities to determine tissue responses.

Sponsoring Institute:

National Cancer Institute (NCI)

Recruitment Detail

Type: No longer recruiting/follow-up only

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): Children

Eligibility Criteria: This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Special Instructions:

Currently Not Provided

Keyword(s):

Thermal

Cautery

Liver

Heat

Tumor

Recruitment Keyword(s):

None

Condition(s):

Liver Neoplasm

Investigational Drug(s):

Fluorine-18-flourodeoxyglucose (FDG)

Investigational Device(s):

None

Interventions:

Procedure/Surgery: Radiofrequency ablation

Drug: Fluorine-18-flourodeoxyglucose (FDG)

Supporting Site:

National Cancer Institute

Contact(s):

This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Citation(s):

Laparoscopic thermal ablation of hepatic neuroendocrine tumor metastases

Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis

Laparoscopic ablation of a liver adenoma by radiofrequency electrocautery

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department Clinical Research Informatics, CC.

Search The Studies | Help | Questions |
Clinical Center Home | NIH Home

National Institutes of Health Clinical Center
Bethesda, Maryland 20892. Last update: 01/13/2009