Protocol Number: 85-M-0115

Title:

Biological Markers in Childhood Psychiatric Disorders

Number:

85-M-0115

Summary:

The purpose of this study is to evaluate individuals with Attention Deficit/Hyperactivity Disorder (ADHD) to learn more about the genetics of the disease.

This study is part of other ongoing studies of individuals with ADHD. The study participants have already undergone neurobiological measurements, particularly magnetic resonance imaging (MRI) of the brain, through other research studies. As a follow-up to these studies, participants will next undergo psychiatric interviews, neuropsychological tests, and another MRI. In addition to the clinical evaluation of the participants, further research will be conducted on the genetics of ADHD. These genetic studies will evaluate people with ADHD as well as their family members and a control group of healthy people.

Sponsoring Institute:

National Institute of Mental Health (NIMH)

Recruitment Detail

Type: Completed Study; data analyses ongoing

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria: This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Special Instructions:

This is not a treatment protocol.

Keyword(s):

Attention Deficit Hyperactivity Disorder

Disruptive Behavior Disorders

Cerebrospinal Fluid

Lumbar Puncture

CSF

Longitudinal Prospective Follow-Up

Psychosocial Functioning

Risk Factors

Genetics

Recruitment Keyword(s):

None

Condition(s):

Attention Deficit and Disruptive Behavior Disorder

Attention Deficit Disorder with Hyperactivity

Investigational Drug(s):

None

Investigational Device(s):

None

Interventions:

None

Supporting Site:

National Institute of Mental Health

Contact(s):

This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Citation(s):

Affected-sib-pair interval mapping and exclusion for complex genetic traits: sampling considerations

Childhood hyperactivity scores are highly heritable and show sibling competition effects: twin study evidence

Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department Clinical Research Informatics, CC.

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