Protocol Number: 08-N-0198
Men and women between 18 and 75 years of age who served in combat in the Iraq war may be eligible for this study. It will compare test results in those who sustained a traumatic penetrating or blast-related brain injury during combat with those who did not. Participants undergo the following procedures over a 5-day period of testing that lasts about 6 hours a day: -Medical history and physical examination. -Blood test for genetic analysis. -Electroencephalography (EEG) to measure the electrical activity of the brain. -MRI or CT scans of the brain to look at the structure and blood flow of the brain. -Functional near-infrared spectroscopy (fNIRS) to monitor blood flow in the front part of the brain blood by measuring changes in near-infrared light. -Neuropsychological testing, including questionnaires, pen-and-paper or computerized tests, and performance of simple actions to measure brain function, language, memory and other cognitive abilities..
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National Institutes of Health Clinical Center
Bethesda, Maryland 20892. Last update: 01/13/2009
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