Protocol Number: 00-AR-0222
Children and adults of all ages with known or suspected arthritis are eligible for this study. Participants will undergo the following tests and procedures: -Medical history and physical examination - Measurements of weight and height - Blood sample collections for clinical and research purposes - X-rays of hand, feet or other affected joints, if x-rays have not been taken in the past 3 months and are medically indicated - Magnetic resonance imaging (in some patients) to assess disease or study the usefulness of this diagnostic method for arthritis patients - Quality of life questionnaires - Stride analyzer test (children only) - computer system analysis of walking speed and pattern - Hand functional test (children only) - detailed study of hand function - Walk/run time (children only) - measurement of distance the child can walk or run in 9 minutes (heart rate and blood pressure are taken before and after the test) -Synovial biopsy (in some patients) - removal of a sample of tissue from the synovium (lining of the joint) for evaluation under the microscope. The procedure is done under local anesthetic.
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National Institutes of Health Clinical Center
Bethesda, Maryland 20892. Last update: 01/13/2009
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