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Adefovir dipivoxil
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Brand Name: Hepsera  Audio
Drug Class: Opportunistic Infection and Other Drugs

Adefovir dipivoxil, also known as Hepsera, belongs to the class of medicines called antivirals. Antivirals kill viruses or stop viruses from multiplying. Adefovir is a nucleotide analogue that blocks hepatitis B virus (HBV) DNA polymerase, a protein that HBV needs to make more copies of itself.


HIV/AIDS-Related Uses


Adefovir is approved by the FDA for the treatment of chronic HBV infection, a common coinfection in patients with HIV/AIDS.


Dosage Form/Administration


Adefovir comes in tablet form and is taken by mouth.


Contraindications


Individuals should tell a doctor about any medical problems before taking this medicine.


Possible Side Effects


Along with its desired effects, adefovir may cause some unwanted effects. Although not all of these side effects are known, headache, abdominal pain, nausea, diarrhea, bloating, indigestion, and flatulence have been reported. More serious symptoms include loss of muscle control, unusual tiredness, trouble breathing, dizziness, yellowing of the eyes or skin, dark urine, and lack of appetite. Individuals should tell a doctor if they have any of these side effects.

Drug Interactions

A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.


Clinical Trials


Click here to search ClinicalTrials.gov for trials that use Adefovir dipivoxil.


Manufacturer Information


Hepsera
  Gilead Sciences Inc
  333 Lakeside Dr
  Foster City,  CA  94404
  (800) 445-3235
    

Adefovir dipivoxil
  Gilead Sciences Inc
  333 Lakeside Dr
  Foster City,  CA  94404
  (800) 445-3235
    



Updated January 9, 2008