Bipolar Disorder (Adult) Research Study
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Antidepressant (Rapid) Effects of Ketamine
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If you (or someone you know) have been diagnosed with bipolar disorder, you may be able to participate in a trial designed to understand the causes of depression and rapid antidepressant response. Specifically, we are testing whether ketamine, a drug that affects glutamate in the brain will improve symptoms of depression within a matter of hours.
If you are 18-60 years of age and have been diagnosed with bipolar disorder and previously failed to respond to treatment, you may be eligible for an inpatient trial designed to bring about a rapid antidepressant effect.
After completion of the study the participant is transitioned back to a clinician in the community. In addition, all research participation is without cost and we will cover all transportation costs from anywhere in the United States. Compensation is provided for study procedures.
To find out if you qualify or for more information, please call 1-877-MIND-NIH (1-877-646-3644) or email us at moodresearch@mail.nih.gov .
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Bipolar Disorder (Adult) Research Study
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Antidepressant Effects of Ceftriaxone in Bipolar Depression
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If you (or someone you know) have been diagnosed with bipolar disorder (manic depression), you may be able to participate in a trial designed to understand the causes of depression and antidepressant response. Specifically, we are testing whether the antibiotic ceftriaxone, would improve symptoms of depression.
If you are 18-65 years of age and have been diagnosed with bipolar disorder and are currently depressed, you may be eligible for an inpatient trial.
After completion of the study, the participant is transitioned back to a clinician in the community. In addition, all research participation is without cost and we will cover all transportation costs from anywhere in the United States. Compensation is provided for study procedures.
To find out if you qualify or for more information, please call 1-877-MIND-NIH (1-877-646-3644) or email us at moodresearch@mail.nih.gov.
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Bipolar Disorder (Adult) Research Study
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Bipolar Disorder Genetics: A Collaborative Study
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If you have been diagnosed with bipolar disorder (BP) you may be eligible to participate in a research study at the NIH clinical Center. The purpose of this study is to identify genes that may contribute to the development of bipolar disorder (manic depression), and related conditions. Bipolar disorder is a common and potentially life-threatening mood disorder. The tendency to develop bipolar disorder can be inherited, but this is poorly understood and probably involves multiple genes. This study will use genetic markers to map and identify genes that contribute to bipolar disorder.
Families and individuals who have the disorder are asked to contribute personal information and a blood sample to an anonymous national database. This information will aid scientists around the world who are working together to develop better treatments for this serious mood disorder.
To find out if you qualify or for more information, please call 1-866-644-4363 or email us at kazubad@mail.nih.gov.
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Bipolar Disorder (Adult) Research Study
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Brain Imaging in Bipolar Disorder
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If you are currently depressed, you may be eligible to participate in a brain imaging study. This study is being conducted to try to better understand depression in bipolar disorder also know as manic-depressive illness. These are outpatient studies requiring three to four visits. Subjects should be 18 - 60 years of age, currently depressed or never have experienced depression in the past and are otherwise medically healthy and not taking any medication. These studies include medical and psychiatric evaluations, and brain imaging. Compensation is provided.
To find out if you qualify or for more information, please call (301) 594-3186 or email us at drevetsm@mail.nih.gov.
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Bipolar Disorder (Adult) Research Study
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NIMH FAMILY STUDY OF HEALTH AND BEHAVIOR
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The major goal of this study is to examine how mood disorders, anxiety disorders and migraine run in families. We study both genetic and environmental factors that may contribute to these conditions. We recruit people ages 21 and over with depression, manic-depression, social phobia, panic, generalized anxiety, migraine and people without any of these problems. Participants are interviewed about medical and mental symptoms and problems, their health behavior, social factors and a variety of other measures related to their health and behavior. Family members ages 8 and over will also be asked to participate. Some families will be invited to participate in further studies of biological and genetic factors.
To find out if you qualify or for more information, please call 1-877-250-1560 or email at familystudy@mail.nih.gov.
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Bipolar Disorder (Adult) Research Study
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Riluzole to treat Depression in Bipolar Disorder
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If you (or someone you know) have been diagnosed with bipolar depression or manic-depressive illness, you may be able to participate in our clinical trial designed to decrease symptoms of depression and understand the causes of depression. Specifically, we are testing whether riluzole (FDA approved for ALS also known as Lou Gehrig's disease) a drug that affects glutamate in the brain will improve symptoms of depression. We are also conducting neuropsychological testing in this study.
If you are 18-70 years of age and have been diagnosed with bipolar depression, you may be eligible for an outpatient or inpatient clinical trial of riluzole in bipolar depression.
After completion of the study the participant is transitioned back to a clinician in the community. In addition, all research participation is without cost and we will cover all transportation costs from anywhere in the United States. Compensation is provided for participation in neuropsychological exams.
To find out if you qualify or for more information, please call 1-877-MIND-NIH (1-877-646-3644) or email us at moodresearch@mail.nih.gov.
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