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Research Studies        
Pioglitazone Asthma Clinical Trial   Lymphangioleiomyomatosis (LAM) Treatment Research Study   Pulmonary Hypertension - Research Screening Study  
Genetics of Asthma Research Study   Familial Pulmonary Fibrosis Research Evaluation Study   walk-PHaSST Pulmonary Hypertension Trial  
Cystic Fibrosis Research Study   Pulmonary Fibrosis Research Evaluation Study   Pulmonary Sarcoidosis Treatment Trial
Lymphangioleiomyomatosis (LAM) and Tuberous Sclerosis Research Study   Inhaled Nitric Oxide and Sildenafil Study  

Asthma Research Study

Pioglitazone Asthma Clinical Trial

Patients with asthma who are taking inhaled corticosteroids may be eligible to participate in a study at the NIH Clinical Center. The purpose of this study is to determine if a widely used medication for diabetes can improve asthma. Eligible patients will receive a comprehensive evaluation at the Clinical Research Center in Bethesda, Maryland. There is no cost for participating in the study.
For further information, please contact our research coordinator, toll-free, at 1-877-NIH-LUNG (1-877-644-5864), extension 2 or via email at LungStudy@nhlbi.nih.gov. You may also contact the NIH Patient Recruitment and Public Liaison Office via TTY 1-866-411-1010.
 
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Asthma Research Study

Genetics of Asthma Research Study

If you have been diagnosed with asthma and allergies, you may be able to participate in an asthma genetics research study at the NIH Clinical Center. The purpose of this research is to identify genes that may be involved in the development or severity of asthma.

Eligible volunteers will undergo a comprehensive medical and pulmonary evaluation at the NIH Clinical Center in Bethesda, MD. There is no cost to you for medical testing and evaluation. You will receive monetary compensation for participating in the study.

For further information, please contact our research coordinator toll free at 1-877-NIH-LUNG (1-877-644-5864), extension 2; email: LungStudy@nhlbi.nih.gov
 
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Cystic Fibrosis Research Study

Cystic Fibrosis Research Study

If you have been diagnosed with cystic fibrosis (CF), you may be eligible to participate in a research study at the NIH Clinical Center. The purpose of this research is to improve understanding of CF. Those with CF 9 years of age and older will undergo a pulmonary evaluation at the NIH Clinical Center in Bethesda, MD.

There is no cost to you for travel or medical testing, and should you wish, information from your evaluation will be provided for your physicians.

For further information, please contact our research coordinator at the toll free telephone:1-800-411-1222; e-mail: LungStudy@nhlbi.nih.gov.
 
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Lymphangioleiomyomatosis (LAM) Research Study

Lymphangioleiomyomatosis (LAM) and Tuberous Sclerosis Research Study

If you have been diagnosed with Lymphangioleiomyomatosis (or LAM) or with tuberous sclerosis complex (TSC), you may be eligible to participate in a research study at the NIH Clinical Center. The purpose of this research study is to improve our understanding of LAM and TSC. Eligible patients undergo a comprehensive pulmonary evaluation at the Clinical Center in Bethesda, MD.

There is no cost to you for travel or medical testing and, should you wish, information from your evaluation will be provided for your physicians.

For further information, please contact our research coordinator at toll free telephone: 1-877-NIH-LUNG (1-877-644-5864), extension 3, email: LungStudy@nhlbi.nih.gov.
 
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Lymphangioleiomyomatosis (LAM) Research Study

Lymphangioleiomyomatosis (LAM) Treatment Research Study

If you have been diagnosed with lymphangioleiomyomatosis and have developed fluid in the lungs (chylous effusions), you may be eligible to participate in our research study. If eligible, you will undergo a comprehensive pulmonary and medical evaluation at the Clinical Center in Bethesda, MD. The purpose of this study is to test the effectiveness of a medication called octreotide on symptoms and chylous effusions. Octreotide is a medicine, that in other studies was helpful in reducing chylous ascites, effusions and other disorders associated with lymphatic flow.

There is no cost to you for travel or medical testing, and should you wish, information from your evaluation will be provided for your physicians.

For further information, please contact our research coordinator at toll free telephone: 1-877-NIH-LUNG (1-877-644-5864),
extension 3, or e-mail:LungStudy@nhlbi.nih.gov
 
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Pulmonary Fibrosis Research Study

Familial Pulmonary Fibrosis Research Evaluation Study

If you or two of your relatives have been diagnosed with familial pulmonary fibrosis, you and your relatives may be eligible to participate in a research study at NIH Clinical Center. The purpose of this research is to improve the understanding of the natural history of this disease and its underlying cause(s). Eligible volunteers undergo a comprehensive medical and pulmonary evaluation at NIH Clinical Center in Bethesda, MD.

There is no cost for to you for travel or medical testing, and should you wish, information from your evaluation will be provided for your physicians.

For further information, please contact our research coordinator at toll free telephone: 1-877-NIH-LUNG (1-877-644-5864), extension 1; e-mail: LungStudy@nhlbi.nih.gov.
 
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Pulmonary Fibrosis Research Study

Pulmonary Fibrosis Research Evaluation Study

If you have been diagnosed with pulmonary fibrosis (or IPF), you may be eligible to participate in a research study at NIH Clinical Center. The purpose of this research is to improve the understanding of the natural history of pulmonary fibrosis and its underlying cause(s). Eligible volunteers undergo a comprehensive medical and pulmonary evaluation at the NIH Clinical Center in Bethesda, MD.

There is no cost to you for travel or medical testing, and should you wish, information from your evaluation will be provided for your physicians.

For further information, please contact our research coordinator at toll free telephone: 1-877-NIH-LUNG (1-877-644-5864), extension 1; e-mail: LungStudy@nhlbi.nih.gov.
 
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Pulmonary Hypertension Research Study

Inhaled Nitric Oxide and Sildenafil Study

Individuals who have sickle cell disease and pulmonary hypertension (increased blood pressure in the lungs) sometimes have more complications (shortness of breath, pain crises, pneumonia, and death). Because of this increased risk, this clinical trial will evaluate if experimental treatments for high blood pressure in the lungs can lower pressures in the lungs and reduce the likelihood of complications. The study has three parts.

The first part involves a thorough screening of your heart and lungs. These tests will be performed on an outpatient or inpatient basis. The second part is specialized testing at the Clinical Center, during which blood pressure in the blood vessels going to your lungs (pulmonary artery) will be measured. The third part of the study is for experimental treament, during which the drug sildenafil will be combined with inhaled nitric oxide gas for 6 weeks. This can be done as either an inpatient or outpatient and you must have been taking sildenafil for 3 months and still have high blood pressure in the lungs.

For more information, please contact study coordinators, Lori Hunter or Wynona Coles at 301-435-2345 or email VascularStudy@nhlbi.nih.gov
 
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Pulmonary Hypertension Research Study

Pulmonary Hypertension - Research Screening Study

Researchers at the NIH invite you to take part in a study that will help us learn how often people with sickle cell anemia develop a complication called pulmonary hypertension. Pulmonary hypertension is a serious disease in which blood pressure in the artery to the lungs is elevated.

You are eligible to participate if you are 18 years of age or older and have sickle cell disease. This study consists of an initial evaluation (including a physical exam, blood tests, and an echocardiogram), a follow-up telephone interview every year after the initial echocardiogram, and a repeat echocardiogram and blood tests approximately two years after the first. There is no cost to participate.

Please contact the study coordinator at 301-402-2104 for more information or email VascularStudy@nhlbi.nih.gov
 
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Pulmonary Hypertension Research Study

walk-PHaSST Pulmonary Hypertension Trial

This clinical research study will test the ability of the drug, sildenafil, to decrease elevated blood pressure in the pulmonary artery (the blood vessel that leads from the heart to the lungs).

You may be eligible to participate in this study if you are over the age of 12 and have sickle cell disease and symptoms or lung tests indicating that the blood pressure in your pulmonary (lungs) artery may be elevated. This condition is called pulmonary hypertension. Pulmonary hypertension can cause fatigue, dizziness, and shortness of breath because the blood vessels that supply the lungs narrow, forcing the heart to work harder to push blood through.
For more information please contact Wynona Coles at 301-435-2345 or email LungStudy@nhlbi.nih.gov
 
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Sarcoidosis Research Study

Pulmonary Sarcoidosis Treatment Trial

If you have been diagnosed with sarcoidosis of the lung, you may be eligible to participate in a study at the NIH Clinical Center. The purpose of this study is to determine if a widely used cholesterol-lowering agent can decrease the amount of prednisone (steroids) required to manage your illness. Eligible patients will receive a comprehensive evaluation at the Clinical Center in Bethesda, Maryland.

There is no cost to you for travel or medical testing.

For further information, please contact our research coordinator, toll free, at 1-877-NIH-LUNG (1-877-644-5864), e-mail: LungStudy@nhlbi.nih.gov, or you may call Sandra MacDonald, RN at 301-451-4899. Alternatively, you may reach the NIH Patient Recruitment and Public Liaison Office via TTY 1-866-411-1010.

 
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