Medicine: Mind the Gap
.
Bridging the Gap Between Evidence and Practice
An NIH Seminar Series

Inaugural Event

Monday, November 5, 2007  
Webcast and Slides Now Available

Natcher Conference Center, E1/E2
9:30 – 11:00 a.m.
Refreshments to follow



The Medicine: Mind the Gap series will explore a wide range of issues at the intersection of research, evidence, and clinical practice—especially  areas in which conventional wisdom may lead us astray. 

From the role of advocacy organizations in medical research and policy, to off-label drug use, to the effectiveness of continuing medical education, the seminar series will aim to engage the NIH community in thought-provoking discussions to challenge what we think we know and to think critically about our role in today’s research environment. 

We anticipate holding three to four seminars per year and welcome your suggestions for topics and speakers. 

Contact Us:
NIH Office of Medical Applications of Research
Kelli Marciel
marcielk@od.nih.gov
301.496.4819 

Presented by the NIH Consensus Development Program
Celebrating 30 Years of Service


Inaugural Event

Chaos in the brickyard:
Translational research in 2007

Guest Speaker
David F. Ransohoff, M.D.
Professor, Departments of Medicine and Epidemiology
University of North Carolina at Chapel Hill

Monday, November 5, 2007

Natcher Conference Center, E1/E2
9:30 – 11:00 a.m.
Refreshments to follow

“Chaos in the brickyard” refers to a letter[1] that appeared in Science in 1963, in which Bernard K. Forscher described scientific research as the building of brick edifices:

“Once upon a time, among the activities and occupations of man there was an activity called scientific research and the performers of this activity were called scientists.  In reality however, these men were builders who constructed edifices, called explanations or laws, by assembling bricks, called facts…If the bricks were faulty or if they were assembled badly, the edifice would crumble…”  

When investigators from basic and clinical fields collaborate to do translational research, special problems arise in determining whether research results are 'strong'. Examples of current problems will be discussed, along with 'rules of evidence' and broader principles that may help improve translational research.

Sign Language Interpreters will be provided. Individuals with disabilities who need reasonable accommodation to participate in this event should contact the Office of Medical Applications of Research at marcielk@od.nih.gov | 301.496.4819

Live and archived videocast will be available at videocast.nih.gov.



[1] Forscher, BK. Chaos in the Brickyard.  Science. 1963 Oct 18; 142(3590): 339.