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 General Information: Measles
Surveillance
Genotyping Results United States
Genotyping Results: International
Measles Lab Manual (English)
Measles Lab Manual (Español)
Vero/SLAM cell line
Serology
Specimens for Measles Virus Isolation
 Publications
Genetic Analysis
Guidelines for Naming
Strains or Sequences
Measles Strain Banks
 Genetic Characterization
and Sequencing

en español

Guidelines for Naming Measles Strains or Sequences

The strain names will provide information that is essential for interpretation of the molecular data. Since sequence data may be derived from viruses isolated in cell culture or from RNA extracted directly from clinical material, strains or sequences will be designated as either

(1)
MVi: measles virus isolate in cell culture; or
(2)
MVs: measles virus sequence derived from RNA extracted
from clinical material.

Other information to be included in the strain/sequence name:

-
city/province where case of measles was diagnosed, write full name or abbreviation
(required);
-
country, use WHO 3-letter (exit site) designation (required);
-
date of specimen collection by epidemic week (1-52)
and year (required);
-
isolate number if more than 1 per week in the same location (optional);
-
genotype (optional initially, required after sequencing
of at least 450 nucleotides of the N gene (text-only) is completed);
-
special designation for sequences derived from measles
inclusion body encephalitis (MIBE) or subacute
sclerosing panencephalitis (SSPE) cases (optional).

The following examples illustrate the proposed nomenclature:

MVi/NewYork.USA/03.98/2 [D2]

MVs/London.UNK/17.97 [G3] SSPE

 

Update of the nomenclature for describing the genetic characteristics of wild-type measles viruses: new genotypes and reference strains. ( Wkly Epi Rec July 4 2003; 78:229-232).adobe acrobat (exit site)

Nomenclature for describing the genetic characteristics of wild-type measles viruses (update). (WHO/Wkly. Epi Rec Aug 10 2001;76:242-257).adobe acrobat (exit site)

Other sources of information for Measles surveillance
item Pan American Health Organization
EuroSurveillance

Central Public Health Laboratory, UK

item Canada: Laboratory Centre for Disease Control
item Chile: Surveillance
item World Health Organization
Measles Initiative
Note: The links in this box lead outside the CDC site. Any links from these sites to nonfederal organizations links do not constitute an endorsement of these organizations or their programs by CDC or the federal government, and none should be inferred. CDC is not responsible for the content of the individual organization Web pages found at these links.

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This page last reviewed January 4, 2006


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