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Sickle Cell Disease
Sickle Cell Disease home > Facts Trait
Facts About Sickle Cell Trait


Questions and AnswersPeople who inherit one sickle cell gene and one normal gene have the sickle cell “trait”. People with sickle cell trait usually do not have any of the symptoms of the disease, but they can pass it on to their children.

To learn more about sickle cell trait click on one of the following links or scroll down the page.

 


Q How is sickle cell trait diagnosed?

A Sickle cell trait is diagnosed with a simple blood test. People at risk of having sickle cell trait can talk to a doctor or health clinic about getting this test.

Did you know:
People at high risk for having sickle cell trait are those whose ancestors come from Africa, South or Central America, Caribbean, Mediterranean countries, India, and Saudi Arabia.

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Q Are there any complications?

A It is possible for a person with sickle cell trait to experience complications of sickle cell disease, such as splenic sequestration, “pain crisis”, and, rarely, sudden death.

This can happen under extreme conditions of:

  • High altitude (flying, mountain climbing, or cities with a high altitude)
  • Increased pressure (scuba diving)
  • Low oxygen (mountain climbing or exercising extremely hard, such as in military boot camp or when training for an athletic competition)
  • Dehydration (too little water in the body)

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Q Can women with sickle cell trait have a healthy pregnancy?

photo of woman who is pregnantA Yes; women who have sickle cell trait can have a healthy pregnancy. People who inherit one sickle cell gene and one normal gene have the sickle cell “trait”. People with sickle cell trait usually do not have any of the symptoms of the disease and live a normal life, but they can pass the disease on to their children.

A genetic counselor can provide information about the chance of passing the disease to the baby.

During pregnancy, there is a test to find out if the baby will have sickle cell disease, sickle cell trait, or neither one. The test is usually conducted after the second month of pregnancy.

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Q What is the chance of a person with sickle cell trait having a child with sickle cell trait or sickle cell disease?

DNA strandA Sickle cell disease is “recessive”, which means that both parents must pass on the sickle cell gene for a child to be born with the disease. A genetic counselor can provide information about the chance of passing the disease to the baby.

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Thank you for visiting the CDC-NCBDDD Web site. Click here to contact the National Center on Birth Defects and Developmental Disabilities

We are not able to answer personal medical questions. Please see your health care provider concerning appropriate care, treatment, or other medical advice.
 

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National Center on Birth Defects and Developmental Disabilities

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