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Slide 38
Hantavirus Infection Sequelae
Hantavirus Spectrum of Illness: Hantavirus infections can
be asymptomatic, cause a mild hantaviral illness or HPS (hantavirus
pulmonary syndrome).
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Slide 39
HPS National Surveillance
HPS Case Definition
HPS National Surveillance -- HPS Case Definition: HPS is a febrile
illness with a temperature of 38.3ºC or greater, characterized
by bilateral interstitial pulmonary infiltrates, respiratory compromise
usually requiring supplemental oxygen, and clinically resembling
acute respiratory distress syndrome. An autopsy may reveal noncardiogenic
pulmonary edema with no identifiable specific cause of death. |
Slide 40
HPS National Surveillance
Mild Hantaviral Illness Case Definition
HPS National Surveillance -- Mild Hantaviral Illness: This
case definition includes febrile illness of a temperature
of 38.0ºC or greater without bilateral diffuse interstitial
or alveolar infiltrates. |
Slide 41
HPS National Surveillance
Comments
HPS National Surveillance -- Comments: The full clinical spectrum
of HPS is undefined. HPS cases can have a mild pulmonary disease
or involve a renal component. Depending on resources, more
sensitive screening criteria could include mild pulmonary
disease, unexplained acute febrile renal disease, and other
febrile syndromes. |
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Slide 42
Shipping
Shipping Guidelines for Diagnostic Specimens – Safety:
Label specimens as “infectious substance”. Use a
double layered container with absorbent material between layers
sufficient to absorb the volume being sent. Use plastic tubes
rather than glass. Shipping conditions: Serum samples should
be shipped at room temperature or on cold packs. Clot or buffy
coat specimens should be shipped on dry ice. Fresh tissue
should be in 1cm cubes and on dry ice. Formalin-fixed tissues
and paraffin blocks should be at room temperature and not
frozen.
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Slide 43
Submitting Specimens
Submitting Specimens: For details on specimen types and volumes
for submission, HPS case reports, and national surveillance
laboratory specimen forms, call 404-639-1511, or visit www.cdc.gov/ncidod/diseases/hanta/hps/index.htm
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National
Center for Infectious Diseases
