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Public Release: 15-Jan-2009
Proceedings of the National Academy of Sciences
Scripps research team develops new technique to tap full potential of antibody libraries
Antibodies are the attack dogs of the immune system, fighting off bacterial and other invaders. Massive libraries of synthetic antibodies that mimic this natural response, for instance to attack proteins critical to a particular cancer, are also available, but current techniques have allowed scientists to screen these antibodies for effectiveness against only a very limited number of disease-causing agents.
Scripps Research Institute, Skaggs Institute for Chemical Biology, Pfizer, Inc.
Contact: Keith McKeown
kmckeown@scripps.edu
858-784-8134
Scripps Research Institute
Public Release: 15-Jan-2009
Science
E. coli persists against antibiotics through HipA-induced dormancy
Bacteria hunker down and survive antibiotic attack when a protein flips a chemical switch that throws them into a dormant state until treatment abates, researchers at the University of Texas M. D. Anderson Cancer Center report in the Jan. 16 edition of Science.
Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Public Release: 15-Jan-2009
Health provisions among public's top priorities for economic stimulus
The public ranks action on health care highly as part of efforts to stem the impact of the economic recession and also views reforming health care as one of the top priorities for President-elect Obama and Congress, according to a new national survey.
Contact: Todd Datz
tdatz@hsph.harvard.edu
617-432-3952
Harvard School of Public Health
Public Release: 15-Jan-2009
International Journal of Geriatric Psychiatry
Does universal health care affect attitude toward dementia?
In spite of their universal health care system which facilitates access to free dementia care, older adults in the United Kingdom are less willing to undergo dementia screening than their counterparts in the US because the Britons perceive greater societal stigma from diagnosis of the disease than do Americans according to researches from Indiana University and the Universities of Kent and London.
NIH/National Institute on Aging
Contact: Cindy Fox Aisen
caisen@iupui.edu
317-274-7722
Indiana University
Public Release: 15-Jan-2009
Addiction
Alcohol taxes have clear effect on drinking
A new study published online today finds that the more alcoholic beverages cost, the less likely people are to drink.
Contact: Molly Jarvis
molly@addictionjournal.org
44-020-784-80014
Wiley-Blackwell
Public Release: 15-Jan-2009
Cancer Epidemiology, Biomarkers & Prevention
Reduced breast cancer risk: Physical activity after menopause pays off
The breast cancer risk of women who are regularly physically active in the postmenopausal phase is reduced by about one third compared to relatively inactive women. This is the result of a study of the German Cancer Research Center and the University Hospitals of Hamburg-Eppendorf.
Contact: Dr. Sibylle Kohlstädt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Public Release: 15-Jan-2009
Journal of Bone and Mineral Research
Researchers detail how aging undermines bone healing
Researchers have unraveled crucial details of how aging causes broken bones to heal slowly, or not at all, according to study results published today in the Journal of Bone and Mineral Research. The research team also successfully conducted preclinical tests on a potential new class of treatments designed to "rescue" healing capability lost to aging.
National Institutes of Health
Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
585-267-7557
University of Rochester Medical Center
Public Release: 15-Jan-2009
Current Biology
DREAM: 1 gene regulates pain, learning and memory
The DREAM-gene which is crucial in regulating pain perception seems to also influence learning and memory. This is the result of studies carried out by researchers in Seville, Spain, and Vienna, Austria. The new findings could help explain the mechanisms of Alzheimer's disease and yield a potential new therapeutic target.
Junta de Andalucia, Direccion General de Investigacion Ciencia y Tecnica, FPU fellowship program, Spanish Ministry of Education and Science, Austrian Academy of Sciences, Austrian Ministry of Science
Contact: Dr. Heidemarie Hurtl
hurtl@imp.ac.at
43-179-730-3625
Research Institute of Molecular Pathology
Public Release: 15-Jan-2009
Lancet
Countries undergoing economic change urged to limit social and health costs for populations
Countries seeking to make massive changes in the way their economies are run, for example by privatizing formerly state-run sectors, must take into account the potential impact of such changes on people's health, experts warn today.
Contact: Gemma Howe
gemma.howe@lshtm.ac.uk
020-792-72802
London School of Hygiene & Tropical Medicine
Public Release: 15-Jan-2009
International Journal of Health Geographics
Global warming linked to European viral epidemic
An epidemic of the viral disease nephropathia epidemica has been linked to increases in the vole population caused by hotter summers, milder winters and increased seedcrop production by broadleaf trees. Research published in BioMed Central's open access International Journal of Health Geographics links outbreaks of this rodent-borne disease to known effects of global warming.
Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-020-707-94804
BioMed Central
Public Release: 15-Jan-2009
British Medical Journal
Postnatal depression can be effectively treated and possibly prevented
Health visitors can be trained to identify women with postnatal depression and offer effective treatment, while telephone peer support (mother to mother) may halve the risk of developing postnatal depression, suggests research published on bmj.com today.
Contact: Emma Dickinson
edickinson@bmj.com
44-020-738-36529
BMJ-British Medical Journal
Public Release: 15-Jan-2009
American Journal of Ophthalmology
Paintballs can cause 'devastating' eye injuries
Paintballs can cause severe and 'visually devastating' eye injuries, especially when used in unsupervised settings without proper eye protection, reports a study in the February issue of the American Journal of Ophthalmology, published by Elsevier.
Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3671
Elsevier
Public Release: 15-Jan-2009
American Journal of Epidemiology
Moderate alcohol consumption may help seniors keep disabilities at bay
It is well known that moderate drinking can have positive health benefits. For instance, a couple of glasses of red wine a day can be good for the heart. But if you're a senior in good health, light to moderate consumption of alcohol may also help prevent the development of physical disability.
John A. Hartford Foundation, American Federation for Aging Research Medical Student Geriatrics Scholars Program, NIH/National Institute on Alcohol Abuse and Alcoholism, et al
Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles
Public Release: 15-Jan-2009
Clinical Cancer Research
Abnormal DNA repair genes may predict pancreatic cancer risk
Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreatic cancer, a research team from the University of Texas M. D. Anderson Cancer Center reports in the Jan. 15 issue of Clinical Cancer Research.
Contact: Laura Sussman
lsussman@mdanderson.org
713-745-2457
University of Texas M. D. Anderson Cancer Center
Public Release: 15-Jan-2009
BMC Public Health
The key to a healthy lifestyle is in the mind
The main factors influencing the amount of physical exercise people carry out are their self-perceived ability and the extent of their desire to exercise. A study of 5167 Canadians, reported in the open access journal BMC Public Health, has shown that psychological concerns are the most important barriers to an active lifestyle.
Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-020-707-94804
BioMed Central
Public Release: 15-Jan-2009
PLoS Pathogens
Researchers find essential proteins for critical stage of malaria
Researchers have identified the molecular components that enable the malaria-causing parasite Plasmodium to infect the salivary glands of the Anopheles mosquito -- a critical stage for spreading malaria to humans. The findings are published Jan. 16 in the open-access journal PLoS Pathogens.
Contact: Tim Parsons
tmparson@jhsph.edu
410-955-7619
Public Library of Science
Public Release: 15-Jan-2009
CA: A Cancer Journal for Clinicians
News from CA: A Cancer Journal for Clinicians
Highlights from this issue include an overview on the progress made in studies of pharmacogenetics and pharmacogenomics; a report on adherence to drug therapy among patients with cancer and interventions to improve compliance rates; the American Cancer Society's annual summary of its recommendations for early cancer detection, including data and trends in cancer screening rates and select issues related to cancer screening; and a report on the important aspects of lymphedema, including the anatomy, pathophysiology, diagnosis and management of this condition.
Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Public Release: 15-Jan-2009
Science
New genetic model predicts plant flowering in different environments
A Brown University-led team has created a model that precisely charts the genetic and environmental signals that guide the life cycle of a scientifically important plant species. The model could help scientists better understand how plants will respond to climate change. The paper is published in the online edition of Science.
National Science Foundation, Alexander von Humboldt Foundation
Contact: Richard Lewis
Richard_Lewis@Brown.edu
401-863-3766
Brown University
Public Release: 15-Jan-2009
Science
Easy assembly of electronic biological chips
A handheld, ultra-portable device that can recognize and immediately report on a wide variety of environmental or medical compounds may eventually be possible, using a method that incorporates a mixture of biologically tagged nanowires onto integrated circuit chips, according to Penn State researchers.
National Institutes of Health, National Science Foundation
Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Public Release: 15-Jan-2009
Clinical Cancer Research
DNA repair patterns may predict risk of pancreatic cancer
Genetic variations in DNA repair patterns may increase risk of pancreatic cancer by as much as threefold or decrease it by as much as 77 percent, depending on the genes involved, according to a report published in the Jan. 15, 2009, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Public Release: 15-Jan-2009
Molecular Cell
Mutant host cell protein sequesters critical HIV-1 element
Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis. The research, published by Cell Press in the Jan. 16 issue of the journal Molecular Cell, presents a target for development of antiretroviral therapeutics that are likely to complement existing therapies and provide additional protection from HIV and AIDS.
Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Public Release: 15-Jan-2009
PLoS Genetics
Study of human tissue reveals potential colon cancer biomarker
University of Cincinnati scientists have identified a new biomarker that could help predict a person's risk of developing colon cancer and how aggressive it may become.
National Institutes of Health, US Army
Contact: Amanda J. Harper
amanda.harper@uc.edu
513-558-4657
University of Cincinnati
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