Primary Navigation for the CDC Website
CDC en EspaƱol

Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition

NOTE: - Printed booklets, HTML and Spanish versions not yet available

U.S. Department of Health and Human Services
Centers for Disease Control and Prevention
National Institutes of Health
Fifth Edition, Feb 2007

US Government Printing Office
Washington: 2007

Complete 5th Edition of BMBL (All Sections) PDF
(PDF - 2.4 MB)

Table of Contents

Title Page and Credits Biosafety in Microbiological and Biomedical Laboratories, 5th Edition
SECTION I Introduction
SECTION II Biological Risk Assessment
SECTION III Principles of Biosafety
SECTION IV Laboratory Biosafety Level Criteria
Table 1 (Sect.IV) Summary of Recommended Biosafety Levels for Infectious Agents
SECTION V Vertebrate Animal Biosafety Level Criteria, for Vivarium Research Facilities
Table 1 (Sect.V) Summary of Recommended Biosafety Levels for Activities in Which Experimentally or Naturally Infected Vertebrate Animals Are Used.
SECTION VI Principles of Laboratory Biosecurity
SECTION VII Occupational Health and Immunoprophylaxis
SECTION VIII Agent Summary Statements
SECTION VIII-A Bacterial Agents
SECTION VIII-B Fungal Agents
SECTION VIII-C Parasitic Agents
SECTION VIII-D Rickettsial Agents
SECTION VIII-F Arboviruses and Related Zoonotic Viruses
Table 3 Alphabetic Listing of 597 Arboviruses and Hemorrhagic Fever Viruses
SECTION VIII-H Prion Diseases
APPENDIX A Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets
APPENDIX B Decontamination and Disinfection
APPENDIX C Transportation of Infectious Substances
APPENDIX D Agriculture Pathogen Biosafety
APPENDIX E Arthropod Containment Guidelines
APPENDIX F Select Agents and Toxins
APPENDIX G Integrated Pest Management
APPENDIX H Working with Human, NHP and Other Mammalian Cells and Tissues
APPENDIX I Guidelines for Work with Toxins of Biological Origin
APPENDIX J NIH Oversight of Research Involving Recombinant Biosafety Issues
APPENDIX K Resources for Information

* Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. CDC is not responsible for the content of the individual organization Web pages found at these links.

PDF Document Icon Please note: Some of these publications are available for download only as *.pdf files. These files require Adobe Acrobat Reader in order to be viewed. Please review the information on downloading and using Acrobat Reader software.

Page last modified: March 31, 2008
Page last Reviewed: March 31, 2008