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The Nation's Investment in Cancer Research FY 2009

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Related Pages
Breast Cancer Home Page
NCI's gateway for information about breast cancer.

Breast Cancer Trial Results
Provides links to clinical trial results about breast cancer.
Treatment
Breast Cancer Treatment (PDQ®)
[ patient ] [ health professional ]
Expert-reviewed information summary about the treatment of breast cancer.

Male Breast Cancer Treatment (PDQ®)
[ patient ] [ health professional ]
Expert-reviewed information summary about the treatment of male breast cancer.

Breast Cancer Treatment and Pregnancy (PDQ®)
[ patient ] [ health professional ]
Expert-reviewed information summary about the treatment of breast cancer during pregnancy.

Clinical Trials to Treat Breast Cancer
Check for breast cancer treatment trials from NCI's PDQ® Cancer Clinical Trials Registry now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.

New Study of Targeted Therapies for Breast Cancer Establishes Model for Global Clinical Trials
Two targeted medications designed to treat an aggressive form of breast cancer are being tested in a new study, called ALTTO, involving 8,000 participants in 50 countries across six continents -a clinical trial that investigators hope will provide a new model for global cancer research.

Brain Scans Show Structural Effects of Chemotherapy
The cognitive impairments demonstrated by breast cancer patients who undergo chemotherapy - symptoms commonly called "chemobrain" - may be related to structural brain changes, according to an article published early online November 27, 2006, in the journal Cancer.

New Trastuzumab Regimen Lessens Cardiac Side Effects
A Finnish study on therapies for early breast cancer reports lower cardiac side effects among women who received a shorter than standard course of treatment with trastuzumab (Herceptin®), according to the Feb. 23, 2006, issue of the New England Journal of Medicine.

Herceptin® Combined With Chemotherapy Improves Disease-Free Survival for Patients With Early-Stage Breast Cancer
Results from two large randomized clinical trials for patients with HER-2 positive invasive breast cancer show that those patients with early-stage breast cancer who received Herceptin® (trastuzumab) in combination with chemotherapy had a significant decrease in risk for breast cancer recurrence compared with patients who received the same chemotherapy without trastuzumab.

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer
Preliminary results from a large, randomized clinical trial for patients with previously untreated recurrent or metastatic breast cancer show that those patients who received bevacizumab (Avastin™) in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same chemotherapy without bevacizumab. Questions and Answers

Age Associated with Type of Breast Cancer Treatment
Women 75 or older with early-stage breast cancer are more likely to receive nonstandard primary tumor therapy in an integrated health care setting, according to the Sept. 20, 2006, Journal of Clinical Oncology.

Radiation Therapy for Breast Cancer Now Less Risky for Heart
The risk of death from heart disease caused by radiation therapy for breast cancer has declined steadily over the past 25 years, according to a study published in the March 16, 2005 issue of the Journal of the National Cancer Institute.

Molecular Test Can Predict Both the Risk of Breast Cancer Recurrence and Who Will Benefit From Chemotherapy
A new test can predict both the risk of breast cancer recurrence and may identify women who will benefit most from chemotherapy.

Dose-Dense Chemotherapy Helped Patients with Metastatic Breast Cancer
Weekly administration of the drug Taxol® (paclitaxel) to patients with breast cancer that had spread to other parts of the body resulted in a higher response rate and a longer delay until patients' disease progressed, compared with conventional administration of the drug every three weeks.

Surgery Choices for Women with Early-Stage Breast Cancer
A booklet for women who have early-stage breast cancer (DCIS or Stage I, IIA, IIB, or IIIA). The booklet describes breast cancer surgery choices including breast-sparing surgery, mastectomy, and breast reconstruction surgery.

Adjuvant Therapy for Breast Cancer
Information and recommendations about treating breast cancer from an NIH Consensus Development Conference held in November 2000.

Adjuvant Therapy for Breast Cancer: Questions and Answers
A fact sheet that explains types of adjuvant therapies (treatment given in addition to primary therapy). Discusses side effects, risks, and benefits of adjuvant therapy. National Cancer Institute Fact Sheet 7.20

Tamoxifen: Questions and Answers
A fact sheet that describes the action, risks, benefits, and side effects of tamoxifen, a drug that interrupts the hormone estrogen and its connection to breast cancer. National Cancer Institute Fact Sheet 7.16

Aromatase Inhibitors
A collection of information about aromatase inhibitors, a hormone therapy used in the treatment of some women with breast cancer.

Early Breast Cancer Patients Benefit from Shortened Chemotherapy
Women with one type of early breast cancer get the same benefit from three months of one chemotherapy as they do from six months of another drug combination.

High-Dose Chemotherapy for Breast Cancer
A collection of material about high-dose chemotherapy with bone marrow or stem cell transplant as a treatment for breast cancer.

Hormone Therapy Increases Survival for Some Breast Cancer Patients
A drug commonly used for prostate cancer, buserelin, helped premenopausal women with advanced breast cancer live longer, according to a report in the June 7, 2000, issue of the Journal of the National Cancer Institute.

Inflammatory Breast Cancer: Questions and Answers
A fact sheet about the diagnosis and treatment of inflammatory breast cancer, an uncommon type of cancer in which the breast becomes red, swollen, and warm. National Cancer Institute Fact Sheet 6.2

Sentinel Lymph Node Biopsy: Questions and Answers
A fact sheet that describes the sentinel lymph node biopsy procedure and details two clinical trials evaluating the effectiveness of this procedure. National Cancer Institute Fact Sheet 7.44

Paget Disease of the Nipple: Questions and Answers
A fact sheet about Paget disease of the nipple, an uncommon type of breast cancer that is sometimes called mammary Paget's disease. National Cancer Institute Fact Sheet 6.39

Angiogenesis Inhibitors Therapy
A fact sheet that describes the process of eliminating the blood supply to tumors. Lists the cancers in which this approach is being tested. National Cancer Institute Fact Sheet 7.42

Biological Therapies for Cancer: Questions and Answers
A fact sheet that provides an overview of how the immune system functions and describes the actions of biological therapies. National Cancer Institute Fact Sheet 7.2

Biological Therapy
An introduction to biological therapy to help patients prepare to receive it for cancer treatment or managing side effects.

Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation
A fact sheet that explains the step-by-step procedures of two types of transplantations used with high-dose chemotherapy, including their risks and benefits. National Cancer Institute Fact Sheet 7.41

Radiation Therapy for Cancer: Questions and Answers
A fact sheet that defines the different types of radiation therapy and discusses scientific advances that improve the effectiveness of this treatment. National Cancer Institute Fact Sheet 7.1

Targeted Cancer Therapies: Questions and Answers
This NCI fact sheet describes targeted cancer therapies, which are drugs that block the growth and spread of cancer by interfering with specific molecules involved in carcinogenesis (the process by which normal cells are transformed into cancer cells) and tumor growth. National Cancer Institute Fact Sheet 7.49

Metastatic Cancer: Questions and Answers
A fact sheet about metastasis, the spread of cancer to other parts of the body. Discusses the diagnosis and treatment of cancer that has spread. National Cancer Institute Fact Sheet 6.20

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