Fonts are an implementation issue. They have nothing to do with record
interchange, which is what MARC 21 is about.
The problematic characters are the "half marks" (U+FE20 through U+FE23) The
"half marks" are primarily used in romanizing languages written in Cyrillic
script. Using the original script will solve the problem for transcribed
text (as Frances McNamara pointed out), though not Latin script access points.
Arial Unicode MS doesn't iinclude glyphs for the "half mark" characters, but
some fonts, for example, Code 2000 do. So maybe those who are concerned
about display issues need to investigate use of a font other than Arial
Unicode MS. This is purely related to *your* system, so should be taken up
on a users' group list (or perhaps on the AVIAC list or the MARC IG as Jim
Agenbroad suggested).
-- Joan Aliprand