Resolution No. 6/08-5

ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES
VACCINES FOR CHILDREN PROGRAM
VACCINES TO PREVENT Haemophilus influenza type b 
The purpose of this resolution is to incorporate the use of a pentavalent vaccine: diphtheria 
and tetanus toxoids, acellular pertussis, haemophilus influenza type b, and polio vaccines and to clarify 
the recommended schedule for the currently available vaccines for prevention of 
Haemophilus influenza type b.

VFC resolution 2/99-3 is repealed and replaced by the following:  
Eligible groups 
All children 6 weeks to 5 years of age. 
Recommended Schedule for Haemophilus influenza type b (Hib) Vaccines
The recommended schedule included 3 or 4 doses of a Hib containing vaccine by age 2 years, depending 
on the specific vaccine.  The Hib doses should be given at the following ages:
Dose					Age
Primary 1 				2 months
Primary 2 				4 months
Primary 3 				6 months*
Booster 				12-15 months

*The third dose of the primary series is not necessary if PRP-OMP Hib vaccines (PedvaxHib® or Comvax®) 
are administered at age 2 and 4 months.  If any dose in the primary series utilizes PRP-T Hib vaccines (ACTHib® or Pentacel®), 
the third primary dose at age 6 months is required.  TriHIBit® (DTaP/Hib) should not be used for the primary series, but can be 
used for the booster doses in children age 12 months or older.
NOTE: Use of brand names is not meant to preclude the use of other licensed Hib vaccines.



Minimum age and intervals for Hib vaccines
Minimum age: 6 weeks
Mininum Intervals for Primary Series Doses: Up to Age 12 Months/4weeks
Mininum Interval for Booster Dose: Age 12 Months or older/8 weeks

Catch-Up Vaccination 
The ACIP recommends Haemophilus influenzae type b vaccine for all children through 5 years of age. 
If Hib vaccination is not initiated by 6 months of age, use the following schedule and consult
the ACIP approved Catch-up Schedule:

(Table)
Age at first vaccination: 7-11 months
Primary series: 2 doses at least 4 weeks apart
Booster: Age 12-15 months at least 8 weeks after the second dose

Age at first vaccination: 12-14 months
Primary series: 1 dose
Booster: 1 dose at least 8 weeks after the first dose

Age at first vaccination: 15-59 months
Primary series: 1 dose
Booster: N/A
(End Table)

Recommended dosage  
Refer to product package inserts. 


Precautions and contraindications 
The following conditions are contraindications to the administration of Haemophilus influenzae type b vaccine: 
1 Allergy to vaccine components Anaphylactic reaction to the vaccine or a constituent of the vaccine. 
2 Acute, moderate or severe illnesses with or without fever 
Adopted and Effective: June 26, 2008

















This document can be found on the CDC website at:
http://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/0608hib.txt