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Abstract
Grant Number: 7R01AT001103-05 Project Title: The Safety and Efficacy of Low and High Carbohydrate Die
PI Information: Name Title FOSTER, GARY D. gary.foster@temple.edu PROFESSOR Abstract: Despite the considerable mass appeal of popular diet books, such approaches lack data to support their efficacy and safety. Despite its widespread use for more than 30 years, the Atkins diet has never been evaluated in a large randomized controlled trial (RCT). Data from large RCTs are necessary to help physicians, patients and the broader health care community make informed decisions about the safety and efficacy of these programs. The current proposal will assess the short-term and long-term clinical effects of the Atkins diet in 360 obese men and women. Participants will be randomized to the Atkins diet (low-carbohydrate, unlimited fat and protein) or a conventional USDA diet (high-carbohydrate, low-fat). The effects of each dietary approach on changes in: 1) weight and body composition; 2) metabolic and organ function; and 3) exercise tolerance will be evaluated.
Public Health Relevance:
This Public Health Relevance is not available.Thesaurus Terms:
diet therapy, human therapy evaluation, obesity, reducing diet
acidosis, aerobic exercise, blood lipid, blood pressure, body composition, bone density, cholesterol, dietary carbohydrate, dietary lipid, dietary protein, dietary restriction, functional ability, hunger, insulin sensitivity /resistance, longitudinal human study, metabolism, physical fitness, physiology, vascular endothelium, weight loss
adult human (21+), human subject, nutrition related tag, patient oriented research
Institution: TEMPLE UNIVERSITY 1601 N. BROAD STREET PHILADELPHIA, PA 19122 Fiscal Year: 2006 Department: MEDICINE Project Start: 15-MAY-2002 Project End: 28-FEB-2008 ICD: NATIONAL CENTER FOR COMPLEMENTARY & ALTERNATIVE MEDICINE IRG: NTN