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Infant Deaths Associated with Cough and Cold Medications

During 2004--2005, an estimated 1,519 children aged less than 2 years were treated in U.S. emergency departments for adverse events, including overdoses, associated with cough and cold medications. In response to reports of infant deaths after such events, CDC and the National Association of Medical Examiners (NAME) investigated deaths in U.S. infants aged less than 12 months associated with cough and cold medications. This report describes the results of that investigation, which identified three infants aged less than 6 months whose deaths were attributed to cough and cold medications.   During 2004--2005, an estimated 1,519 children aged less than 2 years were treated in U.S. emergency departments for adverse events, including overdoses, associated with cough and cold medications. In response to reports of infant deaths after such events, CDC and the National Association of Medical Examiners (NAME) investigated deaths in U.S. infants aged less than 12 months associated with cough and cold medications. This report describes the results of that investigation, which identified three infants aged less than 6 months whose deaths were attributed to cough and cold medications.

Date Released: 3/9/2007
Running time: 4:59
Author: MMWR
Series Name: A Cup of Health with CDC

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A CUP OF HEALTH WITH CDC
Infant Deaths Associated with Cough and Cold Medications – Two States, 2005
March 9, 2007

[Announcer] This podcast is presented by the Centers for Disease Control and
Prevention. CDC – safer, healthier people.

[Matthew Reynolds] Welcome to A Cup of Health with CDC, a weekly broadcast of the
MMWR, the Morbidity and Mortality Weekly Report. I’m your host, Matthew Reynolds.
Winter is cold season and that probably means you have a supply of cough and cold
medicines on hand. But it’s important to check with your doctor before reaching for
these medicines for your child under two. Cold medicines contain a number of
ingredients including decongestants, antihistamines, and cough suppressants. These
ingredients can be dangerous and even deadly when they reach very high levels in the
blood. In the two years CDC studied, over fifteen hundred children under the age of two
were treated in emergency rooms for side effects or overdoses of cough and cold
medications.

Here to discuss what you can safely do when your child has a cold is Dr. Adam Cohen
of CDC’s Division of Healthcare Quality Promotion. Dr. Cohen is part of a team that
recently investigated infant deaths due to cold and cough medicine. Welcome to the
program, Dr. Cohen.

[Dr. Cohen] Thank you, Matthew.

[Matthew Reynolds] Dr. Cohen, do cough and cold medicines work in children under
two years old?

[Dr. Cohen] Although these medicines may be helpful in adults and older children, there
really is little evidence that cough and cold medicines work in children under the age of
two. And in addition, there are no approved dosing recommendations from the Food
and Drug Administration for children under two. We should keep in mind that these
drugs can, in rare cases, be harmful or even fatal.

[Matthew Reynolds] What did you and your co-workers find in your study?

[Dr. Cohen] We found that deaths in infants from cough and cold medicines do occur,
although they are extremely rare. In our nationwide survey, we identified only three
infants who died from the toxic effects of cough and cold medicines in 2005.

[Matthew Reynolds] What precautions should our listeners take if they think their infant
requires medicine for a cold?

[Dr. Cohen] Parents should never give children under the age of two any over-thecounter
or prescription cold medicines without first talking to their doctor or clinic.
And they should be especially careful before giving more than one cough or cold
medicine at the same time to their baby or toddler. Parents should talk to their doctor
first to find out what medicines and doses are safe for children under two. Cold
medicines have different brand names but may contain the same or similar ingredients.
And some cough and cold medicines contain more than one active ingredient. Giving
more than one cough or cold medicine at the same time could be dangerous for children
under two and could possibly result in an overdose.

[Matthew Reynolds] Surely the parents that are listening to this would like to have
options for their child. And if giving them medicines isn’t an option, what can they do
instead of giving those cough and cold medications to their infant?

[Dr. Cohen] There are some simple things that parents can do. We certainly want to
help children that are suffering from a cough or cold. Parents can use a cool-mist
humidifier in the baby’s room to help with the congestion and stuffy nose that comes
with a cold. Parents might also try clearing nasal congestion in infants by gently using a
rubber suction bulb. A stuffy nose may also be helped by using saline nose drops. And
all of these are available without prescription.

[Matthew Reynolds] Let’s say the parents have given their children medication. What
should they do if they are worried about an overdose?

[Dr. Cohen] If parents are ever worried about a poisoning emergency, they should call
the poison control center. And if someone’s child has collapsed or is not breathing, they
should call 911.

[Matthew Reynolds] Dr. Cohen, thanks for taking the time to talk with us today.

[Dr. Cohen] Thank you, Matthew. It was great to be here.

[Matthew Reynolds] That’s it for this week’s show. Don’t forget to join us next week.
Until then, be well. This is Matthew Reynolds for A Cup of Health with CDC.

[Announcer] To access the most accurate and relevant health information that affects
you, your family, and your community, please visit www.cdc.gov.

  Page last modified Friday, March 09, 2007

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