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Clinical Trials in Bethesda, MD
Clinical trials are medical research studies designed to answer specific questions about new therapies, procedures, or treatments, by testing them in people. This carefully conducted research helps to determine if the therapy is safe and effective.
Intramural Clinical Trials Seeking Patients
The following NCCAM clinical trials are taking place in Bethesda, Maryland.
Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuro-Endocrine Function in Men
Chronic pain and its treatment with opioid-related medicines, are increasing in our society, yet little is known about their underlying biology. To further understand these phenomena, this study will evaluate the effects of chronic musculoskeletal pain and treatment with morphine and placebo medications on stress and sex hormones in middle-aged men with symptomatic osteoarthritis. Hormone function will also be assessed in healthy, age-matched men, not treated with morphine or placebo medication. More information >>> (ClinicalTrials.gov)Contact information for this study:
Joni Poe, R.N., B.S.N., M.A.
Phone: 301-594-9512
E-mail: poej@mail.nih.govor
Patient Recruitment and Public Liaison Office
Phone: 1-800-411-1222
E-mail: prpl@mail.cc.nih.govSee more clinical trials around the country related to osteoarthritis. (ClinicalTrials.gov)
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Effects of Dark Chocolate Consumption on Insulin Sensitivity and Capillary Recruitment in Subjects with Essential Hypertension
Dark chocolate and other cocoa products contain antioxidants including epicatechin that have beneficial effects on vascular function. Past studies showed that eating dark chocolate lowered blood pressure in elderly subjects and drinking cocoa improved flow-mediated vasodilatation. Research has also shown that regulation of hemodynamic and metabolic homeostasis are coupled such that individuals with essential hypertension are also insulin resistant. This study will examine whether dark chocolate consumption will improve both blood pressure and insulin sensitivity in people with essential hypertension. More information >>> (ClinicalTrials.gov)The dark chocolate study has completed enrollment.
Effect of EGCG on the Body's Response to Insulin
Drinking green tea is associated with decreased cardiovascular mortality in epidemiological studies. In laboratory studies, we found that the green tea catechin epigallocatechin-3-gallate (EGCG) is a bioactive polyphenol that mimics or augments beneficial metabolic, vascular, and anti-inflammatory actions of insulin in cells and in animals. Type 2 diabetes, obesity, and hypertension are diseases characterized by the presence of insulin resistance and endothelial dysfunction. Therapies that improve insulin resistance often simultaneously improve endothelial function and vice versa.This clinical study will examine whetheroral EGCG therapy improves insulin resistance or lowers blood pressure in healthy individuals and in people with diabetes, obesity, or high blood pressure. Results from this study may have important implications for understanding potential health benefits of functional foods that contain bioactive polyphenols including green tea, dark chocolate, and red wine. More information >>> (ClinicalTrials.gov)
Contact information for this study:
Gloria Shuler, RN, BSN
Phone: (301) 496-3244
E-mail: shulerg@mail.nih.gov
Effect of Tai Chi Chuan Compared to a Structured Exercise Program on Parameters of Physical Fitness and Stress in Adult Cancer Survivors
This study will compare the effectiveness of tai chi (a sequence of slow, graceful body movements) and a cardiovascular exercise fitness program in improving physical fitness and endurance, reducing stress and improving well-being in adult survivors of cancer. Participants are randomly assigned to one of three study groups: tai chi, exercise training, or a waiting list. Individuals in the tai chi and exercise training groups participate in a supervised program for 1 hour 3 times a week for 12 weeks in the NIH Clinical Center.
More information >>>
Download our flier (PDF) >>>Contact information for this study:
Patient Recruitment and Public Liaison Office
Phone: 1-800-411-1222
E-mail: prpl@mail.cc.nih.gov- Mistletoe Extract and Gemcitabine for the Treatment of Solid Tumor Cancers
This study will examine the safety and effectiveness of the combination of mistletoe extract and gemcitabine in patients with solid tumor cancers. Gemcitabine is approved by the Food and Drug Administration to treat various cancers, including those of the lung, bowel, breast and pancreas. FDA has approved mistletoe extract for use in cancer treatment studies. Mistletoe extract has been used either alone or together with conventional anti-cancer drugs to treat cancer in tens of thousands of patients in Europe. Data from some studies suggest that this substance may stimulate the immune system and may make cancer patients feel better overall. More Information >>>
Contact information for this study:
Patient Recruitment and Public Liaison Office
Phone: 1-800-411-1222
E-mail: prpl@mail.cc.nih.gov - A Randomized Study of Electroacupuncture Treatment for Delayed Chemotherapy-induced Nausea and Vomiting in Patients with Pediatric Sarcomas
This clinical trial is studying the effectiveness of electroacupuncture in treating delayed nausea and vomiting in patients who are receiving chemotherapy for newly diagnosed childhood sarcoma, neuroblastoma, nasopharyngeal cancer, or germ cell tumors. More Information >>> (ClinicalTrials.gov)
Contact information for this study:
Patient Recruitment and Public Liaison Office
Phone: 1-800-411-1222
E-mail: prpl@mail.cc.nih.gov
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