Version 2.5.2.0 CRISP Logo CRISP Homepage Help for CRISP Email Us

Abstract

Grant Number: 1K23AT002298-01A1
Project Title: Mind-Body Therapies to Prevent Chronic Low Back Pain
PI Information:NameEmailTitle
MEHLING, WOLF E. mehlingw@ocim.ucsf.edu

Abstract: DESCRIPTION (provided by applicant): While about 10% of patients presenting with acute low back pain (aLBP) will develop chronic low back pain (cLBP), they consume about 75% of LBP related health care expenses and constitute a major economic burden for society. The transition from acute to cLBP is associated with multiple risk factors, of which psychosocial risk factors have the greatest predictive power. This suggests an interaction between emotion, coping, and cognition (mind) and the physical experience of LBP (body). CAM modalities emphasizing the mind-body link, such as Mindfulness Based Stress Reduction, Feldenkrais, and Yoga, may modify these risk factors and help prevent cLBP. Clinicians currently do not have a simple, validated tool for identifying patients with aLBP at high risk for chronic pain and it is unclear whether (and, if so, which) CAM therapies can modify the risk profile and outcome in patients presenting with aLBP. Such information would aid in planning controlled trials of mind-body therapies for LBP, in identifying possible mechanisms of action of these therapies, and in targeting health care resources for cLBP prevention. The candidate will conduct 2 projects: (1) a prospective cohort study (n = 620) at Kaiser Permanente, Northern California (a) to develop and validate a brief prediction tool for primary care clinics and (b) to assess changes in risk factors over time and their association with changes in LBP outcomes; (2) an assessment of whether specific mind-body therapies alter the variables measured with the new prediction tool in randomized and observational studies. The candidate will pursue a structured educational program that includes coursework, mentoring, and supervision of these projects to develop the necessary skills in behavioral science, psychometric evaluation of measures, and clinical research implementation. The candidate's overall goal is to become an independent investigator conducting clinical research of mind-body approaches for the prevention of cLBP.

Public Health Relevance:
This Public Health Relevance is not available.

Thesaurus Terms:
alternative medicine, backache, chronic pain, disease /disorder proneness /risk, human therapy evaluation, medical outreach /case finding, meditation, pain, patient oriented research, prognosis, stress management
avoidance behavior, chronic disease /disorder, cognition, coping, emotional adjustment, fear, pathologic process, psychometrics, psychosomatic disorder, social psychology
behavioral /social science research tag, clinical research, human data, human subject

Institution: UNIVERSITY OF CALIFORNIA SAN FRANCISCO
3333 California St., Ste 315
SAN FRANCISCO, CA 941430962
Fiscal Year: 2005
Department: MEDICINE
Project Start: 01-APR-2005
Project End: 30-JUN-2010
ICD: NATIONAL CENTER FOR COMPLEMENTARY & ALTERNATIVE MEDICINE
IRG: ZAT1


CRISP Homepage Help for CRISP Email Us