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Clinical Case Study 4

A company plans to send a large number of employees to work in Afghanistan, for variable periods of time. Their employees’ health service inquires about potential need for malaria prevention.

Question 1: Will there be a malaria risk in Afghanistan? And if yes, where and when?

Question 2: For a 34-year-old male employee, with no known medical problems, which of the following drugs would constitute appropriate chemoprophylaxis? (More than one answer might be correct.)

Question 3: Which one of these drugs would be appropriate for a 30-year-old woman, at her 20th week of pregnancy, traveling to Afghanistan?

Question 4: Which of these drugs would be appropriate for a 64-year-old man traveling to Afghanistan, who has a history of cardiac conduction abnormalities, but no other medical problems? (More than one answer might be correct.)

Main points:

  • Recommendations about chemoprophylaxis should take into account:
    • transmission patterns (areas of risk, time of year)
    • Plasmodium species being transmitted
    • patterns of drug resistance
    • travelers' personal and medical characteristics
    • duration and intensity of exposure

 

Page last modified : April 23, 2004
Content source: Division of Parasitic Diseases
National Center for Zoonotic, Vector-Borne, and Enteric Diseases (ZVED)

 

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