NASA SBIR 2004 Solicitation

FORM B - PROPOSAL SUMMARY


PROPOSAL NUMBER: 04 B2.03-8663
SUBTOPIC TITLE: Understanding and Utilizing Gravitational Effects on Molecular Biology and for Medical Applications
PROPOSAL TITLE: Single Electron Transistor Platform for Microgravity Proteomics

SMALL BUSINESS CONCERN (Firm Name, Mail Address, City/State/Zip, Phone)
QUANTUM LOGIC DEVICES
7801 North Lamar, Suite B-161
Austin ,TX 78752 - 1017
(512) 302 - 5030

PRINCIPAL INVESTIGATOR/PROJECT MANAGER (Name, E-mail, Mail Address, City/State/Zip, Phone)
Louis   Brousseau
lou@quantumlogicdevices.com
7801 North Lamar, Suite B-161
Austin, TX  78752 -1017
(512) 302 - 5030

TECHNICAL ABSTRACT (LIMIT 200 WORDS)
Proteomic studies in microgravity are crucial to understanding the health effects of spaceflight on astronauts. Unfortunately, existing tools for measuring protein, antibody, and enzyme expression are limited to earth-borne laboratories due to their complexity and size. This proposal offers a novel technology that provides a palm-top platform suitable for real-time experiments on the Space Shuttle or International Space Station. The technology uses nanoelectronic transistors coupled to antibody bioprobes to provide a label-free "direct detection" system that is rapid and easy to use with minimal skill. The system is completely self-contained, including all reagents and waste products, and operated from a PDA-style handheld computer. Phase I will demonstrate the detection concept and Phase II will deliver prototype units for testing.

POTENTIAL NASA COMMERCIAL APPLICATIONS (LIMIT 100 WORDS)
The proposed endpoint of this program is a handheld bioassay system that would be ideally suited for all biomedical research and diagnostic needs of current and future space missions.

POTENTIAL NON-NASA COMMERCIAL APPLICATIONS (LIMIT 100 WORDS)
Point of care and telemedical diagnostics are the most rapidly growing segment of the medical testing market, for which this technology would be ideally suited.


Form Printed on 09-20-04 20:19