Peptide Derivatives Of Cytochrome b558 And Their Use As Medicaments [As Anti-Inflammatory Agents]
Description of Invention:
A new anti-inflammatory agent based on two c-terminal amino acid sequences of cytochrome b558 has been shown to inhibit the production of toxic oxygen products (superoxide, peroxide) by human phagocytic cells. Because of its specificity for phagocytic cells, it is expected that these peptide derivatives would not have the side effects of other anti-inflammatory agents in general use.
Inventors:
H Malech (NIAID) D Rotrosen (NIAID)
Patent Status:
DHHS Reference No. E-263-1988/1 --
U.S. Patent No. 5,593,966 issued 14 Jan 1997
For Additional Information Please Contact: Fatima Sayyid M.H.P.M.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-4521
Email: sayyidf@mail.nih.gov
Fax: (301) 402-0220
