Identification Of A Region Of The Major Surface Glycoprotein (MSG) Gene Of Human Pneumocystis carinii
Description of Invention:
Pneumocystis carinii is an important life-threatening opportunistic pathogen of
immuno-compromised patients, especially for those with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). The present invention provides for methods and kits for detecting Pneumocystis carinii infection
in humans. More specifically, nucleic acid amplification (for example, polymerase chain reaction (PCR) amplification) of human Pneumocystis carinii MSG-encoding genes (approximately 100 copies of which are present per genome), may provide a particularly sensitive and specific technique for the detection of Pneumocystis carinii and the diagnosis of Pneumocystis carinii pneumonia (PNP).
Inventors:
Joseph Kovacs et al. (CC)
Patent Status:
DHHS Reference No. E-145-1998/0 --
U.S. Patent 6,664,053 issued 16 Dec 2003 Licensing Status: This technology is no longer available for licensing.
For Additional Information Please Contact: Sally Hu PhD MBA
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5606
Email: hus@mail.nih.gov
Fax: (301) 402-0220
