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Molecular Diagnosis of Disseminated Candida albicans Infection Using Hemoglobin-Response Gene

Description of Invention:
Three hemoglobin-response genes from Candida albicans have been isolated. These genes are induced when the organism initiates systemic infections, coming into contact with hemoglobin. Further, the methods and composition of the included nucleic acid sequences and encoded proteins can be used in the development of reagents and kits used to discriminate between commensal colonization and the more life threatening disseminated infection.

Inventors:
David D. Roberts (NCI)
Sizhuang Yan (CC)

Patent Status:
DHHS Reference No. E-086-1999/0 --
U.S. Patent No. 6,875,855 issued 05 Apr 2005

Portfolios:
Infectious Diseases

Infectious Diseases -Diagnostics-Other
Infectious Diseases -Therapeutics-Other
Infectious Diseases -Diagnostics
Infectious Diseases -Therapeutics


For Additional Information Please Contact:
Robert M. Joynes J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301)594-6565
Email: joynesr@mail.nih.gov
Fax: (301) 402-0220


Web Ref: 356

Updated: 11/03

 

 
 
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