Identification and Use of High Efficacy Vaccine Antigens Which Modulate Antigen Presenting Cells
Description of Invention:
Through modulation of the activation state of an antigen presenting cell (APC), the activation of a T cell is concordantly governed, e.g., the activation of a killer T cell. The subject invention accordingly provides uses and applications in the field of immunology for novel pharmaceuticals, therapeutic and prophylactic agents, and vaccine components for the treatment and prevention of cancer, systemic infection, and autoimmune responses.
Inventors:
Polly Matzinger and John P. Ridge (NIAID)
For Additional Information Please Contact: Peter A. Soukas J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-4646
Email: soukasp@mail.nih.gov
Fax: (301) 402-0220
