Mammalian Guanine Nucleotide-Binding Protein with an ADP-Ribosylation Factor Domain (ARD1)
Description of Invention:
ADP-ribosylation factors (ARFs) constitute one family of the -20-kDa guanine nucleotide-binding ras superfamily. ARFs regulate secretory, endocytic, exocytic, and nuclear fusion events and activate phospholipase D and cholera toxin. ARD1 is a 64-kDa protein containing an ARF domain at its carboxy terminus. This invention includes a cell line transfected with an expression vector containing either rat or human ARD-1 DNA and an immunoassay kit for detecting ARD proteins in samples.
Inventors:
Joel Moss (NHLBI) et al.
Patent Status:
DHHS Reference No. E-037-1993/0 --
U.S. Patent No. 5,386,021 issued 31 Jan 1995
U.S. Patent No. 5,514,600 issued 07 May 1996
Portfolios: Infectious Diseases
Infectious Diseases -Therapeutics
For Additional Information Please Contact: Jasbir (Jesse) S. Kindra J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5559
Email: kindraj@mail.nih.gov
Fax: (301) 402-0220
