Method of Identifying and Using Drugs with Selective Effect Against Cancer Cells
Description of Invention:
The invention covers a method of identifying drugs which selectively inhibit the growth of particular cancer cells. This is accomplished by contacting cancer cells, which differ as to the presence of a particular DNA sequence with a drug and measuring the effect of the drug on growth of the cells. A determination is then made as to whether there is a correlation between the growth rate and presence or absence of the DNA sequence.
The invention may potentially be applied in research and development of cancer therapeutics, or as a diagnostic. It may provide the ability to design combinations of drugs for cancer treatment.
Inventors:
George F. Vande Woude (NCI) Han-Mo Koo (NCI) Anne P. Monks (NCI)
Cancer -Therapeutics-Conventional Chemotherapy-Other Cancer -Therapeutics Cancer -Research Materials
For Additional Information Please Contact: Susan S. Rucker J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-4478
Email: ruckersu@mail.nih.gov
Fax: (301) 402-0220
