Human Monoclonal Antibodies Against Hendra and Nipah Viruses
Description of Invention:
Available for licensing are neutralizing human monoclonal antibodies against the envelope proteins (Envs) of Hendra virus (HeV) and Nipah virus (NiV) for uses in immunotherapy, vaccine development and as diagnostic or research reagents. Monoclonal antibody variable region fragments (Fabs and scFvs) have been isolated from screening a human phage display library against the Envs. The phage display library (DHHS Ref. No. E-188-2007) is useful for screening other viral or cancer antigens and can be licensed from DHHS under a biological materials license.
Patent Status:
DHHS Reference No. E-004-2005/0 --
U.S. Provisional Application No. 60/624,247 filed 01 Nov 2004
PCT Application No. PCT/US2005/040050 filed 04 Nov 2005, which published as WO 2006/137931 on 28 Dec 2006
Licensing Status: In addition to licensing, the technology is available for further development through collaborative research opportunities with the inventors.
For Additional Information Please Contact: Michael Shmilovich J.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-5019
Email: shmilovm@mail.nih.gov
Fax: (301) 402-0220
