Anti-Mesothelin Antibodies Useful for Immunological Assays
Description of Invention:
This invention provides antibodies that have a surprisingly good combination of affinity for mesothelin and ability to be used in immunological assays for detecting the presence of mesothelin in biological samples. The invention further relates to methods of using antibodies and kits comprising them. The antibodies can also be used to target toxins and other agents to cells expressing mesothelin, and can be used in methods and medicaments for inhibiting the growth of such cells.
Inventors:
Ira H. Pastan and Masanori Onda (NCI)
Patent Status:
DHHS Reference No. E-015-2005/0 --
U.S. Provisional Application No. 60/681,104 filed 12 May 2005
PCT Application No. PCT/US2006/018502 filed 11 May 2006 Licensing Status: In addition to licensing, the technology is available for further development through collaborative research opportunities with the inventors.
Portfolios: Cancer
Cancer -Diagnostics
For Additional Information Please Contact: David A. Lambertson Ph.D.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301)435-4632
Email: lambertsond@mail.nih.gov
Fax: (301) 402-0220
