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Metastasis Suppressor Gene on Human Chromosome 8 and Its Use in the Diagnosis, Prognosis and Treatment of Cancer

Description of Invention:
This invention is directed to an isolated or purified ribonucleic acid (RNA) molecule comprising a nucleotide sequence encoded by a human Tey1 metastasis suppressor gene located at p21-p12 on chromosome 8 or a fragment thereof, wherein the isolated or purified RNA molecule comprises from about 10 to about 100 nucleotides. The invention also provides methods of diagnosis, prognosis, and treatment of cancer, such as prostate cancer, using the isolated or purified RNA molecule.

Inventors:
J. Carl Barrett et al. (NCI)

Patent Status:
DHHS Reference No. E-226-2004/0 --
U.S. Provisional Application No. 60/591,028 filed 26 Jul 2004
U.S. Patent Application No. 11/190,027 filed 26 Jul 2005

Portfolios:
Cancer

Cancer -Therapeutics-Gene Therapy-Genes
Cancer -Therapeutics

For Additional Information Please Contact:
Jennifer Wong
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301)435-4633
Email: wongje@mail.nih.gov
Fax: (301)402-0220

Web Ref: 1065

Updated: 4/05