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Water-Soluble, Antineoplastic Derivatives of Taxol

Description of Invention:
A new class of taxol derivatives offer an improved method for treating certain cancers. The use of taxol as an antineoplastic agent has been limited due to poor solubility in aqueous solutions. These new taxol derivatives have improved water solubility while retaining the cytotoxic properties of the parent compounds. Their method of synthesis and use in treating cancer patients are provided.

Inventors:
Rudiger D. Haugwitz et al. (NCI)

Patent Status:
DHHS Reference No. E-090-1987/0-US-01 -- U.S. Patent 4,942,184 issued 17 Jul 1990

Portfolios:
Cancer

Cancer -Therapeutics-Conventional Chemotherapy-Hormonal Compounds
Cancer -Therapeutics-Conventional Chemotherapy-Other
Cancer -Therapeutics


For Additional Information Please Contact:
John Stansberry Ph.D.
NIH Office of Technology Transfer
6011 Executive Boulevard, Suite 325
Rockville, MD 20852-3804
Phone: (301)435-5236
Email: stansbej@mail.nih.gov
Fax: (301) 402-0220


Web Ref: 1056

Updated: 3/05

 

 
 
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