Compositions and Methods for the Treatment of Immune-Related Disease
Description of Invention:
The ability of the immune system to discriminate between self and non-self is controlled by central and peripheral tolerance mechanisms. One of the most important ways the immune system controls the outcome of such a response is through naturally occurring CD4+CD25+ regulatory T cells.
The present invention relates to compositions and methods for treating immune related disease, a method for determining the presence of or predisposition to an immune related disease, and a pharmaceutical composition for treating an immune related disease in a mammal.
Inventors:
F. Xavier Valencia and Peter E. Lipsky (NIAMS)
Patent Status:
DHHS Reference No. E-355-2004/0 --
U.S. Provisional Application No. 60/641,990 filed 02 Nov 2004
PCT Application No. PCT/US2005/039282 filed 05 Oct 2005, which published as WO 2006/074370 on 13 Jul 2006
Licensing Status: In addition to licensing, the technology is available for further development through collaborative research opportunities with the inventors.
Portfolios: Internal Medicine
Internal Medicine-Therapeutics
For Additional Information Please Contact: Fatima Sayyid M.H.P.M.
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: (301) 435-4521
Email: sayyidf@mail.nih.gov
Fax: (301) 402-0220
