Abell, P. (1995). Novel
restraint device for oral dosing of rabbits. Contemporary Topics in
Laboratory Animal Science 34 (6): 86-87, ISSN: 1060-0558.
NAL Call Number: SF405.5.A23
Keywords: oral administration,
restraint of animals, behavior, animal welfare.
Aleman, C.L.; Noa, M.; Mas,
R.; Rodeiro, I.; Mesa, R.; Menendez, R.; Gamez, R.; Hernandez, C. (2000). Reference
data for the principal physiological indicators in three species of laboratory animals.
Laboratory Animals London
34 (4): 379-385.
NAL Call Number: QL55.A1L3
Keywords: laboratory
animal, mouse, strain, NMRI, dog, breed, beagle, rabbit, New Zealand, reference
data, principal physiological indicators, inter laboratory comparisons, species
related reference data, sex differences, hematology, organ weight to body
weight ratio, serum biochemistry.
Barnett, S.W. (2001). Introduction
to Animal Technology Blackwell Science Ltd.: Oxford,
UK; Malden, MA,
112 p., ISBN: 0632055944.
NAL Call Number: SF406.I58
2001
Keywords: laboratory
animal, care and use, scientific research, hamster, cat, dog, ferret, guineapig, marmoset, mouse, rat, rabbit, rhesus monkey, housing, environment,
management, routine procedures, technology, animal welfare, breeding, caging,
euthanasia, experimentation, feeding, handling, health status, hygiene,
identification, laboratory safety, physical development, sexing, watering,
careers, animal technology, legislation, Animals Scientific Procedures Act of
1986.
Bayans, M. (1998). Some
Preferred Techniques for the Laboratory Rabbit. [Quelques Techniques Choisies
Pour Le Lapin De Laboratoire.] Canadian Association of Laboratory
Animals Science: Winnipeg, Canada. VHS video cassette (17
min).
NAL Call Number:
Videocassette no. 2792
Abstract: This is the
second video in our species specific series on laboratory techniques. Safe
handling and restraint for injections, blood sampling and anesthesia with
resuscitation methods are demonstrated. This training video id designed as a teaching
aid to refine, replace and reduce the numbers of rabbits used for demonstration
purposes. The target audience includes animal health technologists, graduate
students, laboratory assistants and members of animal care and use committees.
For more information go to: http://www.calas-acsal.org/.
Keywords: laboratory
techniques, injections, anesthesia with resuscitation, animal welfare.
Boucher, S. (2001). Imagerie
medicale chez les NAC (nouveaux animaux de compagnie): L’echographie chez les
Rongeurs et chez les Lagomorphes. [Imaging in new pets: ultrasonography in
Rodentia and lagomorphs.] Le Point Veterinaire 32 (214): 12-13, ISSN:
0335-4997.
NAL Call Number: SF602.P6
Keywords: pets, echography,
diagnosis, French language.
Brown, S.A. (2001). The domestic
rabbit: husbandry and clinical techniques. Proceedings of the North
American Veterinary Conference 15:
843-844. In the volume: Small Animal and Exotics. Part of
a three volume set. Meeting held January 13-17, 2001 in Orlando, Florida.
NAL Call Number: SF605
N672
Keywords: caging, exercise,
diet, tooth wearing, feed, injuries, handling, veterinary methods, nasogastric
tubing, blood collection, fluid administration, catheterization,
dacryocystitis.
Chatham, J.C.,
Blackband, S.J. (2001). Nuclear magnetic resonance spectroscopy and imaging
in animal research. ILAR Journal 42 (3): 189-208, ISSN: 1084-2020.
NAL Call Number:
QL55.A1I43
Abstract: Nuclear magnetic
resonance (NMR) spectroscopy and imaging can be used to investigate,
noninvasively, a wide range of biological processes in systems as diverse as
protein solutions, single cells, isolated perfused organs, and tissues in vivo.
It is also possible to combine different NMR techniques enabling metabolic,
anatomical, and physiological information to be obtained in the same
experiment. This review provides a simple overview of the basic principles of
NMR and outlines both the advantages and disadvantages of NMR spectroscopy and
imaging. A few examples of potential applications of NMR spectroscopy and
imaging are presented, which demonstrate the range of questions that can be
asked using these techniques. The potential impact of using NMR techniques in a
biomedical research program on the total number of animals required for
specific investigations, as well as the number of animals used in research, are
discussed. The article concludes with a personal perspective on the impact of
continuing improvements in NMR technology for future applications in animal
research.
Keywords: review, mice,
rabbits, rats, anatomy, cross-sectional, animal welfare, laboratory animals,
physiology, aplysia, cytology, magnetic resonance imaging, magnetic resonance
spectroscopy, research methods, tumor cells.
Ewringmann, A.; Göbel, T.
(1998). Untersuchung blutchemischer Parameter bei Heimtierkaninchen.
[Examination of chemical parameters in the serum of pet rabbits.] Kleintierpraxis
43 (6): 447-448, 450-452, ISSN: 0023-2076.
Keywords: healthy pet
rabbits, blood serum, blood chemistry, urea, creatinine, alkaline phosphatase,
parasites, immunodiagnosis, electrolytes, enzymes, urea, creatinine, blood
sugar, alkaline phosphatase, protozoal infections, Encephalitozoon cuniculi,
German language.
Fehr, M. (2002). Nyulak,
tengerimalacok, kisrágcsálók és hüllo k állatvédelmi követelményeknek megfelelo
eutanáziája. [Euthanasia of rabbits, guineapigs, rodents and reptiles,
respecting animal welfare requirements.] Magyar Állatorvosok Lapja
124 (5): 307-311, ISSN: 0025-004X.
NAL Call Number: 41.8 V644
Keywords: guineapigs, mice,
rabbits, rats, reptiles, animal welfare, euthanasia, Hungarian language.
Fehr, M. (2002). Tierschutzgerechte
Euthanasie bei Kaninchen, Meerschweinchen, kleinen Nagern und Reptilien. [Humane
euthanasia of rabbits, rodents and reptiles.] Praktische Tierarzt 83 (2): 128-135,
ISSN: 0032-681X.
NAL Call Number: 41.8 P882
Keywords: rabbits,
reptiles, rodents, animal welfare, euthanasia, techniques, German language.
Forcada, F.; Lopez, M.
(2000). Repeated surgical embryo recovery and embryo production in rabbits. Animal
Reproduction Science 64 (1-2): 121-126, ISSN: 0378-4320.
NAL Call Number: QP251.A5
Keywords: breed, Gigante de
Espana, doe, embryo, female, gonadotropin releasing hormone, corpora lutea,
endocrine system, reproductive system, oviduct, intramuscular injection,
repeated surgical embryo recovery, experimental method, surgical method, embryo
production, ovulation.
Fukase, T. (1998). Pets.
22. Rabbits clinical (part IV). Journal of Veterinary Medicine 51 (5):
383-384, ISSN: 0447-0192.
Keywords: rabbit diseases,
parasitoses, Eimeria, Passalurus ambiguus, Cheyletiella, mites, Japanese
language.
Girling, S.J. (2002). Mammalian
imaging and anatomy. In: BSAVA Manual of Exotic Pets, Meredith, A.;
Redrobe, S. (Eds.), 4th ed., pp. 1-12, British Small Animal
Veterinary Association: Quedgeley, UK, ISBN: 0-905214-47-1.
NAL Call Number: SF981.B78 2002
Keywords: chinchillas,
ferrets, guineapigs, hamsters, rabbits, rats, rodents, anatomy, computed
tomography, diagnostic techniques, laboratory animals, magnetic resonance
imaging, radiography, ultrasonography.
Haffar, A. (1996). La
consultation du lapin de compagnie: examen clinique, contention, prelevement.
[Consultation of the pet rabbit: clinical examination, restraint.] Le
Point Veterinaire 28 (178): 55-61, ISSN: 0335-4997.
NAL Call Number: SF602.P6
Keywords: pets, physiology,
health, diagnosis, veterinary medicine, French language.
Halliday, L.C.; Artwohl,
J.E.; Hanly, W.C.; Bunte, R.M.; Bennett, B.T. (2000). Physiologic and
behavioral assessment of rabbits immunized with Freund’s complete
adjuvant. Contemporary Topics in
Laboratory Animal Science 39 (5): 8-13.
NAL Call Number: SF405.5
A23
Abstract: Although the use
of Freund's Complete Adjuvant (FCA) has been discouraged for the production of
polyclonal antibodies, little clinical evidence supports the belief that FCA
necessarily affects the well-being of immunized rabbits. We designed the
present study to determine whether immunization at multiple sites with small
volumes of Freund's adjuvant affects rabbit well-being. We injected 18 female
New Zealand White rabbits (six animals per group) with antigen in FCA, Freund's
Incomplete Adjuvant, or physiologic saline in the following volumes and routes:
0.02 to 0.03 mL intradermally in each of 30 to 40 sites and 0.1 mL
subcutaneously in each of two sites. The body weight, temperature, complete
blood count, and behavior of the rabbits in the home cage, upon handling, and
in an open field did not differ significantly among the immunization groups
during the 7-week assessment period. Only the degree of induration around
injection sites differed: as expected, FCA induced the greatest response at the
injection sites, but the sites were neither ulcerative nor necrotic, nor did
palpation of the sites induce any apparent discomfort to the rabbits. We
conclude that FCA may be used safely and humanely in rabbits if small volumes
are injected intradermally or subcutaneously in multiple sites.
Keywords: animal welfare,
behavior, physiology, blood cell count, body temperature, body weight, Freund’s
adjuvant, administration and dosage, adverse effects, immunology, heat shock
proteins, histocytochemistry, immunization, intradermal injections,
subcutaneous injections, kidney pathology, liver pathology, lung pathology,
muramidase.
Hartmann, K.; Fischer, S.;
Kraft, W. (1995). Heimtiere als Patienten in der Kleintierpraxis. Teil 2.
Handhabung, Geschlechtsbestimmung, Blutentnahme, Medikamentenapplikation.
[Small pet animals as patients in veterinary practice. Part 2. Handling, sex
determination, blood collection, drug application.] Tieraerztliche
Praxis 23 (1): 83-91, ISSN: 0303-6286.
Keywords: rabbits, gerbils,
guineapigs, hamsters, chinchillas, pets, sampling, blood, application methods,
drugs, sex, handling, German language.
Harvey, S.B.; Hatley, C.L.;
Holmes, R.L.; Runner, R.R.; Tonry, L.L.; McPherson, J.C. (2001). Adaptation
of a dental RadioVisioGraph unit as a laboratory animal research tool. Contemporary
Topics in Laboratory Animal Science 40 (6) :37-40, ISSN: 1060-0558.
NAL Call Number: SF405.5
A23
Abstract: We have adapted
the RadioVisioGraph (RVG), a digital radiography system designed for dentistry,
to become a versatile research tool in a small research facility. We have used
this modified digital imaging system in our institution to assess bone
fractures and ossification in rabbit tibias in which titanium posts were placed
in close proximity to one another, to evaluate bone fill in rats with
experimental cranial critical-size defects, and to ensure the proper placement
of oral gavage tubes in rodents. This method provides instantaneous digital
radiographs, thus not requiring a dedicated X-ray suite or film-processing
equipment, and reduces scatter radiation by < or =95%. The use of this
technology in a small research facility has greatly improved the quality of
both the care our animals receive and the research data we obtain.
Keywords: rabbits, rats,
animal welfare, bone, radiography, equipment design, injuries, dental, tibial
fractures, digital.
Hauer, P.J.; Clough, N.E.
(1999). Development of monoclonal antibodies suitable for use in antigen
quantification potency tests for clostridial veterinary vaccines. Developments
in Biological Standardization 101: 85-94, ISSN: 0301-5149.
NAL Call Number:
QR180.3.D4
Abstract: The quality control
testing of clostridial veterinary vaccines currently requires large numbers of
animals. Alternative in vitro test methods are being investigated by
researchers in industry and by regulatory authorities in many countries.
Monoclonal antibodies that neutralize Clostridium perfringens alpha toxin, C.
perfringens beta toxin, C. perfringens epsilon toxin, and C. sordellii lethal
toxin as well as a monoclonal antibody directed against C. chauvoei flagellar
antigen have been developed by the Center for Veterinary Biologics Laboratory
for use in antigen quantification assays. A proposal to create an international
standard collection of clostridial-specific monoclonal antibodies is made.
Keywords: mice, Inbred BALB
C, rabbits, guinea pigs, animal welfare, monoclonal antibodies, therapeutic
use, antigens, bacterial analysis, bacterial toxins, immunology, clostridium,
veterinary, Clostridium perfringens, enzyme-linked immunosorbent assay,
hybridomas, immunoassay methods.
Heard, D.J. (1995). Rabbit
supportive care. Proceedings of the North American Veterinary
Conference 9: 670-671.
NAL Call Number: SF605.N672
Keywords: veterinary
medicine, heart rate and rhythm, blood pressure, hypolemia, intravenous catheterization, intra-osseous
catheterization, electrolytes, blood transfusion, endotoxemia, respiratory
rate, arterial blood gases, endotracheal intubation, nutritional indicators,
dental problems, nasogastric intubation, total parenteral nutrition, product
information.
Hoffmann, J.N.; Steinhagen,
S.; Kast, C.; Scheuber, H.P.; Jochum, M.; Gippner-Steppert, C.; Inthorn, D.;
Schildberg, F.W.; Nolte, D. (2002). Chronic left heart catheterization for
microvascular blood flow determination in the rabbit: a minimally invasive
technique using specially designed port devices. The Journal of Surgical
Research 102 (2): 119-25, ISSN: 0022-4804.
Abstract: This study
describes a modified catheterization technique with subcutaneously implanted
port catheters to be inserted in a retrograde manner across the aortic valve
into the left heart ventricle through the right carotid artery to measure organ
perfusion. MATERIALS AND METHODS: The specially designed arterial port
catheters were implanted in New Zealand rabbits (n = 11, 3.7 +/- 0.1 kg [mean +/-
SEM]) under iv anesthesia (medetomidine/ketamine) and single-shot perioperative
antibiotic therapy. Hemodynamics were registered continuously during the
operation via an ear artery catheter. RESULTS: Implantation of ports was
performed in all animals (11/11) without major complications (mean operation
time: 70 +/- 3 min). We did not observe catheter-associated arrhythmia, fall in
mean arterial pressure (MAP before and post OP: 70 +/- 2 and 68 +/- 2 Torr,
respectively), or change in arterial oxygen saturation (SaO2 before and post
OP: 89 +/- 3 and 95 +/- 2%, respectively). With a specifically modified
microsurgical insertion technique, cerebral blood supply was effectively
preserved as evidenced from postmortem histological examinations, cerebral
blood flow determination with fluorescent microspheres, and measurement of
S-100b protein serum concentrations, a specific marker of neuronal damage. The
positioning of the catheter tip in the left ventricle was found to be correct
in 10/11 animals. CONCLUSIONS: Repeated and a traumatic microsphere injections
into the left ventricle have become feasible by transcutaneous puncture of
subcutaneous port systems over several weeks under light sedation. Hence, this
new approach (i) avoids the necessity of repeated intracardiac injections and
port insertions via thoracotomy, thus reducing the perioperative stress for the
animals, and (ii) allows for the first time minimally invasive repetitive and
chronic measurements of regional organ blood flow under various experimental settings.
Keywords: breed, New
Zealand, catheterization technique, aortic valve, left heart ventricle, right
carotid artery, organ perfusion, hemodynamics, perioperative stress reduction.
Kelleher, S.A. (2003). Surgical
considerations. In: Scientific Proceedings Veterinary Programme: British
Small Animal Veterinary Association 46th Annual Congress, Birmingham, UK, April
3-6, 2003, Coles, G.; Dobson, J.; Elliott, J.; Elwood, C. (Eds.), British
Small Animal Veterinary Association: Quedgeley, UK, pp. 503-508, ISBN:
0-905214-77-3.
Keywords: abscesses,
anesthesia, castration, entropion, enucleation, fracture fixation, ovariectomy,
preoperative care, surgery, surgical operations, wound treatment.
Kiwull, S.H.; Kalhoff, H.;
Manz, F.; Diekmann, L.; Kiwull, P. (2001). Minimal-invasive approach to
study pulmonary, metabolic and renal responses to alimentary acid-base changes
in conscious rabbits. European Journal of Nutrition 40 (5): 255-259,
ISSN: 1436-6207.
NAL Call Number:
QP141.A1E97
Keywords: carbonic
anhydrase, alimentary acid base load analysis, analytical method, minimal
invasive, nutritional method, physiological method, food mineral content,
nutrition, rabbit chow, respiratory control.
Malley, A.D.; Hage, M.H.
van der (1996). The pet rabbit in companion animal practice. 6. Necropsy
procedure. Irish Veterinary Journal 49 (8): 488-490, ISSN: 0368-0762.
NAL Call Number: 41.8 IR4
Keywords: pets, postmortem
examinations, diagnosis, rabbit diseases.
Malley, A.D. (1996). The
pet rabbit in companion animal practice. 4. Haematological and biochemical
reference values. Irish Veterinary Journal 49 (6): 354-358, ISSN:
0368-0762.
NAL Call Number: 41.8 IR4
Keywords: pets, hematology,
blood chemistry.
Malley, A.D. (1995). The
pet rabbit in companion animal practice. 2. General clinical examination. Irish
Veterinary Journal 48 (9): 307-311, ISSN: 0368-0762.
NAL Call Number: 41.8 IR4
Keywords: handling,
restraint, small animal practice, veterinary practice, pets, fractures,
lacrimal apparatus, skin, thorax, abdomen, mouth, limbs, diagnostic techniques,
clinical examination.
Malley, A.D. (1996). The
pet rabbit in companion animal practice. 3. Special examinations. Irish
Veterinary Journal 49 (2): 112-114, ISSN: 0368-0762.
NAL Call Number: 41.8 IR4
Keywords: pets, sex
determination, pregnancy diagnosis, blood specimen collection, radiography,
pathology.
Malley, A.D. (1996). The
pet rabbit in companion animal practice. 5. The administration of medication. Irish
Veterinary Journal 49 (7): 407-410, ISSN: 0368-0762.
NAL Call Number: 41.8 IR4
Keywords: pets, drug
therapy, application methods, injection, topical application.
Meredith, A.; Redrobe, S.
(2002). BSAVA Manual of Exotic Pets, Meredith, A.; Redrobe, S.
(Eds.), 4th ed., 304 p., British Small Animal Veterinary Association:
Quedgeley, UK, ISBN: 0-905214-47-1.
NAL Call Number: SF981.B78
2002
Keywords: pets, ornamental
fishes, aviary birds, amphibia, birds, chinchillas, ferrets, gerbils,
guineapigs, hamsters, lizards, mice, pigeons, rabbits, rats, snakes, tortoises,
turtles, anesthesia, anatomy, diseases, husbandry, diagnosis, diagnostic
techniques, drug therapy, euthanasia, exotics, handbooks, restraint of animals,
surgical operations.
Morton, D.B.; Jennings, M.;
Buckwell, A.; Ewbank, R.; Godfrey, C.; Holgate, B.; Inglis, I.; James, R.;
Page, C.; Sharman, I.; Verschoyle, R.; Westall, L.; Wilson, A.B. (2001). Refining
procedures for the administration of substances: Report of the
BVAAWF/FRAME/RSPCA /UFAW Joint Working Group on Refinement. Laboratory
Animals 35 (1): 1-41, ISSN: 0023-6772.
NAL Call Number: QL55.A1L3
Keywords: cat, dog, ferret,
guineapig, hamster, mouse, primate, rabbit, rat, sheep, footpad, British
Veterinary Association Animal Welfare Foundation [BVAAWF], Royal Society for
the Prevention of Cruelty to Animals [RSPCA], Universities Federation for Animal
Welfare [UFAW], administration route, intra articular administration, drug
delivery method, intracerebral administration, intradermal administration,
intramuscular administration, intranasal administration, intraperitoneal
administration, intratracheal administration, intravaginal administration,
intravenous administration, oral administration, osmotic minipumps, refining
procedures, laboratory method, respiratory administration, subcutaneous
administration, topical administration, Fund for the Replacement of Animals in
Medical Experiments [FRAME], animal suffering, distress, good practice, pain,
substance administration.
Mrozek, M. (1995). Microchip
implant system used for animal identification in laboratory rabbits,
guineapigs, woodchucks and in amphibians. Laboratory Animals London
29 (3): 339-344, ISSN: 0023-6772.
NAL Call Number: QL55.A1L3
Keywords: rabbits, guineapigs, Marmota monax.
Orcutt, C.J. (2001). Fluids
and critical care in small mammals. Proceedings of the North American
Veterinary Conference 15:
886-887. In the volume: Small Animal and Exotics. Part of a three
volume set. Meeting held January 13-17, 2001 in Orlando, Florida.
NAL Call Number: SF605.N672
Keywords: fluid therapy,
catheter placement, fluid maintenance, nutrition, pain management, gastric
obstruction, endotracheal intubation.
Perdue, K.A.; Shaw, R.E.;
Mage, R.G. (2000). Declawing of neonatal rabbits destined for use in animal
biosafety level 4 containment studies. Contemporary Topics in Laboratory
Animal Science 39 (3): 13-18, ISSN: 1060-0558.
NAL Call Number: SF405.5.A23
Keywords: laboratory
animals, declawing, scratch prevention, human safety, Biosafety Level 4.
Quesenberry, K. (1998). Ferrets,
rabbits, and rodents: basic medical management and clinical techniques. Parts I
and II. In: Internal Medicine: Small Companion Animals. The T G
Hungerford Course for Veterinarians. Proceedings 306, Stephen Roberts Lecture
Theatre, University of Sydney, Australia, June 15 -19, 1998, Bryden, D.
(Ed.), pp. 41-51. University of Sydney, Post Graduate Foundation in Veterinary
Science: Sydney, Australia. ISBN: 1-875582-69-X.
NAL Call Number: SF604.R37
no. 306
Keywords: ferrets, rabbits,
rodents, guineapigs, small animal practice, diagnosis, diagnostic techniques,
therapy, drug therapy, clinical examination.
Thunder, R.M. (1998). A
method for immobilizing the forelimbs of rabbits. Contemporary Topics in
Laboratory Animal Science 37 (5): 94-95, ISSN: 1060-0558.
NAL Call Number: SF405.5.A23
Keywords: legs, tendons,
postoperative care, casts.
Tran, H.S. (2001). A
method of endoscopic endotracheal intubation in rabbits. Laboratory
Animals 35 (3): 249-252, ISSN: 0023-6772.
NAL Call Number: QL55.A1L3
Keywords: laboratory
mammals, endoscopy, endoscopes, trachea.
Willard, M.D.; Tvedten, H.
(2004). Small Animal Clinical Diagnosis by Laboratory Methods. 4th
ed., W.B. Saunders, 448 p. ISBN: 0721689035.
NAL Call Number: SF991.S59
2004
Keywords: laboratory tests,
techniques, interpretation, blood count and bone marrow examination,
erythrocyte, leukocyte disorders, hemostatic abnormalities, serum chemistries,
point of care instruments, electrolyte and acid-based disorders, urinary
disorders, endocrine, metabolic, and lipid disorders, gastrointestinal disorders,
fluid accumulation disorders, respiratory disorders, immunologic disorders,
reproductive disorders, neurologic disorders, infectious disease, cytology of
neoplastic and inflammatory masses, diagnostic toxicology, therapeutic drug
monitoring appendices, listing of referral laboratories, reference values,
color illustrations, appendices, tables.
Wolvekamp, W.T.C. (1996). Radiology
of exotic pets (small mammals, birds, and reptiles). Veterinary
Quarterly 18 (Supp1.): S52-S54, ISSN: 0165-2176.
NAL Call Number: SF601.V46
Keywords: pets, diagnosis,
radiography, poultry, rodents, mammals, birds, reptiles, guineapigs, rabbits,
pigeons.
Worthley, S.G. (2000). Rapid
oral endotracheal intubation with a fibre-optic scope in rabbits: a simple and
reliable technique. Laboratory Animals 34 (2): 199-201. ISSN:
0023-6772.
NAL Call Number: QL55.A1L3
Keywords: animal welfare,
anesthesia, inhaled anesthetics.
Yates, D.W. (1996). Comparative
study of two techniques of long-term venous catheterization in rabbits: matching
methods to applications. Contemporary Topics in Laboratory Animal
Science 35 (3): 63-68, ISSN: 1060-0558.
NAL Call Number: SF405.5.A23
Keywords: laboratory
mammals, catheterization.