National Guidance

Guidance for Assessing Chemical Contaminant Data for Use In Fish Advisories

Volume 2: Risk Assessment and Fish Consumption Limits - Third Edition

SECTION

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• Figures
• Tables
• Acknowledgements (PDF, 8K)
• Acronyms (PDF, 15K)


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  • Cover Page (PDF, 92K)
    
  • Table of Contents (PDF, 42K)
    
  • Executive Summary (PDF, 19K)

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  1.		Introduction (PDF, 56K)
  2.		Risk Assessment Methods (PDF, 345K)
  		2.1		Introduction
  		2.2		Hazard Identification
  		2.3		Dose-Response Assessment
  		2.4		Exposure Assessment
  		2.5		Risk Characterization
  		2.6		Summarizing Risk Data
  3.		Development and Use of Risk-Based Consumption Limits (PDF, 122K)
  		3.1		Overview and Section Organization
  		3.2		Equations Used to Develop Risk-Based Consumption Limits
  		3.3		Default and Alternative Values for Calculating Consumption Limits
  		3.4		Modification of Consumption Limits for a Single Contaminant in a Multispecies Diet
  		3.5		Modification of Consumption Limits for Multiple Contaminant Exposures
  4.		Risk-Based Consumption Limit Tables (PDF, 71K)
  		4.1		Overview & Section Organization
  		4.2		Consumption Limit Tables
  5.		Toxicological Profile Summaries for Target Analytes (PDF, 357K)
  		5.1		Introduction
  		5.2		Metals
  		5.3		Organochlorine Pesticides
  		5.4		Organophosphate Pesticides
  		5.5		Chlorophenoxy Herbicides
  		5.6		Polycyclic Aromatic Hydrocarbons (PAHs)
  		5.7		Polychlorinated Biphenyls (PCBs)
  		5.8		Dioxins
  6.		Mapping Tools for Risk Assessment and Risk Management (PDF, 323K)
  7.		Literature Cited (48 KB)

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  Appendix
  A		Reviewers of First Edition of Guidance Document (PDF, 12K)
  B		Population Exposure Assessment & Consumption Patterns and Surveys (PDF, 132K)
  C		Dose Modification Due to Food Preparation and Cooking (PDF, 90K)
  D		Guidance for Risk Characterization (PDF, 122K)
  E		Additional Developmental toxicity Issues (PDF, 28K)
  F		Summary of Limits of Detection for the Recommended Target Analytes (PDF, 15K)

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  List of Figures
  1-1		Series Summary: Guidance for Assessing Chemical Contamination Data for Use in Fish Advisories
  2-1		Elements or Risk assessment and risk management
  2-2		Schematic of exposure categories in upper half of a normal population distribution
  6-1		GIS Data Layers may use raster or vector Representation techniques
  6-2		Examples of GIS Displays from EPA's BASINInfo Maps-on-Demand Facility
  6-3		Map showing active fish and wildlife advisories for a state

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  List of Tables
  1-1		Target Analytes Recommended for Fish Sampling Programs
  1-2		Comparison of FDA Action Levels and Tolerances with EPA Screening Values
  1-3		Fish Consumption Rates for Various Fisher Populations
  2-1		Uncertainty Factors and Modifying Factors for Estimating Exposure Limits for Chronic Effects
  2-2		Mean Body Weights of Children and Adults
  2-3		Categories of Information Necessary for a Population Exposure Assessment
  2-4		Exposure Data Template
  2-5		Risk Estimates
  2-6		Risk Characterization
  2-7		Risk Summaries for a Waterbody
  2-8		Risk Summaries for a Geographic Area
  3-1		Risk Values Used in Risk-Based Consumption Limit Tables
  3-2		Input Parameters for Use in Risk Equations
  3-3		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints & Chlordane
  3-4		Monthly Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints- Chlordane
  3-5		Average Body Weights and Associated Multipliers
  4-1		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Arsenic
  4-2		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Cadmium
  4-3		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Methlymercury
  4-4		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Selenium
  4-5		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Tributyltin
  4-6		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Chlordane
  4-7		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - DDT
  4-8		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Dicofol
  4-9		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints -Dieldrin
  4-10		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Endosulfan
  4-11		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Endrin
  4-12		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Heptachlor Epoxide
  4-13		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Hexachlorobenzene
  4-14		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Lindane
  4-15		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Mirex
  4-16		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - Toxaphene
  4-17		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Chlorpyrifos
  4-18		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Diazinon
  4-19		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Disulfoton
  4-20		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Ethion
  4-21		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Terbufos
  4-22		Monthly Fish Consumption Limits for Noncarcinogenic Health Endpoint - Oxyfluorfen
  4-23		Monthly Fish Consumption Limits for Carcinogenic Health Endpoint - PAHs
  4-24		Monthly Fish Consumption Limits for Carcinogenic and Noncarcinogenic Health Endpoints - PCBs
  4-25		Monthly Fish Consumption Limits for Carcinogenic Health Endpoint - Dioxins/Furans
  5-1		Health and Toxicological Data Reviewed for Target Analytes
  5-2		Toxicity Equivalent Factors for Various PAHs
  5-3		Relative Potency Estimates for Various PAHs
  5-4		Reported Concentrations (ppm) of Dioxin-Like Congeners in Commercial Aroclor Mixtures
  5-5		PCB and Dioxin Concentrations (ppb) in Channel Catfish
  6-1		Comparison of Raster- Versus Vector-Based GIS Programs

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