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Volume 8;  2008
Correspondence
Time esophageal pH < 4 overestimates the prevalence of pathologic esophageal reflux in subjects with gastroesophageal reflux disease treated with proton pump inhibitors
Lauren B Gerson, George Triadafilopoulos, Peyman Sahbaie, Winston Young, Sheldon Sloan, Malcolm Robinson, Philip B Miner, Jr, and Jerry D Gardner
BMC Gastroenterol. 2008; 8: 15. Published online 2008 May 23. doi: 10.1186/1471-230X-8-15.
PMCID: PMC2409349
Study Protocol
Risk factors associated with non-alcoholic fatty liver disease in subjects from primary care units. A case-control study
Llorenç Caballería, Ma Antonia Auladell, Pere Torán, Guillem Pera, Dolores Miranda, Alba Alumà, José Dario Casas, Laura Muñoz, Carmen Sanchez, Albert Tibau, Marti Birules, Santiago Canut, Jesús Bernad, Josep Aubà, Miren Maite Aizpurua, and Enriqueta Alcaraz
BMC Gastroenterol. 2008; 8: 44. Published online 2008 October 3. doi: 10.1186/1471-230X-8-44.
PMCID: PMC2569953
Research Articles
Multilayered epithelium in a rat model and human Barrett's esophagus: Similar expression patterns of transcription factors and differentiation markers
Xiaoxin Chen, Rong Qin, Ba Liu, Yan Ma, Yinghao Su, Chung S Yang, Jonathan N Glickman, Robert D Odze, and Nicholas J Shaheen
BMC Gastroenterol. 2008; 8: 1. Published online 2008 January 11. doi: 10.1186/1471-230X-8-1.
PMCID: PMC2267197
Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron
Donald J Messner and Kris V Kowdley
BMC Gastroenterol. 2008; 8: 2. Published online 2008 February 6. doi: 10.1186/1471-230X-8-2.
PMCID: PMC2275280
Alcoholic cirrhosis in Denmark – population-based incidence, prevalence, and hospitalization rates between 1988 and 2005: A descriptive cohort study
Peter Jepsen, Hendrik Vilstrup, and Henrik T Sørensen
BMC Gastroenterol. 2008; 8: 3. Published online 2008 February 9. doi: 10.1186/1471-230X-8-3.
PMCID: PMC2275281
Bile reflux index after therapeutic biliary procedures
Sedef Kuran, Erkan Parlak, Gulden Aydog, Sabite Kacar, Nurgul Sasmaz, Ali Ozden, and Burhan Sahin
BMC Gastroenterol. 2008; 8: 4. Published online 2008 February 11. doi: 10.1186/1471-230X-8-4.
PMCID: PMC2257961
Epidemiology of constipation in Europe and Oceania: a systematic review
George Peppas, Vangelis G Alexiou, Eleni Mourtzoukou, and Matthew E Falagas
BMC Gastroenterol. 2008; 8: 5. Published online 2008 February 12. doi: 10.1186/1471-230X-8-5.
PMCID: PMC2258300
Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis
Minghua Zheng, Jianling Bai, Bosi Yuan, Feng Lin, Jie You, Mingqin Lu, Yuewen Gong, and Yongping Chen
BMC Gastroenterol. 2008; 8: 6. Published online 2008 February 14. doi: 10.1186/1471-230X-8-6.
PMCID: PMC2258301
Gastrointestinal symptoms and motility disorders in patients with systemic scleroderma
Agostino Di Ciaula, Michele Covelli, Massimo Berardino, David QH Wang, Giovanni Lapadula, Giuseppe Palasciano, and Piero Portincasa
BMC Gastroenterol. 2008; 8: 7. Published online 2008 February 27. doi: 10.1186/1471-230X-8-7.
PMCID: PMC2276219
A self administered reliable questionnaire to assess lower bowel symptoms
Barbara-Ann Adelstein, Les Irwig, Petra Macaskill, Peter H Katelaris, David B Jones, and Les Bokey
BMC Gastroenterol. 2008; 8: 8. Published online 2008 March 1. doi: 10.1186/1471-230X-8-8.
PMCID: PMC2311315
Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa
Hanna Haveri, Mia Westerholm-Ormio, Katri Lindfors, Markku Mäki, Erkki Savilahti, Leif C Andersson, and Markku Heikinheimo
BMC Gastroenterol. 2008; 8: 9. Published online 2008 April 11. doi: 10.1186/1471-230X-8-9.
PMCID: PMC2323380
Inverse association between gastroesophageal reflux and blood pressure: Results of a large community based study
Liam J Murray, Peter McCarron, Roger B McCorry, Lesley A Anderson, Athene J Lane, Brian T Johnston, George Davey Smith, and Richard F Harvey
BMC Gastroenterol. 2008; 8: 10. Published online 2008 April 15. doi: 10.1186/1471-230X-8-10.
PMCID: PMC2330142
Effects of pectin liquid on gastroesophageal reflux disease in children with cerebral palsy
Reiko Miyazawa, Takeshi Tomomasa, Hiroaki Kaneko, Hirokazu Arakawa, Nobuzo Shimizu, and Akihiro Morikawa
BMC Gastroenterol. 2008; 8: 11. Published online 2008 April 16. doi: 10.1186/1471-230X-8-11.
PMCID: PMC2383913
Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding
Hiroki Endo, Nobuyuki Matsuhashi, Masahiko Inamori, Keiko Akimoto, Tomohiko Ohya, Tatsuro Yanagawa, Masako Asayama, Kantaro Hisatomi, Takuma Teratani, Koji Fujita, Masato Yoneda, and Atsushi Nakajima
BMC Gastroenterol. 2008; 8: 12. Published online 2008 April 23. doi: 10.1186/1471-230X-8-12.
PMCID: PMC2447670
Prevalence and determinants of biochemical dysfunction of the liver in Atayal Aboriginal community of Taiwan: Is betel nut chewing a risk factor?
Ching-Feng Lin, Tun-Jen Shiau, Ying-Chin Ko, Ping-Ho Chen, and Jung-Der Wang
BMC Gastroenterol. 2008; 8: 13. Published online 2008 April 27. doi: 10.1186/1471-230X-8-13.
PMCID: PMC2443869
Total and caspase-cleaved cytokeratin 18 in chronic cholecystitis: A prospective study
Constantinos Simopoulos, Alexandra K Tsaroucha, Byron Asimakopoulos, Alexandra Giatromanolaki, Paschalis Gavriilidis, Alexandros Polychronidis, and Anastasios Karayiannakis
BMC Gastroenterol. 2008; 8: 14. Published online 2008 May 6. doi: 10.1186/1471-230X-8-14.
PMCID: PMC2396167
Liver cirrhosis, other liver diseases, and risk of hospitalisation for intracerebral haemorrhage: A Danish population-based case-control study
Henning Grønbæk, Søren P Johnsen, Peter Jepsen, Mette Gislum, Hendrik Vilstrup, Ulrik Tage-Jensen, and Henrik T Sørensen
BMC Gastroenterol. 2008; 8: 16. Published online 2008 May 24. doi: 10.1186/1471-230X-8-16.
PMCID: PMC2413247
Senescence marker protein 30 in acute liver failure: validation of a mass spectrometry proteomics assay
Sa Lv, Jiang-hua Wang, Feng Liu, Yan Gao, Ran Fei, Shao-cai Du, and Lai Wei
BMC Gastroenterol. 2008; 8: 17. Published online 2008 May 28. doi: 10.1186/1471-230X-8-17.
PMCID: PMC2435529
Absence of gastrointestinal infections in a cohort of patients with Zollinger-Ellison syndrome and other acid hypersecretors receiving long-term acid suppression with lansoprazole
C Mel Wilcox, Toni Martin, Milind Phadnis, Jean Mohnen, Julie Worthington, and Basil I Hirschowitz
BMC Gastroenterol. 2008; 8: 18. Published online 2008 May 28. doi: 10.1186/1471-230X-8-18.
PMCID: PMC2414526
Influence of acute pancreatitis on the in vitro responsiveness of rat mesenteric and pulmonary arteries
Enilton A Camargo, Maria Andréia Delbin, Tatiane Ferreira, Elen CT Landucci, Edson Antunes, and Angelina Zanesco
BMC Gastroenterol. 2008; 8: 19. Published online 2008 May 29. doi: 10.1186/1471-230X-8-19.
PMCID: PMC2435530
Short-term triple therapy with azithromycin for Helicobacter pylori eradication: Low cost, high compliance, but low efficacy
Fernando M Silva, Jaime N Eisig, Ana Cristina S Teixeira, Ricardo C Barbuti, Tomás Navarro-Rodriguez, and Rejane Mattar
BMC Gastroenterol. 2008; 8: 20. Published online 2008 May 29. doi: 10.1186/1471-230X-8-20.
PMCID: PMC2438368
Changes in the gastric enteric nervous system and muscle: A case report on two patients with diabetic gastroparesis
Pankaj J Pasricha, Nonko D Pehlivanov, Guillermo Gomez, Harsha Vittal, Matthew S Lurken, and Gianrico Farrugia
BMC Gastroenterol. 2008; 8: 21. Published online 2008 May 30. doi: 10.1186/1471-230X-8-21.
PMCID: PMC2442096
Combined written and oral information prior to gastrointestinal endoscopy compared with oral information alone: a randomized trial
Christian Felley, Thomas V Perneger, Isabelle Goulet, Catherine Rouillard, Nadereh Azar-Pey, Gian Dorta, Antoine Hadengue, and Jean-Louis Frossard
BMC Gastroenterol. 2008; 8: 22. Published online 2008 June 3. doi: 10.1186/1471-230X-8-22.
PMCID: PMC2430967
Symptoms of gastroesophageal reflux disease in severely mentally retarded people: a systematic review
Anke JE de Veer, Judith T Bos, Riet C Niezen-de Boer, Clarisse JM Böhmer, and Anneke L Francke
BMC Gastroenterol. 2008; 8: 23. Published online 2008 June 11. doi: 10.1186/1471-230X-8-23.
PMCID: PMC2435531
The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine
Charles E Patek, Mark J Arends, Lorraine Rose, Feijun Luo, Marion Walker, Paul S Devenney, Rachel L Berry, Nicola J Lawrence, Rachel A Ridgway, Owen J Sansom, and Martin L Hooper
BMC Gastroenterol. 2008; 8: 24. Published online 2008 June 13. doi: 10.1186/1471-230X-8-24.
PMCID: PMC2442095
Quality of health care and patient satisfaction in liver disease: The development and preliminary results of the QUOTE-Liver questionnaire
Jolie J Gutteling, Robert A de Man, Jan JV Busschbach, and Anne-Sophie E Darlington
BMC Gastroenterol. 2008; 8: 25. Published online 2008 June 20. doi: 10.1186/1471-230X-8-25.
PMCID: PMC2453127
Rifaximin for maintenance therapy in antibiotic-dependent pouchitis
Bo Shen, Feza H Remzi, A Rocio Lopez, and Elaine Queener
BMC Gastroenterol. 2008; 8: 26. Published online 2008 June 23. doi: 10.1186/1471-230X-8-26.
PMCID: PMC2442097
Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
Masato Yoneda, Kikuko Hotta, Yuichi Nozaki, Hiroki Endo, Takashi Uchiyama, Hironori Mawatari, Hiroshi Iida, Shingo Kato, Kunihiro Hosono, Koji Fujita, Kyoko Yoneda, Hirokazu Takahashi, Hiroyuki Kirikoshi, Noritoshi Kobayashi, Masahiko Inamori, Yasunobu Abe, Kensuke Kubota, Satoru Saito, Shiro Maeyama, Koichiro Wada, and Atsushi Nakajima
BMC Gastroenterol. 2008; 8: 27. Published online 2008 June 27. doi: 10.1186/1471-230X-8-27.
PMCID: PMC2453128
Unexplained chest/epigastric pain in patients with normal endoscopy as a predictor for ischemic heart disease and mortality: A Danish 10-year cohort study
Estrid Muff Munk, Bente Nørgård, Claus Dethlefsen, Hans Gregersen, Asbjørn Mohr Drewes, Peter Funch-Jensen, and Henrik Toft Sørensen
BMC Gastroenterol. 2008; 8: 28. Published online 2008 July 15. doi: 10.1186/1471-230X-8-28.
PMCID: PMC2490769
Wilson protein expression, copper excretion and sweat production in sweat glands of Wilson disease patients and controls
Mark Schaefer, Mavi Schellenberg, Uta Merle, Karl Heinz Weiss, and Wolfgang Stremmel
BMC Gastroenterol. 2008; 8: 29. Published online 2008 July 17. doi: 10.1186/1471-230X-8-29.
PMCID: PMC2515315
Evaluation of the Birmingham IBS symptom questionnaire
Andrea K Roalfe, Lesley M Roberts, and Sue Wilson
BMC Gastroenterol. 2008; 8: 30. Published online 2008 July 23. doi: 10.1186/1471-230X-8-30.
PMCID: PMC2496907
Caustic ingestion in adults: The role of endoscopic classification in predicting outcome
Hao-Tsai Cheng, Chi-Liang Cheng, Cheng-Hui Lin, Jui-Hsiang Tang, Yin-Yi Chu, Nai-Jen Liu, and Pang-Chi Chen
BMC Gastroenterol. 2008; 8: 31. Published online 2008 July 25. doi: 10.1186/1471-230X-8-31.
PMCID: PMC2533005
Hospital-acquired invasive pulmonary aspergillosis in patients with hepatic failure
Dan Li, Liang Chen, Xian Ding, Ran Tao, Yong Xin Zhang, and Jie Fei Wang
BMC Gastroenterol. 2008; 8: 32. Published online 2008 July 31. doi: 10.1186/1471-230X-8-32.
PMCID: PMC2516516
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy
Tae-Bum Lee, Jung-Hee Park, Young-Don Min, Kyung-Jong Kim, and Cheol-Hee Choi
BMC Gastroenterol. 2008; 8: 33. Published online 2008 August 1. doi: 10.1186/1471-230X-8-33.
PMCID: PMC2529328
Five mucosal transcripts of interest in ulcerative colitis identified by quantitative real-time PCR: a prospective study
Anders Eriksson, Carl-Fredrik Flach, Anders Lindgren, Eva Kvifors, and Stefan Lange
BMC Gastroenterol. 2008; 8: 34. Published online 2008 August 12. doi: 10.1186/1471-230X-8-34.
PMCID: PMC2531169
Immunohistochemical testing for Helicobacter Pylori existence in neoplasms of the colon
Aliye Soylu, Selvinaz Ozkara, Halil Alıs, Kemal Dolay, Mustafa Kalaycı, Nurgul Yasar, and A Baki Kumbasar
BMC Gastroenterol. 2008; 8: 35. Published online 2008 August 14. doi: 10.1186/1471-230X-8-35.
PMCID: PMC2527302
Correlation between CD4 counts of HIV patients and enteric protozoan in different seasons – An experience of a tertiary care hospital in Varanasi (India)
Lekha Tuli, Anil K Gulati, Shyam Sundar, and Tribhuban M Mohapatra
BMC Gastroenterol. 2008; 8: 36. Published online 2008 August 20. doi: 10.1186/1471-230X-8-36.
PMCID: PMC2536662
Validation of a survey methodology for gastroesophageal reflux disease in China
Yang Cao, Xiaoyan Yan, Xiu-Qiang Ma, Rui Wang, Saga Johansson, Mari-Ann Wallander, and Jia He
BMC Gastroenterol. 2008; 8: 37. Published online 2008 August 21. doi: 10.1186/1471-230X-8-37.
PMCID: PMC2533006
Erythromycin lacks colon prokinetic effect in children with functional gastrointestinal disorders: a retrospective study
Narayanan Venkatasubramani, Colin D Rudolph, and Manu R Sood
BMC Gastroenterol. 2008; 8: 38. Published online 2008 August 21. doi: 10.1186/1471-230X-8-38.
PMCID: PMC2529327
Haemodynamic effects of plasma-expansion with hyperoncotic albumin in cirrhotic patients with renal failure: a prospective interventional study
Andreas Umgelter, Katrin Wagner, Wolfgang Reindl, Nils Nurtsch, Wolfgang Huber, and Roland M Schmid
BMC Gastroenterol. 2008; 8: 39. Published online 2008 August 27. doi: 10.1186/1471-230X-8-39.
PMCID: PMC2556671
Resveratrol inhibits nonalcoholic fatty liver disease in rats
Luis Bujanda, Elizabeth Hijona, Mikel Larzabal, Marta Beraza, Pablo Aldazabal, Nerea García-Urkia, Cristina Sarasqueta, Angel Cosme, Belen Irastorza, Alberto González, and Juan I Arenas, Jr
BMC Gastroenterol. 2008; 8: 40. Published online 2008 September 9. doi: 10.1186/1471-230X-8-40.
PMCID: PMC2547101
Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study
Wolfgang Kratzer, Mark M Haenle, Andrea Voegtle, Richard A Mason, Atilla S Akinli, Klaus Hirschbuehl, Andreas Schuler, Volker Kaechele, and the Roemerstein study group
BMC Gastroenterol. 2008; 8: 41. Published online 2008 September 15. doi: 10.1186/1471-230X-8-41.
PMCID: PMC2553794
Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats
Hei Zi-qing, Gan Xiao-liang, Huang Pin-jie, Wei Jing, Shen Ning, and Gao Wan-ling
BMC Gastroenterol. 2008; 8: 42. Published online 2008 September 22. doi: 10.1186/1471-230X-8-42.
PMCID: PMC2564972
The clinical overlap between functional dyspepsia and irritable bowel syndrome based on Rome III criteria
AnJiang WANG, XianHua LIAO, LiShou XIONG, Sui PENG, YingLian XIAO, SiChun LIU, PinJin HU, and MinHu CHEN
BMC Gastroenterol. 2008; 8: 43. Published online 2008 September 23. doi: 10.1186/1471-230X-8-43.
PMCID: PMC2569040
Determinants of female sexual function in inflammatory bowel disease: a survey based cross-sectional analysis
Antje Timmer, Daniela Kemptner, Alexandra Bauer, Angela Takses, Claudia Ott, and Alois Fürst
BMC Gastroenterol. 2008; 8: 45. Published online 2008 October 3. doi: 10.1186/1471-230X-8-45.
PMCID: PMC2571095
Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional study
Evangelos Kalaitzakis, Axel Josefsson, and Einar Björnsson
BMC Gastroenterol. 2008; 8: 46. Published online 2008 October 15. doi: 10.1186/1471-230X-8-46.
PMCID: PMC2575200
Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion
Karan M Emerick, Marc S Elias, Hector Melin-Aldana, Sandra Strautnieks, Richard J Thompson, Laura N Bull, AS Knisely, Peter F Whitington, and Richard M Green
BMC Gastroenterol. 2008; 8: 47. Published online 2008 October 20. doi: 10.1186/1471-230X-8-47.
PMCID: PMC2585081
Bones and Crohn's: Estradiol deficiency in men with Crohn's disease is not associated with reduced bone mineral density
J Klaus, M Reinshagen, G Adler, BO Boehm, and C von Tirpitz
BMC Gastroenterol. 2008; 8: 48. Published online 2008 October 23. doi: 10.1186/1471-230X-8-48.
PMCID: PMC2577678
The Helicobacter pylori duodenal ulcer promoting gene, dupA in China
Zhiyu Zhang, Qing Zheng, Xiaoyu Chen, Shudong Xiao, Wenzhong Liu, and Hong Lu
BMC Gastroenterol. 2008; 8: 49. Published online 2008 October 25. doi: 10.1186/1471-230X-8-49.
PMCID: PMC2584642
Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of coeliac children
Ester Sánchez, Inmaculada Nadal, Ester Donat, Carmen Ribes-Koninckx, Miguel Calabuig, and Yolanda Sanz
BMC Gastroenterol. 2008; 8: 50. Published online 2008 November 4. doi: 10.1186/1471-230X-8-50.
PMCID: PMC2615025
Scintigraphic evaluation of oesophageal transit during radiotherapy to the mediastinum
Giuseppe Sasso, Pierfrancesco Rambaldi, Francesco S Sasso, Vincenzo Cuccurullo, Paola Murino, Paolo Puntieri, Hugo R Marsiglia, and Luigi Mansi
BMC Gastroenterol. 2008; 8: 51. Published online 2008 November 5. doi: 10.1186/1471-230X-8-51.
PMCID: PMC2611991
Predictors of gastrointestinal lesions on endoscopy in iron deficiency anemia without gastrointestinal symptoms
Shahid Majid, Mohammad Salih, Rozina Wasaya, and Wasim Jafri
BMC Gastroenterol. 2008; 8: 52. Published online 2008 November 9. doi: 10.1186/1471-230X-8-52.
PMCID: PMC2613391
Plasma Pentraxin3 is a Novel Marker for Nonalcoholic Steatohepatitis (NASH)
Masato Yoneda, Takashi Uchiyama, Shingo Kato, Hiroki Endo, Koji Fujita, Kyoko Yoneda, Hironori Mawatari, Hiroshi Iida, Hirokazu Takahashi, Hiroyuki Kirikoshi, Masahiko Inamori, Yuichi Nozaki, Noritoshi Kobayashi, Kensuke Kubota, Satoru Saito, Shiro Maeyama, Mina Sagara, Hiroyuki Aburatani, Tatsuhiko Kodama, and Atsushi Nakajima
BMC Gastroenterol. 2008; 8: 53. Published online 2008 November 14. doi: 10.1186/1471-230X-8-53.
PMCID: PMC2621235
Commonly used bowel preparations have significant and different effects upon cell proliferation in the colon: a pilot study
Lisa J Croucher, Jonathan P Bury, Elizabeth A Williams, Stuart A Riley, and Bernard M Corfe
BMC Gastroenterol. 2008; 8: 54. Published online 2008 November 14. doi: 10.1186/1471-230X-8-54.
PMCID: PMC2588612
Imbalance of tissue inhibitors of metalloproteinases (TIMP) – 1 and – 4 serum levels, in patients with inflammatory bowel disease
Andreas N Kapsoritakis, Anastasia I Kapsoritaki, Ioanna P Davidi, Vasilios D Lotis, Anastasios C Manolakis, Petros I Mylonis, Aikaterini T Theodoridou, Anastasios E Germenis, and Spyros P Potamianos
BMC Gastroenterol. 2008; 8: 55. Published online 2008 November 26. doi: 10.1186/1471-230X-8-55.
PMCID: PMC2613880
Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival
Hirozumi Sawai, Akira Yasuda, Nobuo Ochi, Jiachi Ma, Yoichi Matsuo, Takehiro Wakasugi, Hiroki Takahashi, Hitoshi Funahashi, Mikinori Sato, and Hiromitsu Takeyama
BMC Gastroenterol. 2008; 8: 56. Published online 2008 November 26. doi: 10.1186/1471-230X-8-56.
PMCID: PMC2611992
Wnt-reporter expression pattern in the mouse intestine during homeostasis
Paige S Davies, Adria D Dismuke, Anne E Powell, Kevin H Carroll, and Melissa H Wong
BMC Gastroenterol. 2008; 8: 57. Published online 2008 December 2. doi: 10.1186/1471-230X-8-57.
PMCID: PMC2615026
Alcohol consumption is associated with an increased risk of erosive esophagitis and Barrett's epithelium in Japanese men
Tomoyuki Akiyama, Masahiko Inamori, Hiroshi Iida, Hironori Mawatari, Hiroki Endo, Kunihiro Hosono, Kyoko Yoneda, Koji Fujita, Masato Yoneda, Hirokazu Takahashi, Ayumu Goto, Yasunobu Abe, Noritoshi Kobayashi, Kensuke Kubota, Satoru Saito, and Atsushi Nakajima
BMC Gastroenterol. 2008; 8: 58. Published online 2008 December 11. doi: 10.1186/1471-230X-8-58.
PMCID: PMC2615024
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