| | Other Issues: previous | next | latest | archiveCase Report Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration Edward L Tobinick and Hyman Gross PMCID: PMC2211476 Commentary Perispinal etanercept: Potential as an Alzheimer therapeutic W Sue T Griffin PMCID: PMC2241592 Hypothesis Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis? James M Kelley, Laura B Hughes, and S Louis Bridges, Jr PMCID: PMC2235846 Research Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt Bin Xing, Tao Xin, Randy Lee Hunter, and Guoying Bing PMCID: PMC2254610 Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease Jian Luo, Peggy Ho, Lawrence Steinman, and Tony Wyss-Coray PMCID: PMC2267451 Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease James B Koprich, Casper Reske-Nielsen, Prabhakar Mithal, and Ole Isacson PMCID: PMC2292163 Plaque complement activation and cognitive loss in Alzheimer's disease David A Loeffler, Dianne M Camp, and David A Bennett PMCID: PMC2292690 Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment Liya Qin, Jun He, Richard N Hanes, Olivera Pluzarev, Jau-Shyong Hong, and Fulton T Crews PMCID: PMC2373291 Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2 Kiyomi Takahashi, Nobuaki Funata, Fusahiro Ikuta, and Shigehiro Sato PMCID: PMC2330034 Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease Xuesong Chen, Jeremy W Gawryluk, John F Wagener, Othman Ghribi, and Jonathan D Geiger PMCID: PMC2330033 Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid Kathryn E Nichol, Wayne W Poon, Anna I Parachikova, David H Cribbs, Charles G Glabe, and Carl W Cotman PMCID: PMC2329612 The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection Thi A Tran, Melissa K McCoy, Michael B Sporn, and Malú G Tansey PMCID: PMC2396606 Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia Christopher J Henry, Yan Huang, Angela Wynne, Mark Hanke, Justin Himler, Michael T Bailey, John F Sheridan, and Jonathan P Godbout PMCID: PMC2412862 Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2 Saba Aid, Robert Langenbach, and Francesca Bosetti PMCID: PMC2409311 VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult Jae K Ryu and James G McLarnon PMCID: PMC2430697 Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease Alexander Harkavyi, Amjad Abuirmeileh, Rebecca Lever, Ann E Kingsbury, Christopher S Biggs, and Peter S Whitton PMCID: PMC2426681 Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis Andre M Mueller, Xiomara Pedré, Thomas Stempfl, Ingo Kleiter, Sebastien Couillard-Despres, Ludwig Aigner, Gerhard Giegerich, and Andreas Steinbrecher PMCID: PMC2438345 Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity Dan Zhang, Xiaoming Hu, Sung-Jen Wei, Jie Liu, Huiming Gao, Li Qian, Belinda Wilson, Gengtao Liu, and Jau-Shyong Hong PMCID: PMC2413210 Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease Jing-Ji Jin, Hong-Duck Kim, J Adam Maxwell, Ling Li, and Ken-ichiro Fukuchi PMCID: PMC2430555 GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice Longxuan Li, Jun Liu, and William Z Suo PMCID: PMC2442054 Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury Hal X Nguyen, Manuel D Galvan, and Aileen J Anderson PMCID: PMC2443364 Evidence of platelet activation in multiple sclerosis William A Sheremata, Wenche Jy, Lawrence L Horstman, Yeon S Ahn, J Steven Alexander, and Alireza Minagar PMCID: PMC2474601 Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury Eric Lloyd, Kathleen Somera-Molina, Linda J Van Eldik, D Martin Watterson, and Mark S Wainwright PMCID: PMC2483713 Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation Katie Moisse, Ian Welch, Tracy Hill, Kathryn Volkening, and Michael J Strong PMCID: PMC2474603 Histoplasma capsulatum yeast phase-specific protein Yps3p induces Toll-like receptor 2 signaling Rajagopal N Aravalli, Shuxian Hu, Jon P Woods, and James R Lokensgard PMCID: PMC2474602 Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone Stefan M Gold, Sara Chalifoux, Barbara S Giesser, and Rhonda R Voskuhl PMCID: PMC2518142 P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis Anthony J Sharp, Paul E Polak, Vittoria Simonini, Shao X Lin, Jill C Richardson, Ernesto R Bongarzone, and Douglas L Feinstein PMCID: PMC2518548 Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat Christopher C Leonardo, Autumn K Eakin, Joanne M Ajmo, Lisa A Collier, Keith R Pennypacker, Alex Y Strongin, and Paul E Gottschall PMCID: PMC2527306 MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult Wendy L Thompson, William J Karpus, and Linda J Van Eldik PMCID: PMC2527558 Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease Anastazija Gnjec, Katarzyna J D'Costa, Simon M Laws, Ross Hedley, Kelvin Balakrishnan, Kevin Taddei, Georgia Martins, Athena Paton, Giuseppe Verdile, Samuel E Gandy, G Anthony Broe, William S Brooks, Hayley Bennett, Olivier Piguet, Patricia Price, Judith Miklossy, Joachim Hallmayer, Patrick L McGeer, and Ralph N Martins PMCID: PMC2538517 Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation Jae Woong Lee, Yong Kyung Lee, Dong Yeon Yuk, Dong Young Choi, Sang Bae Ban, Ki Wan Oh, and Jin Tae Hong PMCID: PMC2556656 Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism Alexander Semmler, Sven Hermann, Florian Mormann, Marc Weberpals, Stephan A Paxian, Thorsten Okulla, Michael Schäfers, Markus P Kummer, Thomas Klockgether, and Michael T Heneka PMCID: PMC2553764 Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats Stefan A Mann, Beatrix Versmold, Romy Marx, Sabine Stahlhofen, Irmgard D Dietzel, Rolf Heumann, and Richard Berger PMCID: PMC2562366 Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis Judith Miklossy, Sandor Kasas, Anne D Zurn, Sherman McCall, Sheng Yu, and Patrick L McGeer PMCID: PMC2564911 Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression Kavon Rezai-Zadeh, Jared Ehrhart, Yun Bai, Paul R Sanberg, Paula Bickford, Jun Tan, and R Douglas Shytle PMCID: PMC2569027 Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice Irina Petrushina, Anahit Ghochikyan, Mikayel Mkrtichyan, Grigor Mamikonyan, Nina Movsesyan, Rodmehr Ajdari, Vitaly Vasilevko, Adrine Karapetyan, Andrew Lees, Michael G Agadjanyan, and David H Cribbs PMCID: PMC2567310 Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway Teresa F Pais, Catarina Figueiredo, Rui Peixoto, Maria H Braz, and Sukalyan Chatterjee PMCID: PMC2572162 Hematopoietic cell activation in the subventricular zone after Theiler's virus infection Gwendolyn E Goings, Adriana Greisman, Rachel E James, Leanne KF Abram, Wendy Smith Begolka, Stephen D Miller, and Francis G Szele PMCID: PMC2577640 Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice Bettina H Clausen, Kate L Lambertsen, Alicia A Babcock, Thomas H Holm, Frederik Dagnaes-Hansen, and Bente Finsen PMCID: PMC2585073 Focal cerebral ischemia in the TNFalpha-transgenic rat L Creed Pettigrew, Mark S Kindy, Stephen Scheff, Joe E Springer, Richard J Kryscio, Yizhao Li, and David S Grass PMCID: PMC2583993 Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection Gretchen Hermes, James W Ajioka, Krystyna A Kelly, Ernest Mui, Fiona Roberts, Kristen Kasza, Thomas Mayr, Michael J Kirisits, Robert Wollmann, David JP Ferguson, Craig W Roberts, Jong-Hee Hwang, Toria Trendler, Richard P Kennan, Yasuhiro Suzuki, Catherine Reardon, William F Hickey, Lieping Chen, and Rima McLeod PMCID: PMC2588578 Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice Adriana C Dos Santos, Ester Roffê, Rosa ME Arantes, Luiz Juliano, Jorge L Pesquero, João B Pesquero, Michael Bader, Mauro M Teixeira, and Juliana Carvalho-Tavares PMCID: PMC2596102 Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection Mikhail V Ovanesov, Yavuz Ayhan, Candie Wolbert, Krisztina Moldovan, Christian Sauder, and Mikhail V Pletnikov PMCID: PMC2588577 Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study Harumi Jyonouchi, Lee Geng, Agnes Cushing-Ruby, and Huma Quraishi PMCID: PMC2625336 Reviews The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective Solomon S Shaftel, W Sue T Griffin, and M Kerry O'Banion PMCID: PMC2335091 Neuromyelitis optica pathogenesis and aquaporin 4 David J Graber, Michael Levy, Douglas Kerr, and William F Wade PMCID: PMC2427020 Interactions between APP secretases and inflammatory mediators Magdalena Sastre, Jochen Walter, and Steve M Gentleman PMCID: PMC2442055 TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease Melissa K McCoy and Malú G Tansey PMCID: PMC2577641 Inflammaging as a prodrome to Alzheimer's disease Brian Giunta, Francisco Fernandez, William V Nikolic, Demian Obregon, Elona Rrapo, Terrence Town, and Jun Tan PMCID: PMC2615427 Short Reports Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo Piali Mukherjee, Sunil Thomas, and Giulio Maria Pasinetti PMCID: PMC2246107 Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus Mikhail V Ovanesov, Krisztina Moldovan, Kimberly Smith, Michael W Vogel, and Mikhail V Pletnikov PMCID: PMC2397384 Acute hemorrhagic demyelination in a murine model of multiple sclerosis Istvan Pirko, Georgette L Suidan, Moses Rodriguez, and Aaron J Johnson PMCID: PMC2474604 |
