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BMC Structural Biology

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Danielle Talbot


Welcome to BMC Structural Biology published by BioMed Central
BMC Structural Biology is an open access journal publishing original peer-reviewed research articles in investigations into the structure and function of biological macromolecules. BMC Structural Biology (ISSN 1472-6807) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.



BMC Featured articles

BMC Structural Biology 2008, 8:43
BMC Structural Biology 2008, 8:43
A new method which uses information theory to map information exchange on protein domain structures shows how binding may trigger conformational changes and specifically how signal transduction in Fyn tyrosine kinase resembles noisy channel communication.
BMC Structural Biology 2008, 8:42
BMC Structural Biology 2008, 8:42
The first crystal structure of a eukaryotic guanylate cyclase - from the green alga, Chlamydomonas reinhardtii - confirms the expected close structural similarity with adenylate cyclases and provides clues as to how activation of the enzyme could occur.
Dasgupta and Chakrabarti BMC Struct Biol 2008
BMC Structural Biology 2008, 8:39
Systematically classifying pi-turns in protein structures by measuring the presence of hydrogen bonds, the distance between terminal Calpha atoms and backbone torsion angles indicates that at least 20% occur independent of the Schellman motif.


BMC  Latest articles published in BMC Structural Biology        [more info]


Research article
Mesothelin, Stereocilin, and Otoancorin are predicted to have superhelical structures with ARM-type repeats
Bangalore K Sathyanarayana, Yoonsoo Hahn, Manish S Patankar, Ira Pastan, Byungkook Lee
BMC Structural Biology 2009, 9:1 (7January2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families
Ratna R Thangudu, Malini Manoharan, Srinivasan N, Frederic Cadet, Sowdhamini R, Bernard Offmann
BMC Structural Biology 2008, 8:55 (26December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Knottin cyclization: Impact on Structure and Dynamics
Annie Heitz, Olga Avrutina, Dung Le-Nguyen, Ulf Diederichsen, Jean-Francois Hernandez, Jerome Gracy, Harald Kolmar, Laurent Chiche
BMC Structural Biology 2008, 8:54 (12December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Residue contact-count potentials are as effective as residue-residue contact-type potentials for ranking protein decoys
Dan M Bolser, Ioannis Filippis, Henning Stehr, Jose Duarte, Michael Lappe
BMC Structural Biology 2008, 8:53 (8December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
SELECTpro: effective protein model selection using a structure-based energy function resistant to BLUNDERs
Arlo Randall, Pierre Baldi
BMC Structural Biology 2008, 8:52 (3December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Software
PDBalert: automatic, recurrent remote homology tracking and protein structure prediction
Vatsal Agarwal, Michael Remmert, Andreas Biegert, Johannes Sding
BMC Structural Biology 2008, 8:51 (25November2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Ligand-induced conformational changes in a thermophilic ribose-binding protein
Matthew J Cuneo, Lorena S Beese, Homme W Hellinga
BMC Structural Biology 2008, 8:50 (19November2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Software
HOLLOW: Generating Accurate Representations of Channel and Interior Surfaces in Molecular Structures
Bosco K Ho, Franz Gruswitz
BMC Structural Biology 2008, 8:49 (14November2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site
Katarzyna H Kaminska, Mikihiko Kawai, Michal Boniecki, Ichizo Kobayashi, Janusz M Bujnicki
BMC Structural Biology 2008, 8:48 (14November2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Database
LRRML: a conformational database and an XML description of leucine-rich repeats (LRRs)
Tiandi Wei, Jing Gong, Ferdinand Jamitzky, Wolfgang M Heckl, Robert W Stark, Shaila C Roessle
BMC Structural Biology 2008, 8:47 (5November2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
CD24 regulated gene expression and distribution of tight junction proteins is associated with altered barrier function in oral epithelial monolayers
Ping Ye, Mangala A Nadkarni, Mary Simonian, Neil Hunter
BMC Cell Biology 2009, 10:2 (13January2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Chromatid recommensuration after segmental duplication
Mark N Jabbour
Theoretical Biology and Medical Modelling 2009, 6:1 (7January2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Automated alphabet reduction for protein datasets
Jaume Bacardit, Michael Stout, Jonathan D Hirst, Alfonso Valencia, Robert E Smith, Natalio Krasnogor
BMC Bioinformatics 2009, 10:6 (6January2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Debate
Is a purpose of REM sleep atonia to help regenerate intervertebral disc volumetric loss?
Jerome C J Fryer
Journal of Circadian Rhythms 2009, 7:1 (5January2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Case Report
A forensic aspect of age characteristics of dentine using transversal microradiography: a case report
Leonidas Vasiliadis, Christos Stavrianos, Panagiotis Kafas
Cases Journal 2009, 2:4 (2January2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Case Report
Dynamic splinting for knee flexion contracture following total knee arthroplasty: a case report
Eric Finger, F Buck Willis
Cases Journal 2008, 1:421 (29December2008)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research article
Transcriptional Regulation of BRD7 Expression By Sp1 And c-Myc
Huaying Liu, Ming Zhou, Xiaomin Luo, Liming Zhang, Zhaoxia Niu, Cong Peng, Jian Ma, Shuping Peng, Houde Zhou, Bo Xiang, Xiayu Li, Shufang Li, Jiajin He, Xiaoling Li, Guiyuan Li
BMC Molecular Biology 2008, 9:111 (27December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
An evolutionary and structural characterization of mammalian protein complex organization
Philip Wong, Sonja Althammer, Andrea Hildebrand, Andreas Kirschner, Philipp Pagel, Bernd Geissler, Pawel Smialowski, Florian Bloechl, Matthias Oesterheld, Thorsten Schmidt, Normann Strack, Fabian Theis, Andreas Ruepp, Dmitrij Frishman
BMC Genomics 2008, 9:629 (23December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Essential operating principles for tumor spheroid growth
Jesse A. Engelberg, Glen E. P. Ropella, C. Anthony Hunt
BMC Systems Biology 2008, 2:110 (23December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The meaning of alignment: lessons from structural diversity
Walter Pirovano, K. Anton Feenstra, Jaap Heringa
BMC Bioinformatics 2008, 9:556 (23December2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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