BMC Medical Research Methodology
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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Iratxe Puebla
Welcome to BMC Medical Research Methodology published by BioMed Central
BMC Medical Research Methodology is an open access journal publishing original peer-reviewed research articles in methodological approaches to healthcare research. Articles on the methodology of epidemiological research, clinical trials and meta-analysis/systematic review are particularly encouraged, as are empirical studies of the associations between choice of methodology and study outcomes. BMC Medical Research Methodology does not aim to publish articles describing scientific methods or techniques: these should be directed to the BMC journal covering the relevant biomedical subject area.
BMC Medical Research Methodology (ISSN 1471-2288) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Medical Research Methodology 2008, 8 :79
While the heterogeneity statistic I^2 increases with the studies' sample size, tau^2 measures the clinical relevance of any heterogeneity, and is a more appropriate tool for deciding whether to pool treatment estimates in a meta-analysis.
BMC Medical Research Methodology 2008, 8 :65
A novel randomization tool runs allocation-concealed block randomization for cluster randomized trials and minimizes imbalances between treatment groups across multiple baseline covariates.
BMC Medical Research Methodology 2008, 8 :59
Quantile regression and generalized additive models for location, scale and shape are more appropriate regression approaches than generalized linear models to predict childhood body mass index from obesity risk factor analysis.
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Research article
Assessment of regression-based methods to adjust for publication bias through a comprehensive simulation study Santiago G Moreno, Alex J Sutton, A E Ades, Tom D Stanley, Keith R Abrams, Jaime L Peters, Nicola J Cooper BMC Medical Research Methodology 2009, 9 :2 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Spontaneous improvement in randomised clinical trials: meta-analysis of three-armed trials comparing no treatment, placebo and active intervention Lasse Theis Krogsboll, Asbjorn Hrobjartsson, Peter C Gotzsche BMC Medical Research Methodology 2009, 9 :1 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Estimating adjusted prevalence ratio in clustered cross-sectional epidemiological data Carlos Ant BMC Medical Research Methodology 2008, 8 :80 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Undue reliance on I^2 in assessing heterogeneity may mislead Gerta Rucker, Guido Schwarzer, James R Carpenter, Martin Schumacher BMC Medical Research Methodology 2008, 8 :79 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
A comparison of two methods for estimating odds ratios: Results from the National Health Survey Enayatollah Bakhshi, Mohammad R Eshraghian, Kazem Mohammad, Behjat Seifi BMC Medical Research Methodology 2008, 8 :78 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Improving quality indicator report cards through Bayesian modeling Byron J Gajewski, Jonathan D Mahnken, Nancy Dunton BMC Medical Research Methodology 2008, 8 :77 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Estimating preferences for a dermatology consultation using Best-Worst Scaling: Comparison of various methods of analysis Terry N Flynn, Jordan J Louviere, Tim J Peters, Joanna Coast BMC Medical Research Methodology 2008, 8 :76 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Statistical methods to correct for verification bias in diagnostic studies are inadequate when there are few false negatives: a simulation study Angel M Cronin, Andrew J Vickers BMC Medical Research Methodology 2008, 8 :75 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Accuracy of death certification and hospital record linkage for identification of incident stroke Shubhada Sinha, Phyo K Myint, Robert N Luben, Kay-Tee Khaw BMC Medical Research Methodology 2008, 8 :74 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Debate
Using reflexivity to enhance in-depth interviewing skills for the clinician researcher. Ruth McNair, Angela Taft, Kelsey Hegarty BMC Medical Research Methodology 2008, 8 :73 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics Andres F Zuluaga, Maria Agudelo, Carlos A Rodriguez, Omar Vesga BMC Clinical Pharmacology 2009, 9 :1 (16 [Abstract ] [Provisional PDF ]
Study protocol
Efficacy of intra-articular hyaluronan (Synvisc) for the treatment of osteoarthritis affecting the first metatarsophalangeal joint of the foot (hallux limitus): study protocol for a randomised placebo controlled trial Shannon E Munteanu, Hylton B Menz, Gerard V Zammit, Karl B Landorf, Christopher J Handley, Ayman ElZarka, Jason DeLuca Journal of Foot and Ankle Research 2009, 2 :2 (16 [Abstract ] [Provisional PDF ]
Research article
Evaluation of trauma care using TRISS method: the role of adjusted misclassification rate and adjusted w-statistic
Sadik S Llullaku, Nexhmi SH Hyseni, Cen I Bytyqi, Sylejman K Rexhepi World Journal of Emergency Surgery 2009, 4 :2 (15 [Abstract ] [Provisional PDF ]
Review
Are animal models predictive for humans? Niall Shanks, Ray Greek, Jean Greek Philosophy, Ethics, and Humanities in Medicine 2009, 4 :2 (15 [Abstract ] [Provisional PDF ]
Research
Impact of GnRH ovarian stimulation protocols on intracytoplasmic sperm injection outcomes Fatima Pinto, Cristiano Oliveira, Margarida F Cardoso, Jose Teixeira-da-Silva, Joaquina Silva, Mario Sousa, Alberto Barros Reproductive Biology and Endocrinology 2009, 7 :5 (15 [Abstract ] [Provisional PDF ]
Methodology
High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia Gero Hutter, Anne Letsch, Daniel Nowak, Julia Poland, Pranav Sinha, Eckhard Thiel, Wolf K Hofmann Journal of Translational Medicine 2009, 7 :7 (15 [Abstract ] [Provisional PDF ]
Research article
Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis Milo A Puhan, Lucas M Bachmann, Jos Kleijnen, Gerben ter Riet, Alphons G Kessels BMC Medicine 2009, 7 :2 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Evidence-based effect size estimation: An illustration using the case of acupuncture for cancer-related fatigue Michael F. Johnston, Ron D. Hays, Ka-Kit Hui BMC Complementary and Alternative Medicine 2009, 9 :1 (13 [Abstract ] [Provisional PDF ]
Research
Perioperative immune responses in cancer patients undergoing digestive surgeries Masashi Ishikawa, Masanori Nishioka, Norikazu Hanaki, Takayuki Miyauchi, Yutaka Kashiwagi, Hiromi Ioki, Hiroaki Kagawa, Yoichi Nakamura World Journal of Surgical Oncology 2009, 7 :7 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Histopathological and biochemical effects of green tea and/or licorice aqueous extracts on thyroid functions in male albino rats intoxicated with dimethylnitrosamine
Abd El Mgeed A., Bstawi M., Mohamed U., Abdel Gabbar M. Nutrition & Metabolism 2009, 6 :2 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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