Drug Registration > PDF Forms > DEA Form 224 Instructions

DEA Form 224  
New Application for Registration Instructions

• Section 1 - Application Identification

• Section 2 - Business Activity

• Section 3 - Drug Schedules

  • Schedule II

  • Schedule III

  • Schedule IV

  • Schedule V

• Section 4 - State License(s)

• Section 5 - Liability

• Section 6 - Certification of Exemption

• Section 7 - Method of Payment

• Section 8 - Applicant's Signature

• Contact Information

• Notice of Registrants Making Payment by Check

SECTION 1. APPLICANT IDENTIFICATION

Information must be typed or printed in the blocks provided to help reduce data entry errors.  A physical address is required; after the street address a post office box may be included. Fee exempt applications must list the name and address of the fee exempt institution.

Applicant must enter a valid social security number (SSN), or a tax identification number (TIN) if applying as a business entity. 
Debt collection information is mandatory pursuant to the Debt Collection Improvement Act of 1996

The email address, point of contact, national provider id, date of birth, year graduated, and professional school are new data items that are in the process of OMB approval and will soon be mandatory. They are requested in order to facilitate communication or as required by inter-agency data sharing requirements.

Practitioners also enter one degree from this list: DDS, DMD, DO, DPM, DVM, MD or PHD.

Midlevel practitioners also enter one degree from these choices: DOM, HMD, MP, ND, NP, OD, PA, or RPH.

SECTION 2. BUSINESS ACTIVITY

Indicate only one.  Practitioner or mid-level practitioner must enter the degree conferred, and are requested to enter the last professional school of matriculation and the year graduated.

ADS must provide current DEA registration number of parent retail pharmacy or hospital, and attach a notarized affidavit (21 CFR Part 1301.17). Affidavit must include

1. Name of parent retail pharmacy and complete address

2. Name of Long-term Care (LTC) facility and complete address

3. Permit or license number(s) and date issued of State certification to operate ADS at named LTC facility

4. Required Statement: 
   This affidavit is submitted to obtain a DEA registration number. If any material information is false, the Administrator may commence proceedings to deny the application under section 304 of the Act (21 U.S.C. 8224(a)). Any false or fraudulent material information contained in this affidavit may subject the person signing this affidavit, and the named corporation/partnership/business to prosecution under section 403 of the Act (21 U.S.C 843). 

5. Name of corporation operating the retail pharmacy

6. Name and title of corporate officer signing affidavit

7. Signature of authorized officer

SECTION 3. DRUG SCHEDULES

Applicants should check all drug schedules to be handled. However, applicants must still comply with state requirements; federal registration does not overrule state restrictions. Check the order form box only if you intend to purchase or to transfer schedule II controlled substances. Order forms will be mailed to the registered address following issuance of a Certificate of Registration. The following list of drug codes are examples of controlled substances for schedules 2, 3, 4, and 5. Refer to the CFR for a complete list of basic classes.

DRUG SCHEDULES

Listed below are examples of the schedules with assigned drug code numbers. If you are in need of additional information, see 21 CFR 1308 or contact the DEA office serving your area.

Schedule II

NARCOTIC BASIC CLASSES	CODE
Alphaprodine (Nisentil)	9010
Anileridine (Leritine)	9020
Cocaine (Methyl Benzoylecgonine)	9041
Codeine (Morphine methyl ester)	9050
Dextropropoxyphene (bulk)	9273
Diphenoxylate	9170
Diprenorphine (M50-50)	9058
Ethylmorphine (Dionin)	9190
Etorphine Hydrochloride (M-99)	9059
Glutethimide (Doriden, Dorimide)	2550
Hydrocodone (Dihydrocodeinone)	9193
Hydromorphone (Dialudid)	9150
Levo-alphacetylmethadol (LAAM)	9648
Levorphanol (Levo-Dromoran)	9220
Meperidine (Demerol, Mepergan)	9230
Methadone (Dolophine, Methadose)	9250
Morphine (MS Contin, Roxanol)	9300
Opium, powdered	9639
Opium, raw	9600
Oxycodone (Oxycontin, Percocet)	9143
Oxymorphone (Numorphan)	9652
Opium Poppy / Poppy Straw	9671
Poppy Straw Concentrate	9670
Thebaine	9333
NON-NARCOTIC BASIC CLASSES	CODE
Amobarbital (Amytal, Tuinal)	2125
Amphetamine (Dexedrine, Adderall)	1100
Methamphetamine (Desoxyn)	1105
Methylphenidate (Concerta, Ritalin)	1724
Pentobarbital (Nemutal)	2270
Phencyclidine (PCP)	7471
Phenmetrazine (Preludin)	1631
Phenylacetone	8501
Secobarbital (Seconal)	2315

Schedule III

NARCOTIC BASIC CLASSES	CODE
Buprenorphine (Buprenex, Temgesic, Subutex	9064
Codeine combo product up to 90 mg/du (Empirin)	9319
Dihydrocodeine combo prod 90 mg/du (Compal)	9807
Ethylmorphine combo product 15 mg/du	9808
Hydrocodone combo product (Lorcet, Vicodin)	9806
Morphine combo product  50 mg/100ml or gm	9810
Opium combo product 25 mg/du (Paregoric)	9809
NON-NARCOTIC BASIC CLASSES	CODE
Anabolic Steroids	4000
Benzphetamine (Didrex, Inapetyl)	1228
Butalbital (Fiorinal, Butalbital w/aspirin)	2100/2165
Dronabinol in sesame oil w/soft gelatin capsule	7369
GHB Drug Product (gamma-Hydroxybutyric acid)	2010
Ketamine (Ketaset)	7285
Methyprylon (Noludar)	2575
Pentobarbital suppository du & noncontrolled active ingred. (FP-3, WANS)	2271
Phendimetrazine (Plegine, Bontril, Statobex	1615
Secobarbital suppository du & noncontrolled active ingredients	2316
Thiopental (Pentothal)	2100/2329
Vinbarbital (Delvinal	2100/2335

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Schedule IV

BASIC CLASSES	CODE
Alprzolam (Xanax)	2882
Barbital (Veronal, Plexonal, Barbitone)	2145
Chloral Hydrate (Noctec)	2465
Chlordiazepoxide (Librium, Libritabs)	2744
Clorazepate (Tranxene)	2768
Dextropropoxyphene du (Darvon)	9278
Diazepam (Valium, Diastat)	2765
Diethylpropion (Tenuate, Tepanil)	1610
Difenoxin 1mg/25ug atropine SO4/du (Motofen)	9167
Fenfluramine (Pondimin, Dexfenfluramine)	1670
Flurazepam (Dalmane)	2767
Halazepam (Paxipam)	2762
Lorazepam (Ativan)	2885
Mazindol (Sanorex, Mazanor)	1605
Mebutamate (Capla)	2800
Meprobamate (Miltown, Equanil)	2820
Methohexital (Brevital	2264
Methylphenobarbital (Mebaral)	2250
Midazolam (Versed)	2884
Oxazepam (Serax, Serenid-D))	2835
Paraldehyde (Paral)	2585
Pemoline (Cylert)	1530
Pentazocine (Talwin, Talacen)	9709
Phenobarbital (Luminal, Donnatal)	2285
Phentermine (Ionamin, Fastin, Zantryl)	1640
Prazepam (Centrax)	2764
Quazepam (Doral)	2881
Temazepam (Restoril)	2925
Triazolam (Halcion)	2887
Zolpidem (Ambien, Ivadal, Stilnox)	2783

Schedule V

BASIC CLASSES	CODE
Codeine Cough Preparation (Cosanyl, Pediacof)	9100
Difenoxin Preparation (Motofen)	9167
Dihydrocodeine Preparation (Cophene-S)	9120
Diphenoxylate Preparation (Lomotil, Logen)	9170
Ethylmorphine Preparation	9190
Opium Preparation (Kapectolin PG)	9809

 

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SECTION 4. STATE LICENSE(S)

Federal registration by DEA is based upon the applicant 's compliance with applicable state and local laws. Applicants should contact the local state licensing authority prior to completing this application. If your state requires a separate controlled substance number, provide that number on this application. 

SECTION 5. LIABILITY

Applicants must answer all four questions for the application to be accepted for processing. If you answered "Yes" to any question, provide an explanation in the space provided. If you answer "Yes" to several of the questions, then you must provide a separate explanation describing the location, nature, and result of incident for each "Yes" answer. If additional space is required, you may attach a separate sheet of paper.

SECTION 6. EXEMPTION APPLICATION FEE

Exemption from payment of application fee is limited to federal, state or local government official or institution. The applicant's superior or agency officer must certify exempt status. The signature, authority title, and telephone number of the certifying official (other than the applicant) must be provided. The address of the fee exempt institution must appear in Section 1.

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SECTION 7. METHOD OF PAYMENT

Indicate the desired method of payment. Make checks payable to "Drug Enforcement Administration". Third-party checks or checks drawn on foreign banks will not be accepted. FEES ARE NON-REFUNDABLE.

SECTION 8. APPLICANT'S SIGNATURE

Applicant MUST sign in this section or application will be returned. Card holder signature in section 7 does not fulfill this requirement.

1. INTERNET www.deadiversion.usdoj.gov
2. TELEPHONE Headquarters Call Center (800) 882-9539
3. WRITTEN INQUIRIES – P.O. Box 28083 Washington, D.C. 20038-8083
4. DEA OFFICES (800, 877, and 888 are toll-free numbers)

Authorization to Convert Your Check: 

If you send us a check to make your payment, your check will be converted into an electronic fund transfer. "Electronic fund transfer" is the term used to refer to the process in which we electronically instruct your financial institution to transfer funds from your account to our account, rather than processing your check. By sending your completed, signed check to us, you authorize us to copy your check and to use the account information from your check to make an electronic fund transfer from your account for the same amount as the check. If the electronic fund transfer cannot be processed for technical reasons, you authorize us to process the copy of your check.

Insufficient Funds: 

The electronic funds transfer from your account will usually occur with 24 hours, which is faster than a check is normally processed. Therefore, make sure there are sufficient funds available in your checking account when you send us your check. If the electronic funds transfer cannot be completed because of insufficient funds, we may try to make the transfer up to two times.

Transaction Information: 

The electronic fund transfer from your account will be on the account statement you receive from your financial institution. However, the transfer may be in a different place on your statement than the place where your checks normally appear. For example, it may appear under "other withdrawals" or "other transactions." You will not receive your original check back from your financial institution. For security reasons, we will destroy your original check, but we will keep a copy of the check for record-keeping purposes.

Your Rights: 

You should contact your financial institution immediately if you believe that the electronic fund transfer reported on your account statement was not properly authorized or is otherwise incorrect. Consumers have protections under Federal law called the Electronic Fund Transfer Act for an unauthorized or incorrect electronic fund transfer.

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