Advance online publication
The latest research papers brought to you ahead of print publication by Nature AOP. Advance online publication papers are listed below and grouped by their publication date online.
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03 December 2008
Article
Spliceosomal cleavage generates the 3' end of telomerase RNA
Jessica A. Box, Jeremy T. Bunch, Wen Tang & Peter Baumann
doi:10.1038/nature07584
Abstract | Full Text | PDF (598K) | Supplementary information
Letters
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
Cristina Lo Celso, Heather E. Fleming, Juwell W. Wu, Cher X. Zhao, Sam Miake-Lye, Joji Fujisaki, Daniel Côté, David W. Rowe, Charles P. Lin & David T. Scadden
doi:10.1038/nature07434
First paragraph | Full Text | PDF (1,458K) | Supplementary information
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
Patrick Narbonne & Richard Roy
doi:10.1038/nature07536
First paragraph | Full Text | PDF (697K) | Supplementary information
A simple model of bipartite cooperation for ecological and organizational networks
Serguei Saavedra, Felix Reed-Tsochas & Brian Uzzi
doi:10.1038/nature07532
First paragraph | Full Text | PDF (363K) | Supplementary information
Detection of functional haematopoietic stem cell niche using real-time imaging
Yucai Xie, Tong Yin, Winfried Wiegraebe, Xi C. He, Diana Miller, Danny Stark, Katherine Perko, Richard Alexander, Joel Schwartz, Justin C. Grindley, Jungeun Park, Jeff S. Haug, Joshua P. Wunderlich, Hua Li, Simon Zhang, Teri Johnson, Ricardo A. Feldman & Linheng Li
doi:10.1038/nature07639
First paragraph | Full Text | PDF (1,309K) | Supplementary information
30 November 2008
Letters
The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear
Jessica R. Colantonio, Julien Vermot, David Wu, Adam D. Langenbacher, Scott Fraser, Jau-Nian Chen & Kent L. Hill
doi:10.1038/nature07520
First paragraph | Full Text | PDF (1,349K) | Supplementary information
Protein kinase R reveals an evolutionary model for defeating viral mimicry
Nels C. Elde, Stephanie J. Child, Adam P. Geballe & Harmit S. Malik
doi:10.1038/nature07529
First paragraph | Full Text | PDF (637K) | Supplementary information
Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus
Céline M. O'Gorman, Hubert T. Fuller & Paul S. Dyer
doi:10.1038/nature07528
First paragraph | Full Text | PDF (723K) | Supplementary information
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
Thomas Thum, Carina Gross, Jan Fiedler, Thomas Fischer, Stephan Kissler, Markus Bussen, Paolo Galuppo, Steffen Just, Wolfgang Rottbauer, Stefan Frantz, Mirco Castoldi, Jürgen Soutschek, Victor Koteliansky, Andreas Rosenwald, M. Albert Basson, Jonathan D. Licht, John T. R. Pena, Sara H. Rouhanifard, Martina U. Muckenthaler, Thomas Tuschl, Gail R. Martin, Johann Bauersachs & Stefan Engelhardt
doi:10.1038/nature07511
First paragraph | Full Text | PDF (958K) | Supplementary information
A core gut microbiome in obese and lean twins
Peter J. Turnbaugh, Micah Hamady, Tanya Yatsunenko, Brandi L. Cantarel, Alexis Duncan, Ruth E. Ley, Mitchell L. Sogin, William J. Jones, Bruce A. Roe, Jason P. Affourtit, Michael Egholm, Bernard Henrissat, Andrew C. Heath, Rob Knight & Jeffrey I. Gordon
doi:10.1038/nature07540
First paragraph | Full Text | PDF (429K) | Supplementary information
26 November 2008
Letters
Major gradients in putatively nitrifying and non-nitrifying Archaea in the deep North Atlantic
Hélène Agogué, Maaike Brink, Julie Dinasquet & Gerhard J. Herndl
doi:10.1038/nature07535
First paragraph | Full Text | PDF (332K) | Supplementary information
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
Theresa Alenghat, Katherine Meyers, Shannon E. Mullican, Kirstin Leitner, Adetoun Adeniji-Adele, Jacqueline Avila, Maja Buan, Rexford S. Ahima, Klaus H. Kaestner & Mitchell A. Lazar
doi:10.1038/nature07541
First paragraph | Full Text | PDF (489K) | Supplementary information
Parallel adaptations to high temperatures in the Archaean eon
Bastien Boussau, Samuel Blanquart, Anamaria Necsulea, Nicolas Lartillot & Manolo Gouy
doi:10.1038/nature07393
First paragraph | Full Text | PDF (348K) | Supplementary information
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
Masako Kohyama, Wataru Ise, Brian T. Edelson, Peter R. Wilker, Kai Hildner, Carlo Mejia, William A. Frazier, Theresa L. Murphy & Kenneth M. Murphy
doi:10.1038/nature07472
First paragraph | Full Text | PDF (632K) | Supplementary information
Ferritin is used for iron storage in bloom-forming marine pennate diatoms
Adrian Marchetti, Micaela S. Parker, Lauren P. Moccia, Ellen O. Lin, Angele L. Arrieta, Francois Ribalet, Michael E. P. Murphy, Maria T. Maldonado & E. Virginia Armbrust
doi:10.1038/nature07539
First paragraph | Full Text | PDF (476K) | Supplementary information
23 November 2008
Letters
Analysis of combinatorial cis-regulation in synthetic and genomic promoters
Jason Gertz, Eric D. Siggia & Barak A. Cohen
doi:10.1038/nature07521
First paragraph | Full Text | PDF (518K) | Supplementary information
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
Samir M. Hamdan, Joseph J. Loparo, Masateru Takahashi, Charles C. Richardson & Antoine M. van Oijen
doi:10.1038/nature07512
First paragraph | Full Text | PDF (1,346K) | Supplementary information
Pulsed contractions of an actin–myosin network drive apical constriction
Adam C. Martin, Matthias Kaschube & Eric F. Wieschaus
doi:10.1038/nature07522
First paragraph | Full Text | PDF (1,295K) | Supplementary information
Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids
Zhongfu Ni, Eun-Deok Kim, Misook Ha, Erika Lackey, Jianxin Liu, Yirong Zhang, Qixin Sun & Z. Jeffrey Chen
doi:10.1038/nature07523
First paragraph | Full Text | PDF (759K) | Supplementary information
19 November 2008
Article
The replisome uses mRNA as a primer after colliding with RNA polymerase
Richard T. Pomerantz & Mike O'Donnell
doi:10.1038/nature07527
Abstract | Full Text | PDF (1,991K) | Supplementary information
Letters
Successful range-expanding plants experience less above-ground and below-ground enemy impact
Tim Engelkes, Elly Morriën, Koen J. F. Verhoeven, T. Martijn Bezemer, Arjen Biere, Jeffrey A. Harvey, Lauren M. McIntyre, Wil L. M. Tamis & Wim H. van der Putten
doi:10.1038/nature07474
First paragraph | Full Text | PDF (211K) | Supplementary information
Detecting influenza epidemics using search engine query data
Jeremy Ginsberg, Matthew H. Mohebbi, Rajan S. Patel, Lynnette Brammer, Mark S. Smolinski & Larry Brilliant
doi:10.1038/nature07634
First paragraph | Full Text | PDF (242K) | Supplementary information
Emergence of complex cell properties by learning to generalize in natural scenes
Yan Karklin & Michael S. Lewicki
doi:10.1038/nature07481
First paragraph | Full Text | PDF (908K) | Supplementary information
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
Sandra Rebouissou, Mohamed Amessou, Gabrielle Couchy, Karine Poussin, Sandrine Imbeaud, Camilla Pilati, Tina Izard, Charles Balabaud, Paulette Bioulac-Sage & Jessica Zucman-Rossi
doi:10.1038/nature07475
First paragraph | Full Text | PDF (578K) | Supplementary information
16 November 2008
Letters
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
Maria Barna, Aya Pusic, Ornella Zollo, Maria Costa, Nadya Kondrashov, Eduardo Rego, Pulivarthi H. Rao & Davide Ruggero
doi:10.1038/nature07449
First paragraph | Full Text | PDF (594K) | Supplementary information
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
Jiyun V. Kim, Silvia S. Kang, Michael L. Dustin & Dorian B. McGavern
doi:10.1038/nature07591
First paragraph | Full Text | PDF (1,086K) | Supplementary information
Low conservation of gene content in the Drosophila Y chromosome
Leonardo B. Koerich, Xiaoyun Wang, Andrew G. Clark & Antonio Bernardo Carvalho
doi:10.1038/nature07463
First paragraph | Full Text | PDF (302K) | Supplementary information
Structural recognition and functional activation of FcR by innate pentraxins
Jinghua Lu, Lorraine L. Marnell, Kristopher D. Marjon, Carolyn Mold, Terry W. Du Clos & Peter D. Sun
doi:10.1038/nature07468
PDB code
3D view
First paragraph | Full Text | PDF (817K) | Supplementary information
Highly efficient molybdenum-based catalysts for enantioselective alkene metathesis
Steven J. Malcolmson, Simon J. Meek, Elizabeth S. Sattely, Richard R. Schrock & Amir H. Hoveyda
doi:10.1038/nature07594
First paragraph | Full Text | PDF (660K) | Supplementary information
12 November 2008
Letters
Experience leaves a lasting structural trace in cortical circuits
Sonja B. Hofer, Thomas D. Mrsic-Flogel, Tobias Bonhoeffer & Mark Hübener
doi:10.1038/nature07487
First paragraph | Full Text | PDF (739K) | Supplementary information
Neural processing of auditory feedback during vocal practice in a songbird
Georg B. Keller & Richard H. R. Hahnloser
doi:10.1038/nature07467
First paragraph | Full Text | PDF (789K) | Supplementary information
Memory CD8 T-cell compartment grows in size with immunological experience
Vaiva Vezys, Andrew Yates, Kerry A. Casey, Gibson Lanier, Rafi Ahmed, Rustom Antia & David Masopust
doi:10.1038/nature07486
First paragraph | Full Text | PDF (993K) | Supplementary information
09 November 2008
Letters
A role for VEGF as a negative regulator of pericyte function and vessel maturation
Joshua I. Greenberg, David J. Shields, Samuel G. Barillas, Lisette M. Acevedo, Eric Murphy, Jianhua Huang, Lea Scheppke, Christian Stockmann, Randall S. Johnson, Niren Angle & David A. Cheresh
doi:10.1038/nature07424
First paragraph | Full Text | PDF (791K) | Supplementary information
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
Jinyan Liu, Kara L. O'Brien, Diana M. Lynch, Nathaniel L. Simmons, Annalena La Porte, Ambryice M. Riggs, Peter Abbink, Rory T. Coffey, Lauren E. Grandpre, Michael S. Seaman, Gary Landucci, Donald N. Forthal, David C. Montefiori, Angela Carville, Keith G. Mansfield, Menzo J. Havenga, Maria G. Pau, Jaap Goudsmit & Dan H. Barouch
doi:10.1038/nature07469
First paragraph | Full Text | PDF (352K)
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
Christian Stockmann, Andrew Doedens, Alexander Weidemann, Na Zhang, Norihiko Takeda, Joshua I. Greenberg, David A. Cheresh & Randall S. Johnson
doi:10.1038/nature07445
First paragraph | Full Text | PDF (465K) | Supplementary information
05 November 2008
Letters
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
Nicolas Bocquet, Hugues Nury, Marc Baaden, Chantal Le Poupon, Jean-Pierre Changeux, Marc Delarue & Pierre-Jean Corringer
doi:10.1038/nature07462
PDB code
3D view
First paragraph | Full Text | PDF (1,137K) | Supplementary information
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
Zachary A. Bornholdt & B. V. Venkataram Prasad
doi:10.1038/nature07444
PDB code
3D view
First paragraph | Full Text | PDF (917K) | Supplementary information
WNT11 acts as a directional cue to organize the elongation of early muscle fibres
Jérôme Gros, Olivier Serralbo & Christophe Marcelle
doi:10.1038/nature07564
First paragraph | Full Text | PDF (6,955K) | Supplementary information
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Ricarda J. C. Hilf & Raimund Dutzler
doi:10.1038/nature07461
First paragraph | Full Text | PDF (1,418K) | Supplementary information
G protein Gi functions immediately downstream of Smoothened in Hedgehog signalling
Stacey K. Ogden, Dennis Liang Fei, Neal S. Schilling, Yashi F. Ahmed, John Hwa & David J. Robbins
doi:10.1038/nature07459
First paragraph | Full Text | PDF (651K) | Supplementary information
02 November 2008
Letters
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
Marina Cella, Anja Fuchs, William Vermi, Fabio Facchetti, Karel Otero, Jochen K. M. Lennerz, Jason M. Doherty, Jason C. Mills & Marco Colonna
doi:10.1038/nature07537
First paragraph | Full Text | PDF (678K) | Supplementary information
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
Bernard T. Kelly, Airlie J. McCoy, Kira Späte, Sharon E. Miller, Philip R. Evans, Stefan Höning & David J. Owen
doi:10.1038/nature07422
First paragraph | Full Text | PDF (976K) | Supplementary information
Coordinate control of synaptic-layer specificity and rhodopsins in photoreceptor neurons
Marta Morey, Susan K. Yee, Tory Herman, Aljoscha Nern, Enrique Blanco & S. Lawrence Zipursky
doi:10.1038/nature07419
First paragraph | Full Text | PDF (989K) | Supplementary information
Temporal identity in axonal target layer recognition
Milan Petrovic & Thomas Hummel
doi:10.1038/nature07407
First paragraph | Full Text | PDF (1,109K) | Supplementary information
29 October 2008
Article
Brain metabolism dictates the polarity of astrocyte control over arterioles
Grant R. J. Gordon, Hyun B. Choi, Ravi L. Rungta, Graham C. R. Ellis-Davies & Brian A. MacVicar
doi:10.1038/nature07525
Abstract | Full Text | PDF (1,427K) | Supplementary information
Letter
The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm
Helen Weavers, Silvia Prieto-Sánchez, Ferdinand Grawe, Amparo Garcia-López, Ruben Artero, Michaela Wilsch-Bräuninger, Mar Ruiz-Gómez, Helen Skaer & Barry Denholm
doi:10.1038/nature07526
First paragraph | Full Text | PDF (2,229K) | Supplementary information
26 October 2008
Letter
Generation of cell polarity in plants links endocytosis, auxin distribution and cell fate decisions
Pankaj Dhonukshe, Hirokazu Tanaka, Tatsuaki Goh, Kazuo Ebine, Ari Pekka Mähönen, Kalika Prasad, Ikram Blilou, Niko Geldner, Jian Xu, Tomohiro Uemura, Joanne Chory, Takashi Ueda, Akihiko Nakano, Ben Scheres & Jií Friml
doi:10.1038/nature07409
First paragraph | Full Text | PDF (722K) | Supplementary information
22 October 2008
Letters
Transcription inactivation through local refolding of the RNA polymerase structure
Georgiy A. Belogurov, Marina N. Vassylyeva, Anastasiya Sevostyanova, James R. Appleman, Alan X. Xiang, Ricardo Lira, Stephen E. Webber, Sergiy Klyuyev, Evgeny Nudler, Irina Artsimovitch & Dmitry G. Vassylyev
doi:10.1038/nature07510
PDB code
3D view
First paragraph | Full Text | PDF (681K) | Supplementary information
Generation of a prostate from a single adult stem cell
Kevin G. Leong, Bu-Er Wang, Leisa Johnson & Wei-Qiang Gao
doi:10.1038/nature07427
First paragraph | Full Text | PDF (1,245K) | Supplementary information
Experience with moving visual stimuli drives the early development of cortical direction selectivity
Ye Li, Stephen D. Van Hooser, Mark Mazurek, Leonard E. White & David Fitzpatrick
doi:10.1038/nature07417
First paragraph | Full Text | PDF (955K) | Supplementary information
19 October 2008
Letter
Strong effect of dispersal network structure on ecological dynamics
Matthew D. Holland & Alan Hastings
doi:10.1038/nature07395
First paragraph | Full Text | PDF (379K) | Supplementary information
12 October 2008
Letter
DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes
Andrea L. Bredemeyer, Beth A. Helmink, Cynthia L. Innes, Boris Calderon, Lisa M. McGinnis, Grace K. Mahowald, Eric J. Gapud, Laura M. Walker, Jennifer B. Collins, Brian K. Weaver, Laura Mandik-Nayak, Robert D. Schreiber, Paul M. Allen, Michael J. May, Richard S. Paules, Craig H. Bassing & Barry P. Sleckman
doi:10.1038/nature07392
First paragraph | Full Text | PDF (609K) | Supplementary information
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