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Linus Pauling Institute
Micronutrient Research for Optimum Health

  • Determine the function and role of vitamins and essential minerals (micronutrients) and chemicals from plants (phytochemicals) in promoting optimum health and preventing or treating disease
  • Determine the role of oxidative stress and inflammation in human health and disease, and the protective effects of dietary antioxidant and anti-inflammatory compounds
  • Help people everywhere achieve a healthy and productive life, full of vitality, with minimal suffering, and free of cancer and other debilitating diseases

LPI's Response

Read our response to recently published articles regarding vitamins C and E and heart disease and cancer.


Vitamin C
in the News!

Many of us take vitamin C to ward off a cold, but research is finding that in large doses, the antioxidant might also be a cancer killer. Read more...

See a commentary on the original article published in PNAS.

Major areas of research encompass cardiovascular and metabolic diseases, cancer, aging, immune function, and neurodegenerative diseases. Specific research projects address:

  • Oxidative stress, lipoic acid, and essential metals in atherosclerosis
  • Vitamin E metabolism and biological functions
  • Oxidative and environmental stress in Lou Gehrig's, Parkinson's, and Alzheimer's disease
  • Stress response, lipoic acid, and mitochondrial dysfunction in aging
  • Cancer chemoprotection by phytochemicals in tea and vegetables
  • Transplacental cancer chemoprotection
  • Epigenetic and epigenomic mechanisms of cancer etiology
  • Zinc and antioxidants in prostate cancer and neurodegeneration
  • Novel biological functions of vitamin C
  • Antioxidants and gene expression in diabetes
  • Dietary fats and carbohydrate and lipid metabolism
  • Vitamin D and zinc in immune function

The Linus Pauling Institute relies heavily on public support to fulfill its mission. We invite you to consider the opportunities for giving to the Institute.