Acrylic acid Quickview (CASRN 79-10-7)

Status of Data for Acrylic acid

File First On-Line: 01/31/1987; Last Significant Revision: 04/01/1994

Category (section)	Status	Last Revised
Oral RfD Assessment	On-line	05/01/1994
Inhalation RfC Assessment	On-line	05/01/1995
Carcinogenicity Assessment	No data

Synonyms

79-10-7 Acroleic acid Acrylic acid Acrylic acid, glacial Ethylenecarboxylic acid

Propene acid Propenoic acid 2-Propenoic acid RCRA Waste Number u008 UN 2218

Chronic Health Hazard Assessments for Noncarcinogenic Effects

Reference Dose for Chronic Oral Exposure (RfD)

Critical Effect	Point of Departure*	UF	MF	RfD
Reduced pup weight	NOAEL : 53 mg/kg-day	100	1	5 x10-1 mg/kg-day

* The Point of Departure listed serves as a basis from which the Oral RfD was derived. See Discussion of Conversion Factors and Assumptions for more details.

• Principal and Supporting Studies (Oral RfD)
  • Rat reproductive study, BASF, 1993
• Confidence in the Oral RfD
  • Study -- High
  • Database -- High
  • RfD -- High

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Reference Concentration for Chronic Inhalation Exposure (RfC)

Critical Effect	Point of Departure*	UF	MF	RfC
Degeneration of the nasal olfactory epithelium	LOAEL (HEC): 0.33 mg/m3	300	1	1x10-3 mg/m3

* The Point of Departure listed serves as a basis from which the Inhalation RfC was derived. See Discussion of Conversion Factors and Assumptions for more details.

• Principal and Supporting Studies (Inhalation RfC)
  • Mouse subchronic inhalation study, Miller et al., 1981a
• Confidence in the Inhalation RfC
  • Study -- Medium
  • Database -- Medium
  • RfC -- Medium

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Carcinogenicity Assessment for Lifetime Exposure

• Weight-of-Evidence Characterization
  • Not Assessed under the IRIS Program.

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Quantitative Estimate of Carcinogenic Risk from Oral Exposure

• Not Assessed under the IRIS Program.

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Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure

• Not Assessed under the IRIS Program.