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Health Effects
EPA Grant Number: R827355C002Subproject: this is subproject number 002 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Airborne PM - Northwest Research Center for Particulate Air Pollution and Health
Center Director: Koenig, Jane Q.
Title: Health Effects
Investigators: Koenig, Jane Q. , Jansen, Karen , Kaufman, Joel D. , Larson, Timothy V. , Liu, Sally , Lumley, Thomas , Sheppard, Lianne , Sullivan, Jeff , Trenga, Carol
Current Investigators: Koenig, Jane Q. , Allen, Ryan , Jansen, Karen , Larson, Timothy V. , Lippmann, Morton , Lumley, Thomas , Mar, Therese , Sheppard, Lianne
Institution: University of Washington
EPA Project Officer: Stacey Katz/Gail Robarge,
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2006)
Project Amount: Refer to main center abstract for funding details.
RFA: Airborne Particulate Matter (PM) Centers (1999)
Research Category: Particulate Matter
Description:
Objective:This research project is a health effects panel study that involves comprehensive health monitoring of one healthy and three susceptible subpopulations in Seattle, Spokane, and other cities. The susceptible individuals proposed for study are adults who are 65 years of age or older and have chronic obstructive pulmonary disease (COPD) or cardiovascular disease or children with asthma. The health endpoints to be measured in adult subjects are peak flow, pulse rate, pulse oximetry, blood pressure, and heart rate variability. The health endpoints to be measured in the children with asthma are pulmonary function and symptoms. Personal exposure measurements necessary for associating the health effects with air pollutants will be collected on study participants in Project 2b. Publications and Presentations:
Publications have been submitted on this subproject: View all 27 publications for this subproject | View all 191 publications for this center
Journal Articles:Journal Articles have been submitted on this subproject: View all 18 journal articles for this subproject | View all 94 journal articles for this center
Supplemental Keywords:ambient particles, fine particles, combustion, health, exposure, biostatistics, susceptibility. , Air, Geographic Area, Scientific Discipline, Waste, Health, RFA, Susceptibility/Sensitive Population/Genetic Susceptibility, Toxicology, indoor air, Risk Assessments, genetic susceptability, Northwest, Health Risk Assessment, Incineration/Combustion, Epidemiology, air toxics, Biochemistry, particulate matter, Environmental Chemistry, State, aerosols, combustion contaminants, exposure assessment, incineration, risk assessment, California (CA), exposure and effects, environmental hazard exposures, ambient air quality, cardiovascular disease, elderly, health effects, indoor air quality, inhalation, mortality, allergens, air quality, ambient air, cardiopulmonary response, atmospheric aerosols, cardiopulmonary responses, combustion, human health risk, particle exposure, toxics, air pollutants, biostatistics, human health effects, particulates, sensitive populations, ambient particle health effects, air pollution, airway disease, atmospheric chemistry, children, age dependent response, exposure, human susceptibility, ambient aerosol, asthma, health risks, human exposure, Human Health Risk Assessment, morbidity, animal model, particle transport
Progress and Final Reports:
1999 Progress Report
2000 Progress Report
2001 Progress Report
2002 Progress Report
2003 Progress Report
2004 Progress Report
Final Report
Main Center Abstract and Reports:
R827355 Airborne PM - Northwest Research Center for Particulate Air Pollution and Health
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary
Mortality
R827355C002 Health Effects
R827355C003 Personal PM Exposure Assessment
R827355C004 Characterization of Fine Particulate Matter
R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
R827355C006 Toxicology Project -- Controlled Exposure Facility
R827355C007 Health Effects Research Core
R827355C008 Exposure Core
R827355C009 Statistics and Data Core
R827355C010 Biomarker Core
R827355C011 Oxidation Stress Makers