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Acceptable Substitutes in Retail Food Refrigeration

Ozone Protection Hotline (800) 296-1996

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is available from the hotline. If your browser is unable to display tables, please call the hotline for a free paper copy.

Unacceptable substitutes

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Acceptable Substitutes for CFCs (class I ODS) in Retail Food Refrigeration

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
HCFC-22   12, 502 R, N
Ikon A   12 R, N
Ikon B   12 R, N
THR-02   12 R, N
HFC-134a   12 R, N
HFC-227ea   12 N
R-401A, R-401B MP-39, MP-66 12 R, N
R-402A, R-402B HP-80, HP-81 502 R, N
R-404A HP-62 502, 12, 500 R, N
R-406A GHG 12, 500 R
R-407A, R-407B Klea 407A, 407B 502 R, N
R-408A (HCFC Blend Epsilon)   502 R
R-409A (HCFC Blend Gamma)   12 R
R-411A, R-411B   12, 500, 502 R, N
R-507 AZ-50 502 R, N
Free Zone (HCFC Blend Delta) Free Zone / RB-276 12 R, N
Freeze 12 Freeze 12 12 R, N
FRIGC FR-12 (HCFC Blend Beta) FRIGC FR-12 12, 500 R, N
GHG-X4 GHG-X4, Autofrost, Chill-it 12, 500 R, N
GHG-X5 GHG-X5 12, 500 R, N
GHG-HP (HCFC Blend Lambda) GHG-HP 12 R, N
G2018C G2018C 12, 500, 502 R, N
Hot Shot Hot Shot, Kar Kool 12, 500 R, N
HCFC-22/HCFC-142b   12 R, N
THR-04 THR-04 502 R, N
FOR12A FOR12A 12 R, N
FOR12B FOR12B 12 R, N
SP34E SP34E 12 R, N
Ammonia Vapor Compression With Secondary Loop   all N
HFC-134a/HBr (92/8) as the primary heat transfer fluid in secondary-loop equipment   12, 502 N
HFE-7100 as a secondary heat transfer fluid in not-in-kind systems   12, 502 N
HFE-7200 as a secondary heat transfer fluid in not-in-kind systems   12, 502 N
Self-chilling cans using CO 2   12, 500, 502 N
RS-24 (2002 formulation)   12 R, N
NU-22 NU-22 502 R, N
R-407C Suva 407C, Klea 407C 502 R, N
R-420A Choice R-420A 12, 500 R, N
R-421B Choice R421B 12, 502 R, N
R-426A RS-24 12 R, N
R-422C ICOR XLT1 502 R, N
R-428A RS-52 502 R, N
Key: R = Retrofit Uses, N = New Uses

A cceptable Substitutes for HCFCs (class II ODS) in Retail Food Refrigeration

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/ New
THR-03     N
ISCEON 59, NU-22, R417A Isceon 59, NU-22   R, N
R-410A, R-410B AZ-20, Suva 9100, Puron   N
R-407C Suva 9000, Klea 66   R, N
R-507, R-507A AZ-50   R, N
Ammonia Vapor Compression With Secondary Loop     N
R-404A HP62   R, N
Self-Chilling cans using CO 2     R, N
RS-44 (2003 formulation)   22 R, N
ISCEON 79 ISCEON 79   R, N
R-421B Choice R421B 22 R, N
R-422D ISCEON MO29 22 R, N
R-424A RS-44 22 R, N
R-426A RS-24 22 R, N
KDD5 KDD5 22 R, N
RS-45 (ASHRAE proposed designation: R-434A) RS-45 22 R, N
R-428A RS-52 22, 22 blends including R-402A, - 402B, -408A, AND -411B R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22 R, N
R-422B XAC1, NU-22B 22 R, N
R-422C XLT1 22, 402A, 402B, 408A R, N
Key: R = Retrofit Uses, N = New Uses

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