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Final Report: VOC Exposure in an Industry Impacted Community
EPA Grant Number: R828678C003Subproject: this is subproject number 003 , established and managed by the Center Director under grant R824834
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Mickey Leland National Urban Air Toxics Research Center (NUATRC)
Center Director: Beskid, Craig
Title: VOC Exposure in an Industry Impacted Community
Investigators: Buckley, Timothy
Institution: Johns Hopkins University
EPA Project Officer: Stacey Katz/Gail Robarge,
Project Period: January 2, 2001 through December 31, 2005 (Extended to December 31, 2008)
RFA: Mickey Leland National Urban Air Toxics Research Center (NUATRC) (1997)
Research Category: Targeted Research , Air Quality and Air Toxics
Description:
Objective:The objective of this research project was to measure VOC concentrations for personal exposure assessment by monitoring individual, indoor, and outdoor environments within a South Baltimore community in proximity to industrial emissions. The study is a response to community concerns over the potential health hazard caused by the intensity and proximity of industrial sources. A sample of forty (40) adults and fifteen (15) children in 40 homes in this community were monitored for indoor, outdoor, and personal exposures to volatile organic compounds (VOCs). The substances measured included benzene, 1,3-butadiene, and carbon tetrachloride. In addition to monitoring individuals and environments in the community, control subjects (15 adult and child pairs) in a reference community were monitored. As a result of these measurements, source apportionment was attempted for these specific chemicals.
The main objectives were to: (1) provide VOC exposure information to a concerned community; (2) apportion indoor and outdoor sources; and (3) evaluate benzene as an exposure biomarker.
The National Urban Air Toxics Research Center (NUATRC) support supplemented a previous U.S. Environmental Protection Agency grant, which monitored 30 residents of the exposed community and 15 residents of the comparison unexposed community with Organic Vapor Monitor VOC badges. Separately, the NUATRC support supplemented a National Institute of Environmental Health Sciences first award to measure biomarkers of benzene exposure of the exposed community residents.
Summary/Accomplishments (Outputs/Outcomes):This project was developed in response to NUATRC Request for Application 98-03; “NUATRC New Investigators Small Grants Program” intended to foster the development of short-term research projects on exposures/health effects of urban air toxics by new investigators.
Sampling for the study and analyses of the VOCs were completed in the fall of 2001. During 2002, the investigators completed the analysis of the air exchange rates measurements and cotinine analysis. Analyses of urine samples for benzene metabolite, trans, trans-muconic acid (ttMA) were completed.
The study results show that the influence of industry on community air quality is undetected for most VOCs, although an industry impact (outdoor and indoor) was suggested for m, p-xylene and ethylbenzene. Indoor source contribution was indicated for most VOCs (11 of 15), and although the sample size was small, parent/child exposures were found to be associated. With dietary sorbic acid restriction, a marginal predictive association was seen for ttMA and benzene exposure.
The final report for the study has been published as NUATRC Research Report 4: Buckley TJ, Payne-Sturges D, et al. (2005) “VOC Exposure in an Industry-Impacted Community.” The report is available on the NUATRC Web Site at http://www.sph.uth.tmc.edu/mleland/ 
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Journal Articles on this Report: 2 Displayed | Download in RIS Format
| Other subproject views: | All 3 publications | 3 publications in selected types | All 2 journal articles |
| Other center views: | All 122 publications | 54 publications in selected types | All 46 journal articles |
| Type | Citation | ||
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Payne-Sturges DC, Schwab M, Buckley TJ. Closing the research loop: a risk-based approach for communicating results of air pollution exposure studies. Environmental Health Perspectives 2004;112(1):28-34. |
R828678C003 (2003) R828678C003 (2004) R828678C003 (Final) |
not available |
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Payne-Sturges DC, Burke TA, Breysse P, Diener-West M, Buckley TJ. Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community. Environmental Health Perspectives 2004;112(5):589-598. |
R828678C003 (2003) R828678C003 (2004) R828678C003 (Final) |
not available |
air pollution, urban, monitoring, exposure, methods, indoor air, volatile organic compounds, VOCs, particulate matter, PM, environmental policy, exposure, health risk assessment, physical processes, risk assessments, susceptibility/sensitive population/genetic susceptibility, air toxics, genetic susceptibility, acute health effects, acute cardiovascular effects, acute exposure, acute lung injury, air contaminant exposure, air quality, airborne urban contaminants, airway disease, aldehydes, assessment of exposure, atmospheric particulate matter, cardiac arrest, cardiopulmonary response, children, children’s environmental health, chronic health effects, copollutants, copollutant exposures, environmental hazard exposures, fine particles, health effects, human exposure, human health risk, human susceptibility, inhaled pollutants, long-term exposure, lung inflammation, particulate exposure, sensitive populations, susceptible subpopulations, toxics,
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HUMAN HEALTH, POLLUTANTS/TOXICS, ENVIRONMENTAL MANAGEMENT, Air, Scientific Discipline, Health, RFA, PHYSICAL ASPECTS, Susceptibility/Sensitive Population/Genetic Susceptibility, Risk Assessment, Biology, Risk Assessments, Health Risk Assessment, Physical Processes, air toxics, Chemicals, particulate matter, Environmental Chemistry, Exposure, Air Pollution, biomarkers, chemical mixtures, exposure assessment, environmental hazard exposures, airborne urban contaminants, acute exposure, Acute health effects, Volatile Organic Compounds (VOCs), air contaminant exposure, co-pollutants, air quality, benzene, cardiopulmonary response, fine particles, industrial air pollution, butadiene, cardiopulmonary responses, human health risk, lung inflammation, toxics, acute cardiovascular effects, air pollutants, chronic health effects, PM 2.5, sensitive populations, acute lung injury, atmospheric chemistry, carbon tetrachloride, inhaled, atmospheric particulate matter, copollutant exposures, susceptible subpopulations, long term exposure, human susceptibility, human exposure, PM, particulate exposure
Relevant Websites:
http://www.sph.uth.tmc.edu/mleland/
Progress and Final Reports:
2001 Progress Report
2002 Progress Report
2003 Progress Report
2004 Progress Report
Original Abstract
Main Center Abstract and Reports:
R824834 Mickey Leland National Urban Air Toxics Research Center (NUATRC)
Subprojects under this Center:
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R824834C001 Air Toxics Exposures Among Teenagers in New York City and Los Angeles - A Columbia-Harvard Study (TEACH)
R824834C002 Cardiopulmonary Response to Particulate Exposure
R824834C003 VOC Exposure in an Industry Impacted Community
R824834C004 A Study of Personal Exposure to Air Toxics Among a Subset of the Residential U.S. Population (VOC Project)
R824834C005 Methods Development Project for a Study of Personal Exposures to Toxic Air Pollutants
R824834C006 Relationship Between Indoor, Outdoor and Personal Air (RIOPA)
R824834C007 Development of the "Leland Legacy" Air Sampling Pump
R824834C008 Source Apportionment of Indoor Polycyclic Aromatic Hydrocarbons (PAHs) in Urban Residences
R824834C009 Development of a Personal Cascade Impactor Sampler (PCIS)
R824834C010 Testing the Metals Hypothesis in Spokane
R828678C001 Air Toxics Exposures Among Teenagers in New York City and Los Angeles—A Columbia-Harvard Study (TEACH)
R828678C002 Cardiopulmonary Effects of Metal-Containing Particulate Exposure
R828678C003 VOC Exposure in an Industry Impacted Community
R828678C004 A Study of Personal Exposure to Air Toxics Among a Subset of the Residential U.S. Population (VOC Project)
R828678C005 Oxygenated Urban Air Toxics and Asthma Variability in Middle School Children: A Panel Study (ATAC–Air Toxics and Asthma in Children)
R828678C006 Relationship between Indoor, Outdoor and Personal Air (RIOPA). Part II: Analyses of Concentrations of Particulate Matter Species
R828678C007 Development of the “Leland Legacy” Air Sampling Pump
R828678C008 Source Apportionment of Indoor PAHs in Urban Residences 98-03B
R828678C009 Development of a Personal Cascade Impactor Sampler (PCIS)
R828678C010 Testing the Metals Hypothesis in Spokane
R828678C011 A Pilot Geospatial Analysis of Exposure to Air Pollutants (with Special Attention to Air Toxics) and Hospital Admissions in Harris County, Texas
R828678C012 Impact of Exposure to Urban Air Toxics on Asthma Utilization for the Pediatric Medicaid Population in Dearborn, Michigan
R828678C013 Field Validation of the Sioutas Sampler and Leland Legacy Pump – Joint Project with EPA’s Environmental Technology Validation Program (ETV)
R828678C014 Performance Evaluation of the 3M Charcoal Vapor Monitor for Monitor Low Ambient Concentrations of VOCs
R828678C015 RIOPA Database Development
R828678C016 Contributions of Outdoor PM Sources to Indoor and Personal Exposures: Analysis of PM Species Concentrations” Focused on the PM Speciation and Apportioning of Sources
R828678C017 The Short and Long-Term Respiratory Effects of Exposure to PAHs from Traffic in a Cohort of Asthmatic Children