Projects

SWINE VIRAL DISEASES PATHOGENESIS AND IMMUNOLOGY Appropriated (D)   Accession Number: 411523

GENE EXPRESSION IN LYMPH NODES OF PRRSV-INFECTED PIGS Reimbursable (R)   Accession Number: 415042

Publications

Effect of porcine reproductive and respiratory syndrome virus infection of porcine alveolar macrophages on Toll-like receptors elicitation of type I interferon responses - (Peer Reviewed Journal)

Miller, L.C., Lager, K.M., Kehrli, Jr., M.E. 2009. Role of Toll-Like Receptors in Activation of Porcine Alveolar Macrophages by Porcine Reproductive and Respiratory Syndrome Virus. Clinical and Vaccine Immunology. 16(3):360-365.

Differential roles of Toll-like receptors in the elicitation of type I interferon responses by alveolar macrophages - (Abstract)

Miller, L.C., Chitko-Mckown, C.G., Lager, K.M., Kehrli, Jr., M.E. 2008. Differential Roles of Toll-Like Receptors in the Elicitation of Type I Interferon Responses by Alveolar Macrophages [abstract]. International PRRS Symposium. p. 58.

Effects of PRRSV infection on TLR-dependent induction of NOS - (Abstract)

Chitko McKown, C.G., Miller, L.C., Lager, K.M., Kehrli Jr, M.E. 2008. Effects of PRRSV infection on TLR-dependent induction of NOS (abstract). Proceedings of the 89th Conference of Research Workers in Animal Health. Poster No. 104P. p. 122.

Characterization of the porcine monocyte-derived cell lines Cdelta2- and Cdelta2+ - (Abstract)

Chitko Mckown, C.G., Chapes, S.K., Miller, L.C., Green, B.T. 2008. Characterization of the porcine monocyte-derived cell lines Cdelta2+ and Cdelta2+ [abstract]. Society for Leukocyte Biology. Poster No. 45.

In depth global analysis of gene expression levels in porcine alveolar macrophages following infection with porcine reproductive and respiratory syndrome virus - (Abstract)

Miller, L., Harhay, G., Lager, K., Kehrli Jr., M., Laegreid, W., Neill, J. 2008. In depth global analysis of gene expression levels in porcine alveolar macrophages following infection with porcine reproductive and respiratory syndrome virus [abstract]. ARK-Genomics Conference 2008: 3rd International Symposium on Animal Functional Genomics. Paper No. ISAFG-P22. p. 38.

Effect of porcine reproductive and respiratory syndrome virus on porcine alveolar macrophage function as determined using serial analysis of gene expression (SAGE) - (Peer Reviewed Journal)

Miller, L.C., Harhay, G.P., Lager, K.M., Smith, T.P., Neill, J.D. 2008. Effect of porcine reproductive and respiratory syndrome virus on porcine alveolar macrophage function as determined using serial analysis of gene expression (SAGE). Developments in Biologicals. 132:169-174.

Development of cell lines from the sheep used to construct the CHORI-243 ovine BAC library - (Peer Reviewed Journal)

Chitko Mckown, C.G., Leonard, J.C., Moscatello, D., Miller, L.C., Freking, B.A. 2008. Development of cell lines from the sheep used to construct the CHORI-243 ovine BAC library. Animal Biotechnology. 19(2):84-88.

Gene Expression Profiling of Porcine Reproductive and Respiratory Syndrome Virus Infected Porcine Alveolar Macrophages - (Abstract)

Miller, L.C., Harhay, G.P., Lager, K.M., Smith, T.P., Neill, J.D. 2007. Gene expression profiling of PRRSV-infected porcine alveolar macrophages [abstract]. Porcine Reproductive and Respiratory Syndrome International Symposium. Paper No. 47.

Determination of the cytokine expression profile after infection of (PK-15) Porcine cells with classical swine fever virus - (Abstract)

Lange, A., Greiser-Wilke, I., Bendfeldt, S., Miller, L.C., Neill, J.D. 2007. Determination of the cytokine expression profile after infection of PK-15 Porcine cells with classical swine fever virus [abstract]. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 137P. p. 118.

Effect of porcine reproductive and respiratory syndrome virus on porcine alveolar macrophage function as determined using serial analysis of gene expression (SAGE) - (Abstract)

Neill, J.D., Miller, L.C., Harhay, G.P., Lager, K.M. 2007. Effect of porcine reproductive and respiratory syndrome virus on porcine alveolar macrophage function as determined using serial analysis of gene expression (SAGE) [abstract]. International Symposium on Animal Genomics for Animal Health. Paper No. PA-070. p. 58.

TYPE I INTERFERON RESPONSES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS INFECTION - (Abstract)

Miller, L.C., Chitko McKown, C.G., Laegreid, W.W. 2005. Type I interferon responses to porcine reproductive and respiratory syndrome virus infection [abstract]. International PRRS Symposium. Poster No. 45.

Structure of Foot-and-mouth Disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation - (Peer Reviewed Journal)

Fry, E.E., Newman, J.W.I., Curry, S., Najjam, S., Jackson, T., Blakemore, W., Lea, S.M., Miller, L., Burman, A., King, A.M.Q., Stuart, D.I. 2005. Structure of Foot-and-mouth Disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation. Journal of General Virology. 86:1909-1920.

DISCRIMINTION OF ESCHERICHIA COLI O157:H7 ISOLATES BY GENOTYPING SINGLE NUCLEOTIDE POLYMORPHISMS - (Abstract)

Bono, J.L., Keen, J.E., Clawson, M.L., Heaton, M.P., Chitko Mckown, C.G., Miller, L.C., Laegreid, W.W. 2005. Discrimintion of Escherichia coli O157:H7 isolates by genotyping single nucleotide polymorphisms. [abstract] American Society of Microbiologists. p. 318.

APOPTOSIS AND PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS - (Abstract)

Miller, L.C., Fox, J.M., Chitko Mckown, C.G., Laegreid, W.W. 2004. Apoptosis and porcine reproductive and respiratory syndrome virus [abstract]. Research Workers in Animal Diseases Conference. p. 101.

DEVELOPMENT AND CHARACTERIZATION OF THREE PORCINE MONOCYTE-DERIVED CELL LINES - (Abstract)

Chitko Mckown, C.G., Green, B.T., Miller, L.C., Mckown, R.D., Laegreid, W.W. 2004. Development and characterization of three porcine monocyte-derived cell lines [abstract]. Research Workers in Animal Diseases Conference. p. 96.

APOPTOSIS AND PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS - (Peer Reviewed Journal)

Miller, L.C., Fox, J.M. 2004. Apoptosis and porcine reproductive and respiratory syndrome virus. Veterinary Immunology and Immunopathology 102(3):131-142.

INTERFERON TYPE I RESPONSE IN PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS-INFECTED MARC-145 CELLS - (Peer Reviewed Journal)

Miller, L.C., Laegreid, W.W., Bono, J.L., Chitko McKown, C.G., Fox, J.M. 2004. Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells. Archives of Virology. 149(12):2453-2463.

EARLY INNATE IMMUNE RESPONSE IN PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS-INFECTED MARC-145 CELLS - (Abstract)

Miller, L.C., Fox, J.M., Bono, J.L., Chitko Mckown, C.G., Laegreid, W.W. 2004. Early innate immune response in porcine reproductive and respiratory syndrome virus-infected marc-145 cells [abstract]. 7th Int. Symp. Positive Strand RNA Viruses. Paper No. P2-G1.

EVALUATION OF A REAL-TIME PCR KIT FOR DETECTING ESCHERICHIA COLI O157 IN BOVINE FECAL SAMPLES - (Peer Reviewed Journal)

BONO, J.L., KEEN, J.E., MILLER, L.C., FOX, J.M., CHITKO MCKOWN, C.G., HEATON, M.P., LAEGREID, W.W. EVALUATION OF A REAL-TIME PCR KIT FOR DETECTING ESCHERICHIA COLI O157 IN BOVINE FECAL SAMPLES. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2004. V. 70. P. 1855-1857.

GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE - (Abstract)

CHITKO MCKOWN, C.G., FOX, J.M., MILLER, L.C., HEATON, M.P., BONO, J.L., KEEN, J.E., GROSSE, W.M., LAEGREID, W.W. GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE. IMMUNOLOGY RESEARCH WORKSHOP. 2003. ABSTRACT NO. 23.

GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE - (Peer Reviewed Journal)

CHITKO MCKOWN, C.G., FOX, J.M., MILLER, L.C., HEATON, M.P., BONO, J.L., KEEN, J.E., GROSSE, W.M., LAEGREID, W.W. GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2004. V. 28. P. 635-645.

IDENTIFICATION OF RESPONSIVE GENES IN PRRSV-INFECTED PULMONARY MACROPHAGES USING SEMI-QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTION PCR (RT-PCR) - (Abstract)

MILLER, L.C., CHITKO MCKOWN, C.G., BONO, J.L., LAEGREID, W.W., FOX, J.M. IDENTIFICATION OF RESPONSIVE GENES IN PRRSV-INFECTED PULMONARY MACROPHAGES USING SEMI-QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTION PCR (RT-PCR). RESEARCH WORKERS IN ANIMAL DISEASES CONFERENCE PROCEEDINGS. 2003. ABSTRACT NO. 155.

ASSOCIATION OF NOS2A HAPLOTYPES AND BACTERICIDAL ACTIVITY OF BOVINE MONOCYTE-DERIVED MACROPHAGES - (Abstract)

CHITKO MCKOWN, C.G., HEATON, M.P., GROSSE, W.M., KEEN, J.E., BONO, J.L., CLAWSON, M.L., FOX, J.M., MILLER, L.C., LAEGREID, W.W. ASSOCIATION OF NOS2A HAPLOTYPES AND BACTERICIDAL ACTIVITY OF BOVINE MONOCYTE-DERIVED MACROPHAGES. AMERICAN ASSOCIATION OF IMMUNOLOGISTS PROCEEDINGS. 2003. Abstract No. 150.1.

DYNAMICS OF GENE EXPRESSION IN PORCINE ARTERIVIRUS INFECTED MARC-145 CELLS - (Abstract)

MILLER, L.C., FOX, J.M. DYNAMICS OF GENE EXPRESSION IN PORCINE ARTERIVIRUS INFECTED MARC-145 CELLS. RESEARCH WORKERS IN ANIMAL DISEASES CONFERENCE PROCEEDINGS. 2002. Abstract No. 101P.